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Last Updated: December 27, 2024

Details for Patent: 9,000,018


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Which drugs does patent 9,000,018 protect, and when does it expire?

Patent 9,000,018 protects PONVORY and is included in one NDA.

This patent has thirty-four patent family members in twenty-five countries.

Summary for Patent: 9,000,018
Title:Thiazolidin-4-one-derivatives
Abstract: The invention relates to pharmaceutical compositions containing at least one thiazolidin-4-one derivative to prevent or treat disorders associated with an activated immune system. Furthermore, the invention relates to novel thiazolidin-4-one derivatives notably for use as pharmaceutically active compounds. Said compounds particularly act also as immunosuppressive agents.
Inventor(s): Binkert; Christoph (Basel, CH), Bolli; Martin (Allschwil, CH), Mathys; Boris (Egerkingen, CH), Mueller; Claus (Weil am Rhein, CH), Scherz; Michael (Ettingen, CH), Nayler; Oliver (Arlesheim, CH)
Assignee: Actelion Pharmaceuticals, Ltd (Allschwil, CH)
Application Number:13/951,954
Patent Claim Types:
see list of patent claims
Use; Composition;
Patent landscape, scope, and claims:

Analyzing the Scope and Claims of United States Patent 9,000,018: A Comprehensive Review

Introduction

United States Patent 9,000,018, titled "Thiazolidin-4-one-derivatives," is a patent that has significant implications in the pharmaceutical industry, particularly in the treatment and prevention of various disorders. This article delves into the details of the patent's scope, claims, and the broader patent landscape to provide a thorough understanding of its importance and impact.

Patent Overview

Publication and Legal Status

The patent, US 9,000,018 B2, was published on April 7, 2015, and has since expired due to the completion of its lifetime[1][5].

Inventive Subject Matter

The patent pertains to pharmaceutical compositions containing at least one thiazolidin-4-one derivative. These derivatives are designed to prevent or treat disorders associated with various biological pathways. The invention highlights the therapeutic potential of these compounds, which could be crucial in addressing unmet medical needs.

Scope of the Patent

Claim Structure

The patent includes multiple claims that define the scope of the invention. These claims are categorized into independent and dependent claims. Independent claims broadly define the invention, while dependent claims narrow down the scope by adding specific limitations to the independent claims. For instance, the patent might include claims that describe the chemical structure of the thiazolidin-4-one derivatives, the methods of synthesis, and the therapeutic applications[1][5].

Metrics for Measuring Patent Scope

Research on patent scope often uses metrics such as independent claim length and independent claim count to assess the breadth and clarity of the patent. A study on patent scope metrics indicates that narrower claims at publication are associated with a higher probability of grant and a shorter examination process, which could be relevant in understanding the strategy behind the claims in US 9,000,018[3].

Claims Analysis

Independent Claims

Independent claims in the patent define the core aspects of the invention. For example, these claims might describe the specific chemical structures of the thiazolidin-4-one derivatives, their pharmacological activities, and the disorders they are intended to treat. These claims are critical as they set the boundaries of what is considered novel and non-obvious under patent law[1].

Dependent Claims

Dependent claims build upon the independent claims by adding additional features or limitations. These claims help to further define the invention and can include specifics about the synthesis methods, dosage forms, and specific therapeutic applications. Dependent claims can provide additional protection by covering various aspects of the invention that are not explicitly mentioned in the independent claims[1].

Therapeutic Applications

Disorders Treated

The thiazolidin-4-one derivatives covered by the patent are intended to treat a range of disorders. These could include metabolic disorders, inflammatory diseases, or other conditions where the biological pathways targeted by these compounds are implicated. The specific disorders and the mechanisms by which these compounds act are detailed in the patent's claims and description[1][5].

Mechanism of Action

Understanding the mechanism of action of these derivatives is crucial for their therapeutic application. The patent likely includes detailed descriptions of how these compounds interact with biological targets, their pharmacokinetics, and their potential side effects. This information is vital for clinicians and researchers looking to develop new treatments based on these compounds.

Patent Landscape

Related Patents and Prior Art

The patent landscape surrounding US 9,000,018 includes other patents related to thiazolidin-4-one derivatives and similar therapeutic compounds. Prior art keywords such as "thiazolidin," "ylidene," "benz," "hydroxy," and "ethoxy" indicate the relevance of these terms in the broader context of pharmaceutical research[1].

Competitive Environment

The pharmaceutical industry is highly competitive, with numerous companies and research institutions vying for patent protection for their discoveries. The existence of US 9,000,018 and similar patents highlights the ongoing research and development in this area. Companies and researchers must navigate this complex landscape to ensure their innovations are novel and non-obvious over existing patents.

Impact on Innovation

Licensing and Litigation

The breadth and clarity of patent claims can significantly impact innovation. Broader claims can lead to increased licensing and litigation costs, potentially discouraging innovation. However, well-defined and narrower claims, as seen in US 9,000,018, can provide clear boundaries and encourage further research and development in the field[3].

Public Health Implications

The therapeutic applications of thiazolidin-4-one derivatives have significant public health implications. By providing new treatment options for various disorders, these compounds can improve patient outcomes and quality of life. The patent's expiration allows for the potential generic production of these compounds, making them more accessible to a wider population.

Stakeholder Perspectives

Researchers and Clinicians

For researchers and clinicians, the patent provides valuable information on the synthesis, pharmacology, and therapeutic applications of thiazolidin-4-one derivatives. This information can be used to develop new treatments and conduct further research into the mechanisms of action of these compounds.

Pharmaceutical Companies

Pharmaceutical companies must consider the patent landscape when developing new drugs. The existence of US 9,000,018 and similar patents requires companies to ensure their products do not infringe on existing patents, or to negotiate licensing agreements to use the patented technology.

Public Policy and Legal Considerations

Small Claims Patent Court

The concept of a small claims patent court, as studied by the Administrative Conference of the United States (ACUS), could have implications for the enforcement and litigation of patents like US 9,000,018. Such a court could provide a more streamlined and cost-effective way to resolve patent disputes, which could be particularly beneficial for small entities and individual inventors[2].

Key Takeaways

  • Patent Scope and Claims: The patent includes detailed claims that define the scope of the invention, including the chemical structures, synthesis methods, and therapeutic applications of thiazolidin-4-one derivatives.
  • Therapeutic Applications: The compounds are intended to treat various disorders, with detailed descriptions of their mechanisms of action and potential side effects.
  • Patent Landscape: The patent is part of a broader landscape of related patents and prior art, highlighting the competitive and innovative environment in pharmaceutical research.
  • Impact on Innovation: Well-defined claims can encourage innovation by providing clear boundaries, while the patent's expiration can make the compounds more accessible for generic production.
  • Stakeholder Perspectives: The patent is crucial for researchers, clinicians, and pharmaceutical companies, providing valuable information and guiding further research and development.

FAQs

What is the main subject matter of US Patent 9,000,018?

The main subject matter of US Patent 9,000,018 is pharmaceutical compositions containing at least one thiazolidin-4-one derivative, intended to prevent or treat various disorders.

What are the key metrics for measuring patent scope?

Key metrics for measuring patent scope include independent claim length and independent claim count, which can indicate the breadth and clarity of the patent.

How does the patent's expiration affect its accessibility?

The expiration of the patent allows for the potential generic production of the thiazolidin-4-one derivatives, making them more accessible to a wider population.

What is the significance of the patent landscape for US 9,000,018?

The patent landscape includes related patents and prior art, highlighting the competitive environment in pharmaceutical research and the need for clear and well-defined claims to avoid infringement.

How could a small claims patent court impact the enforcement of patents like US 9,000,018?

A small claims patent court could provide a more streamlined and cost-effective way to resolve patent disputes, which could be particularly beneficial for small entities and individual inventors.

Sources

  1. US9000018B2 - Thiazolidin-4-one-derivatives - Google Patents
  2. U.S. Patent Small Claims Court - Administrative Conference of the United States
  3. Patent Claims and Patent Scope - SSRN
  4. What Is the Probability of Receiving a US Patent? - Yale Journal of Law and Technology
  5. US-9000018-B2 - Thiazolidin-4-one-derivatives - Unified Patents

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Drugs Protected by US Patent 9,000,018

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Vanda Pharms Inc PONVORY ponesimod TABLET;ORAL 213498-001 Mar 18, 2021 RX Yes Yes ⤷  Subscribe ⤷  Subscribe REDUCTION OF CIRCULATING LYMPHOCYTES IN TREATING RELAPSING FORMS OF MULTIPLE SCLEROSIS (MS), TO INCLUDE CLINICALLY ISOLATED SYNDROME, RELAPSING-REMITTING DISEASE, AND ACTIVE SECONDARY PROGRESSIVE DISEASE, IN ADULTS ⤷  Subscribe
Vanda Pharms Inc PONVORY ponesimod TABLET;ORAL 213498-002 Mar 18, 2021 RX Yes No ⤷  Subscribe ⤷  Subscribe REDUCTION OF CIRCULATING LYMPHOCYTES IN TREATING RELAPSING FORMS OF MULTIPLE SCLEROSIS (MS), TO INCLUDE CLINICALLY ISOLATED SYNDROME, RELAPSING-REMITTING DISEASE, AND ACTIVE SECONDARY PROGRESSIVE DISEASE, IN ADULTS ⤷  Subscribe
Vanda Pharms Inc PONVORY ponesimod TABLET;ORAL 213498-003 Mar 18, 2021 RX Yes No ⤷  Subscribe ⤷  Subscribe REDUCTION OF CIRCULATING LYMPHOCYTES IN TREATING RELAPSING FORMS OF MULTIPLE SCLEROSIS (MS), TO INCLUDE CLINICALLY ISOLATED SYNDROME, RELAPSING-REMITTING DISEASE, AND ACTIVE SECONDARY PROGRESSIVE DISEASE, IN ADULTS ⤷  Subscribe
Vanda Pharms Inc PONVORY ponesimod TABLET;ORAL 213498-004 Mar 18, 2021 RX Yes No ⤷  Subscribe ⤷  Subscribe REDUCTION OF CIRCULATING LYMPHOCYTES IN TREATING RELAPSING FORMS OF MULTIPLE SCLEROSIS (MS), TO INCLUDE CLINICALLY ISOLATED SYNDROME, RELAPSING-REMITTING DISEASE, AND ACTIVE SECONDARY PROGRESSIVE DISEASE, IN ADULTS ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 9,000,018

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
PCT/EP2003/013072Nov 21, 2003

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