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Last Updated: March 14, 2025

Details for Patent: 8,927,710


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Which drugs does patent 8,927,710 protect, and when does it expire?

Patent 8,927,710 protects XOFLUZA and is included in two NDAs.

This patent has thirty-eight patent family members in seventeen countries.

Summary for Patent: 8,927,710
Title:Substituted polycyclic carbamoylpyridone derivative
Abstract: This invention provides compounds having antiviral activities especially inhibiting activity for influenza virus, more preferably provides substituted 3-hydroxy-4-pyridone derivatives having cap-dependent endonuclease inhibitory activity.
Inventor(s): Akiyama; Toshiyuki (Osaka, JP), Takaya; Kenji (Osaka, JP), Kawai; Makoto (Osaka, JP), Taoda; Yoshiyuki (Osaka, JP), Mikamiyama; Minako (Osaka, JP), Morimoto; Kenji (Osaka, JP), Kageyama; Chika (Osaka, JP), Tomita; Kenji (Osaka, JP), Mikamiyama; Hidenori (Osaka, JP), Suzuki; Naoyuki (Osaka, JP)
Assignee: Shionogi & Co., Ltd. (Osaka, JP)
Application Number:13/378,334
Patent Claim Types:
see list of patent claims
Use; Composition; Compound;
Patent landscape, scope, and claims:

United States Patent 8,927,710: A Detailed Analysis of Scope, Claims, and Patent Landscape

Introduction

United States Patent 8,927,710, issued to the Scripps Research Institute, protects novel compounds and compositions with significant antiviral activities, particularly against the influenza virus. This patent is a crucial piece in the broader landscape of pharmaceutical and biomedical innovation. Here, we delve into the scope, claims, and the surrounding patent landscape to understand its implications and significance.

Patent Overview

Invention Description

The patent describes substituted polycyclic carbamoylpyridone derivatives, which are compounds designed to inhibit the influenza virus. These compounds are part of a broader class of antiviral agents and are characterized by their specific chemical structures and substituents[4].

Publication and Legal Status

The patent was published on December 30, 2014, and is currently active, with an expiration date determined by the patent term. The legal status indicates that it is still in force, although this is subject to change based on various factors such as maintenance payments and potential legal challenges[4].

Scope of the Patent

Patent Scope Metrics

The scope of a patent is often measured by metrics such as independent claim length and independent claim count. These metrics help in understanding the breadth and clarity of the patent claims. For Patent 8,927,710, the scope would be evaluated based on these claims to determine their breadth and how they have evolved during the examination process[3].

Claim Language and Clarity

The patent claims are detailed and specific, outlining the chemical structures and the conditions under which these compounds exhibit antiviral activity. The clarity of these claims is crucial as it affects the patent's validity and the potential for litigation. Narrower claims, as seen in this patent, are generally associated with a higher probability of grant and a shorter examination process[3].

Claims Analysis

Independent Claims

The independent claims in Patent 8,927,710 define the core inventions and are critical in determining the patent's scope. These claims specify the chemical compounds, their structures, and the methods of their use. For example, Claim 1 might describe a specific substituted polycyclic carbamoylpyridone derivative, while subsequent claims might detail variations or methods of use[4].

Dependent Claims

Dependent claims build upon the independent claims and provide additional details or variations. These claims help in broadening the protection while ensuring that the core invention remains clearly defined. In this patent, dependent claims would likely cover different substituents, dosages, or methods of administration.

Patent Landscape

Global Patent Family

To understand the full extent of the patent protection, it is essential to look at the global patent family. This involves using tools like the Global Dossier, which provides access to file histories of related applications from participating IP Offices. For Patent 8,927,710, this would include any corresponding patents or applications filed in other countries, such as Europe, Japan, or China[1].

Prior Art and Citations

The Common Citation Document (CCD) is a valuable resource for understanding the prior art cited by various patent offices. This tool consolidates citation data, enabling a comprehensive view of the prior art landscape for the same invention across different offices. For this patent, analyzing the CCD would reveal how the invention stands in relation to existing knowledge in the field[1].

Competitor Patents

The pharmaceutical industry is highly competitive, and understanding the patent landscape involves identifying similar patents held by competitors. This can be done through databases like those provided by the European Patent Office (EPO), Japan Patent Office (JPO), and the World Intellectual Property Organization (WIPO)[1].

International Patent Search

European Patent Office (EPO)

Using the EPO's esp@cenet database, one can search for European patents related to antiviral compounds. This database also provides machine translations for some languages, which can be helpful in understanding the scope of European patents[1].

Japan Patent Office (JPO) and Other Offices

Similar searches can be conducted through the JPO and other international patent offices. These searches help in identifying whether similar compounds or methods have been patented elsewhere, which is crucial for global market strategy and potential collaborations or licensing agreements[1].

Impact on Innovation

Incentives for Innovation

The clarity and breadth of patent claims, as seen in Patent 8,927,710, play a significant role in incentivizing innovation. Narrower, clearer claims reduce the risk of litigation and licensing costs, thereby encouraging further research and development in the field[3].

Licensing and Collaboration

The patent's scope and claims also influence licensing and collaboration opportunities. Clear and specific claims make it easier for other companies to understand what is protected and what is available for licensing or collaboration, fostering a more dynamic innovation ecosystem.

Conclusion

United States Patent 8,927,710 is a significant contribution to the field of antiviral research, particularly in the context of influenza treatment. Understanding its scope, claims, and the broader patent landscape is essential for both the patent holders and other stakeholders in the pharmaceutical industry.

Key Takeaways

  • Patent Scope: Measured by independent claim length and count, which affect the patent's breadth and clarity.
  • Claims Analysis: Independent and dependent claims define the core invention and its variations.
  • Global Patent Family: Understanding the global patent family through tools like the Global Dossier.
  • Prior Art and Citations: Analyzing the Common Citation Document to understand the prior art landscape.
  • International Patent Search: Searching databases from various international patent offices to identify similar patents.
  • Impact on Innovation: Clear and narrower claims incentivize innovation and facilitate licensing and collaboration.

FAQs

Q: What is the main invention protected by United States Patent 8,927,710?

A: The patent protects substituted polycyclic carbamoylpyridone derivatives with antiviral activities, particularly against the influenza virus.

Q: How is the scope of a patent measured?

A: The scope of a patent is often measured by metrics such as independent claim length and independent claim count.

Q: What is the significance of the Global Dossier in patent searching?

A: The Global Dossier provides access to file histories of related applications from participating IP Offices, helping users understand the global patent family.

Q: Why are clear and narrower patent claims important?

A: Clear and narrower claims reduce the risk of litigation and licensing costs, thereby encouraging further research and development.

Q: How can one search for similar patents internationally?

A: One can use databases from international patent offices such as the EPO, JPO, and WIPO to search for similar patents.

Sources

  1. USPTO: Search for patents - USPTO
  2. DrugPatentWatch: Drugs covered by patent 8,927,710. Claims, international patent ...
  3. SSRN: Patent Claims and Patent Scope - Search eLibrary :: SSRN
  4. Google Patents: US8927710B2 - Substituted polycyclic carbamoylpyridone derivative
  5. PubChem: Substituted polycyclic carbamoylpyridone derivative - Patent PL ...

More… ↓

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Drugs Protected by US Patent 8,927,710

ApplicantTradenameGeneric NameDosageNDAApproval DateTETypeRLDRSPatent No.Patent ExpirationProductSubstanceDelist Req.Patented / Exclusive UseSubmissiondate
Genentech Inc XOFLUZA baloxavir marboxil FOR SUSPENSION;ORAL 214410-001 Nov 23, 2020 RX Yes Yes ⤷  Try for Free ⤷  Try for Free Y ⤷  Try for Free
Genentech Inc XOFLUZA baloxavir marboxil TABLET;ORAL 210854-001 Oct 24, 2018 DISCN Yes No ⤷  Try for Free ⤷  Try for Free Y ⤷  Try for Free
Genentech Inc XOFLUZA baloxavir marboxil TABLET;ORAL 210854-002 Oct 24, 2018 RX Yes No ⤷  Try for Free ⤷  Try for Free Y ⤷  Try for Free
Genentech Inc XOFLUZA baloxavir marboxil TABLET;ORAL 210854-003 Mar 18, 2021 RX Yes Yes ⤷  Try for Free ⤷  Try for Free Y ⤷  Try for Free
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>TE>Type>RLD>RS>Patent No.>Patent Expiration>Product>Substance>Delist Req.>Patented / Exclusive Use>Submissiondate
Showing 1 to 4 of 4 entries

Foreign Priority and PCT Information for Patent: 8,927,710

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan2009-142166Jun 15, 2009
PCT Information
PCT FiledJune 14, 2010PCT Application Number:PCT/JP2010/060006
PCT Publication Date:December 23, 2010PCT Publication Number: WO2010/147068

International Family Members for US Patent 8,927,710

CountryPatent NumberEstimated ExpirationSupplementary Protection CertificateSPC CountrySPC Expiration
China 102482219 ⤷  Try for Free
China 102803260 ⤷  Try for Free
China 104151234 ⤷  Try for Free
China 104230795 ⤷  Try for Free
China 105037259 ⤷  Try for Free
Denmark 2444400 ⤷  Try for Free
>Country>Patent Number>Estimated Expiration>Supplementary Protection Certificate>SPC Country>SPC Expiration
Showing 1 to 6 of 6 entries

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Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.