Details for Patent: 8,664,231

Which drugs does patent 8,664,231 protect, and when does it expire?

Patent 8,664,231 protects RASUVO and is included in one NDA.

This patent has twenty-nine patent family members in twenty-one countries.

Summary for Patent: 8,664,231

Title:	Concentrated methotrexate solutions
Abstract:	Concentrated methotrexate solutions are described which are suitable for the use of an active substance in the production of a parenterally administered medicament for the treatment of inflammatory autoimmune diseases. The methotrexate is added to a pharmaceutically acceptable solvent at a concentration of more than 30 mg/ml. The invention also relates to a ready-made syringe and a carpule containing such a pharmaceutical solution formulation, as well as a pen injector comprising such a carpule and/or a ready-made syringe.
Inventor(s):	Will; Heiner (Hamburg, DE)
Assignee:	Medac Gesellschaft fuer Klinische Spezialpraepararate mbH (Wedel, DE)
Application Number:	12/374,528
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 8,664,231
Patent Claim Types: see list of patent claims	Use; Formulation; Device; Dosage form;

Drugs Protected by US Patent 8,664,231

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
Medexus	RASUVO	methotrexate	SOLUTION;SUBCUTANEOUS	205776-001	Jul 10, 2014		RX	Yes	Yes						SUBCUTANEOUS INJECTION OF METHOTREXATE
Medexus	RASUVO	methotrexate	SOLUTION;SUBCUTANEOUS	205776-002	Jul 10, 2014		RX	Yes	Yes						SUBCUTANEOUS INJECTION OF METHOTREXATE
Medexus	RASUVO	methotrexate	SOLUTION;SUBCUTANEOUS	205776-003	Jul 10, 2014		RX	Yes	Yes						SUBCUTANEOUS INJECTION OF METHOTREXATE
Medexus	RASUVO	methotrexate	SOLUTION;SUBCUTANEOUS	205776-004	Jul 10, 2014		RX	Yes	Yes						SUBCUTANEOUS INJECTION OF METHOTREXATE
Medexus	RASUVO	methotrexate	SOLUTION;SUBCUTANEOUS	205776-005	Jul 10, 2014		RX	Yes	Yes						SUBCUTANEOUS INJECTION OF METHOTREXATE
Medexus	RASUVO	methotrexate	SOLUTION;SUBCUTANEOUS	205776-006	Jul 10, 2014		RX	Yes	Yes						SUBCUTANEOUS INJECTION OF METHOTREXATE

Foreign Priority and PCT Information for Patent: 8,664,231

Foriegn Application Priority Data
Foreign Country	Foreign Patent Number	Foreign Patent Date
Germany	10 2006 033 837	Jul 21, 2006

PCT Information
PCT Filed	July 20, 2007	PCT Application Number:	PCT/EP2007/006491
PCT Publication Date:	January 24, 2008	PCT Publication Number:	WO2008/009476

International Family Members for US Patent 8,664,231

Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Austria	14872
Austria	E491455
Australia	2007276387
Brazil	PI0715433
Canada	2659662
Canada	2869671