Details for Patent: 8,529,882
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Summary for Patent: 8,529,882
| Title: | Peptidomimetic protease inhibitors |
| Abstract: | The present invention relates to peptidomimetic compounds useful as protease inhibitors, particularly as serine protease inhibitors and more particularly as hepatitis C NS3 protease inhibitors; intermediates thereto; their preparation including novel stereoselective processes to intermediates. The invention is also directed to pharmaceutical compositions and to methods for using the compounds for inhibiting HCV protease or treating a patient suffering from an HCV infection or physiological condition related to the infection. Also provided are pharmaceutical combinations comprising, in addition to one or more HCV serine protease inhibitors, one or more interferons exhibiting anti-HCV activity and/or one or more compounds having anti HCV activity and a pharmaceutically acceptable carrier, and methods for treating or preventing a HCV infection in a patient using the compositions. The present invention is also directed to a kit or pharmaceutical pack for treating or preventing HCV infection in a patient. |
| Inventor(s): | Babine; Robert Edward (Franklin, MA), Chen; Shu Hui (Carmel, IN), Collado; Ivan (Madrid, ES), Garcia-Paredes; Cristina (Madrid, ES), Glass; John Irvin (Indianapolis, IN), Jin; Ling (Carmel, IN), Lamar; Jason Eric (Indianapolis, IN), Parker, III; Raymond Samuel (Doylestown, PA), Snyder; Nancy June (Lizton, IN), Sun; Xicheng David (Superior, CO), Guo; Deqi (Carmel, IN), Yip; Yvonne Yee Mai (Indianapolis, IN), Wang; Q. May (Indianapolis, IN), Victor; Frantz (Indianapolis, IN), Tebbe; Mark Joseph (Hamburg, DE), Perni; Robert B. (Marlborough, MA), Farmer; Luc (Montreal, CA) |
| Assignee: | Vertex Pharmaceuticals Incorporated (Cambridge, MA) |
| Application Number: | 13/541,436 |
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Patent Claim Types: see list of patent claims | Use; Composition; |
Drugs Protected by US Patent 8,529,882
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| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 8,529,882
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| European Patent Office | 1320540 | ⤷ Sign Up | C300518 | Netherlands | ⤷ Sign Up |
| European Patent Office | 1320540 | ⤷ Sign Up | PA2012003,C1320540 | Lithuania | ⤷ Sign Up |
| European Patent Office | 1320540 | ⤷ Sign Up | PA2012003 | Lithuania | ⤷ Sign Up |
| European Patent Office | 1320540 | ⤷ Sign Up | CA 2012 00007 | Denmark | ⤷ Sign Up |
| European Patent Office | 1320540 | ⤷ Sign Up | 91960 | Luxembourg | ⤷ Sign Up |
| European Patent Office | 1320540 | ⤷ Sign Up | 1290007-2 | Sweden | ⤷ Sign Up |
| European Patent Office | 1320540 | ⤷ Sign Up | 12C0018 | France | ⤷ Sign Up |
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
