Details for Patent: 9,248,195

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Summary for Patent: 9,248,195

Title:	Abuse-deterrent pharmaceutical compositions of opioids and other drugs
Abstract:	An abuse-deterrent pharmaceutical composition has been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opioids. In a preferred embodiment, a drug is modified to increase its lipophilicity. In some embodiments the modified drug is homogeneously dispersed within spherical microparticles composed of a material that is either slowly soluble or not soluble in water. In some embodiments the drug containing microparticles or drug particles are coated with one or more coating layers, where at least one coating is water insoluble and/or organic solvent insoluble. The abuse-deterrent composition retards the release of drug, even if the physical integrity of the formulation is compromised (for example, by chopping with a blade or crushing) and the resulting material is placed in water, snorted, or swallowed. However, when administered as directed, the drug is slowly released from the composition as the composition is passes through the GI tract.
Inventor(s):	Rariy; Roman V. (Allston, MA), Fleming; Alison B. (North Attleboro, MA), Hirsh; Jane (Wellesley, MA), Klibanov; Alexander M. (Boston, MA)
Assignee:	Collegium Pharmaceutical, Inc. (Canton, MA)
Application Number:	14/054,513
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 9,248,195
Patent Claim Types: see list of patent claims	Use; Composition; Dosage form; Formulation;

Drugs Protected by US Patent 9,248,195

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

International Family Members for US Patent 9,248,195

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Cyprus	1119831	⤷ Sign Up
Denmark	1765292	⤷ Sign Up
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