Details for Patent: 8,642,012
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Which drugs does patent 8,642,012 protect, and when does it expire?
Patent 8,642,012 protects RAVICTI and is included in one NDA.
This patent has forty patent family members in seventeen countries.
Summary for Patent: 8,642,012
| Title: | Methods of treatment using ammonia-scavenging drugs |
| Abstract: | The invention provides a method for determining a dose and schedule and making dose adjustments of PBA prodrugs used to treat nitrogen retention states, or ammonia accumulation disorders, by measuring urinary excretion of phenylacetylglutamine and/or total urinary nitrogen. The invention provides methods to select an appropriate dosage of a PBA prodrug based on the patient's dietary protein intake, or based on previous treatments administered to the patient. The methods are applicable to selecting or modifying a dosing regimen for a subject receiving an orally administered ammonia scavenging drug. |
| Inventor(s): | Scharschmidt; Bruce (South San Francisco, CA) |
| Assignee: | Hyperion Therapeutics, Inc. (South San Francisco, CA) |
| Application Number: | 12/350,111 |
| Patent Litigation and PTAB cases: | See patent lawsuits and PTAB cases for patent 8,642,012 |
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Patent Claim Types: see list of patent claims | Use; |
Drugs Protected by US Patent 8,642,012
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Horizon Therap Us | RAVICTI | glycerol phenylbutyrate | LIQUID;ORAL | 203284-001 | Feb 1, 2013 | RX | Yes | Yes | ⤷ Sign Up | ⤷ Sign Up | DOSAGE ADJUSTMENT OF A NITROGEN SCAVENGING DRUG IN THE TREATMENT OF A UREA CYCLE DISORDER | ⤷ Sign Up | ||||
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 8,642,012
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| European Patent Office | 2330892 | ⤷ Sign Up | PA2016041 | Lithuania | ⤷ Sign Up |
| European Patent Office | 2330892 | ⤷ Sign Up | CA 2016 00062 | Denmark | ⤷ Sign Up |
| European Patent Office | 2330892 | ⤷ Sign Up | 300854 | Netherlands | ⤷ Sign Up |
| European Patent Office | 2330892 | ⤷ Sign Up | 122016000107 | Germany | ⤷ Sign Up |
| European Patent Office | 2330892 | ⤷ Sign Up | C20160044 00204 | Estonia | ⤷ Sign Up |
| European Patent Office | 2330892 | ⤷ Sign Up | CR 2016 00062 | Denmark | ⤷ Sign Up |
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
