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Last Updated: January 6, 2025

Details for Patent: 8,835,430


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Summary for Patent: 8,835,430
Title:2,4-pyrimidinediamine compounds and their uses
Abstract: The present invention provides 2,4-pyrimidinediamine compounds that inhibit the IgE and/or IgG receptor signaling cascades that lead to the release of chemical mediators, intermediates and methods of synthesizing the compounds and methods of using the compounds in a variety of contexts, including in the treatment and prevention of diseases characterized by, caused by or associated with the release of chemical mediators via degranulation and other processes effected by activation of the IgE and/or IgG receptor signaling cascades.
Inventor(s): Singh; Rajinder (Belmont, CA), Argade; Ankush (Foster City, CA), Payan; Donald (Hillsborough, CA), Molineaux; Susan (San Francisco, CA), Holland; Sacha (San Francisco, CA), Clough; Jeffrey (Redwood City, CA), Keim; Holger (Irvine, CA), Bhamidipati; Somasekhar (Foster City, CA), Sylvain; Catherine (San Mateo, CA), Li; Hui (Santa Clara, CA), Rossi; Alexander (Reedsport, OR)
Assignee: Rigel Pharmaceuticals, Inc. (South San Francisco, CA)
Application Number:14/038,521
Patent Claim Types:
see list of patent claims
Composition; Compound;
Patent landscape, scope, and claims:

Detailed Analysis of the Scope and Claims of United States Patent 8,835,430

Introduction

United States Patent 8,835,430, titled "2,4-pyrimidinediamine compounds and their uses," is a patent that focuses on specific chemical compounds and their applications. This analysis will delve into the scope, claims, and the broader patent landscape surrounding this invention.

Patent Overview

Patent Number and Title

  • The patent number is US8835430B2, and the title is "2,4-pyrimidinediamine compounds and their uses."

Publication and Prior Art

  • The patent was published on September 16, 2014, with a prior art date of March 15, 2013[4].

Scope of the Patent

Invention Description

  • The patent describes 2,4-pyrimidinediamine compounds that inhibit the IgE and/or IgG receptor signaling cascades. These compounds are designed to prevent the release of mediators involved in allergic reactions, making them potentially useful in treating allergic diseases[4].

Chemical Structure

  • The compounds are characterized by their specific chemical structure, which includes a pyrimidine ring with diamine substituents. Variations in the structure, such as the presence of fluoro or chloro groups, are also discussed[4].

Claims of the Patent

Independent and Dependent Claims

  • The patent includes both independent and dependent claims. Independent claims define the broad scope of the invention, while dependent claims narrow down the scope by adding specific limitations.
    • For example, Claim 1 might describe the general structure of the 2,4-pyrimidinediamine compounds, while dependent claims (e.g., Claims 2-10) might specify particular substituents or uses of these compounds[4].

Use Claims

  • The patent also includes use claims, which outline the therapeutic applications of the compounds. These claims are crucial as they define how the compounds can be used to treat specific medical conditions, such as allergic diseases[4].

Patent Landscape Analysis

Technology Area

  • This patent falls under the broader technology area of pharmaceuticals and biotechnology, specifically within the field of immunology and allergy treatment.
    • According to the USPTO classification, such patents would be categorized under the World Intellectual Property Organization (WIPO) classification system, likely within the fields of organic chemistry or pharmaceuticals[1].

Competitor Analysis

  • A patent landscape analysis would reveal other key players in this technology area. For instance, companies like Pfizer, Merck, or biotech firms specializing in immunology might have significant patent portfolios related to similar compounds or therapeutic applications.
    • A comprehensive analysis would show the saturation level in this technology area, helping to identify whether there is room for innovation or if the space is highly competitive[3].

Saturation and Innovation

  • The patent landscape analysis can also help in identifying areas of high patent saturation and areas where there is still room for innovation.
    • For example, if the analysis shows a high number of patents related to IgE and IgG receptor signaling cascades, it might indicate a need to pivot towards newer inventive spaces to avoid infringement and to find unexplored areas of innovation[3].

Strategic Insights

R&D and Business Decisions

  • A full patent landscape analysis can provide strategic insights for R&D and business management. It helps in making long-term decisions about whether to invest in this technology area or to explore other avenues.
    • For instance, if the analysis reveals that the current technology area is highly saturated, it might be advisable to focus resources on newer, less crowded areas of research[3].

Legal and Regulatory Considerations

Infringement and Licensing

  • Understanding the patent landscape is crucial for avoiding infringement claims. Companies must ensure that their new compounds or uses do not infringe on existing patents.
    • Legal considerations, such as those outlined in the DFARS (Defense Federal Acquisition Regulation Supplement), are important for processing licenses, assignments, and infringement claims, especially in the context of government contracts[5].

Public and Stakeholder Engagement

Feedback and Comments

  • While the specific patent in question may not have undergone a public comment period, the process of engaging stakeholders is crucial in patent law.
    • For example, the Administrative Conference of the United States (ACUS) has engaged in studies and public comment periods to gather input on patent-related issues, such as the feasibility of a small claims patent court[2].

Key Takeaways

  • Specific Chemical Compounds: The patent focuses on 2,4-pyrimidinediamine compounds with specific therapeutic applications.
  • Therapeutic Uses: The compounds are designed to inhibit IgE and IgG receptor signaling cascades, making them useful in treating allergic diseases.
  • Patent Landscape: The technology area is part of the broader pharmaceutical and biotechnology sector, with potential high saturation levels.
  • Strategic Insights: A comprehensive patent landscape analysis is essential for making informed R&D and business decisions.
  • Legal Considerations: Understanding patent infringement and licensing is critical to avoid legal issues.

FAQs

1. What is the main focus of United States Patent 8,835,430?

  • The main focus is on 2,4-pyrimidinediamine compounds and their therapeutic uses, particularly in inhibiting IgE and IgG receptor signaling cascades.

2. How does this patent fit into the broader technology area?

  • It falls under the pharmaceuticals and biotechnology sector, specifically within immunology and allergy treatment.

3. What is the importance of patent landscape analysis in this context?

  • It helps in identifying areas of high patent saturation, making informed R&D and business decisions, and avoiding infringement claims.

4. What are some potential legal considerations for this patent?

  • Ensuring that new compounds or uses do not infringe on existing patents and understanding licensing and assignment procedures are crucial.

5. How can stakeholders engage with patent-related issues?

  • Through public comment periods and consultative groups, as seen in studies conducted by ACUS.

Sources

  1. Invention: U.S. and Comparative Global Trends - NCSES, January 15, 2020.
  2. U.S. Patent Small Claims Court - ACUS.
  3. Patent Landscape Analysis - Uncovering Strategic Insights - AcclaimIP.
  4. US8835430B2 - 2,4-pyrimidinediamine compounds and their uses - Google Patents.
  5. SUBPART 227.70 INFRINGEMENT CLAIMS, LICENSES, AND ... - Acq.osd.mil.

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Drugs Protected by US Patent 8,835,430

ApplicantTradenameGeneric NameDosageNDAApproval DateTETypeRLDRSPatent No.Patent ExpirationProductSubstanceDelist Req.Patented / Exclusive UseSubmissiondate
No data available in table
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>TE>Type>RLD>RS>Patent No.>Patent Expiration>Product>Substance>Delist Req.>Patented / Exclusive Use>Submissiondate
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International Family Members for US Patent 8,835,430

CountryPatent NumberEstimated ExpirationSupplementary Protection CertificateSPC CountrySPC Expiration
Australia 2003208931 ⤷  Subscribe
Australia 2003265336 ⤷  Subscribe
Australia 2008252053 ⤷  Subscribe
Austria 451104 ⤷  Subscribe
Austria 524184 ⤷  Subscribe
Brazil 0307355 ⤷  Subscribe
>Country>Patent Number>Estimated Expiration>Supplementary Protection Certificate>SPC Country>SPC Expiration
Showing 1 to 6 of 6 entries

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