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Last Updated: December 24, 2024

Details for Patent: 9,365,500


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Summary for Patent: 9,365,500
Title:9-aminomethyl substituted minocycline compounds
Abstract: The present invention pertains, at least in part, to novel 9-substituted minocycline compounds. These minocycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and minocycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
Inventor(s): Nelson; Mark L. (Norfolk, MA), Frechette; Roger (Reading, MA), Ismail; Mohamed Y. (Bedford, MA), Honeyman; Laura (Etobicoke, CA), Bowser; Todd (Charlton, MA), Bhatia; Beena (Mansfield, MA)
Assignee: PARATEK PHARMACEUTICALS, INC. (Boston, MA)
Application Number:14/318,031
Patent Claim Types:
see list of patent claims
Use; Composition;
Patent landscape, scope, and claims:

United States Patent 9,365,500: A Detailed Analysis

Overview of the Patent

United States Patent 9,365,500, titled "9-aminomethyl substituted minocycline compounds," is a patent that pertains to a specific class of minocycline derivatives and their methods of use. Here, we will delve into the scope, claims, and the broader patent landscape surrounding this invention.

Background and Invention

Minocycline is a semi-synthetic derivative of tetracycline, widely used as an antibiotic. The patent in question focuses on 9-aminomethyl substituted minocycline compounds, which are designed to enhance the therapeutic efficacy and reduce the side effects associated with traditional minocycline.

Scope of the Patent

The scope of this patent encompasses the chemical compounds themselves, as well as methods for their use in treating various conditions responsive to tetracycline compounds. Here are some key aspects:

Chemical Compounds

The patent describes the synthesis and structure of 9-aminomethyl substituted minocycline compounds. These compounds include various alkyl, cyano, nitro, and sulfonamido groups attached to the minocycline backbone[1].

Therapeutic Uses

The compounds are intended for treating bacterial infections and other conditions that are responsive to tetracycline antibiotics. The patent highlights the potential of these derivatives to offer improved pharmacokinetic profiles and reduced side effects compared to existing minocycline formulations.

Claims of the Patent

The claims of the patent are crucial as they define the legal boundaries of the invention. Here are the main types of claims:

Composition of Matter Claims

These claims cover the specific chemical structures of the 9-aminomethyl substituted minocycline compounds. They detail the molecular composition and the various substituents that can be attached to the minocycline core[1].

Method of Use Claims

These claims pertain to the methods of using the compounds to treat subjects suffering from tetracycline-responsive states. This includes the administration routes, dosages, and treatment regimens.

Process Claims

These claims may include the methods of synthesizing the compounds, which are essential for manufacturing and reproducing the invention.

Patent Landscape Analysis

To understand the broader context of this patent, a patent landscape analysis is essential.

Competitors and Market Trends

Patent landscape analysis reveals that the antibiotic market is highly competitive, with numerous patents filed for various tetracycline derivatives. Companies and research institutions are continually seeking to improve existing antibiotics to combat antibiotic resistance and reduce side effects[3].

Legal Status and Expiry Dates

The patent US9365500B2 has expired due to fee-related issues. However, understanding the legal status and expected expiry dates of similar patents is crucial for strategic planning. This information helps in identifying when patents will lapse, allowing for potential generic or follow-on innovations[3].

Global Patent Family

The patent family for this invention includes related applications filed in various countries. Using tools like the Global Dossier, one can track the status of these applications and identify any office actions or citations that may impact the patent's validity or scope[4].

Determining Inventorship

Inventorship is a critical aspect of patent law, and errors in identifying the true and only inventors can have significant legal implications.

Conception and Reduction to Practice

The conception of the idea for these 9-aminomethyl substituted minocycline compounds and the reduction of this idea to practice are key steps in determining inventorship. Only those who conceived the definite and permanent idea of the invention should be listed as inventors[2].

Correcting Inventorship Errors

Errors in inventorship can be corrected, but deceptive intent in naming inventors can render the patent unenforceable. Ensuring accurate inventorship is vital to maintain the patent's validity and enforceability[2].

Strategic Implications

Understanding the scope and claims of this patent, along with the broader patent landscape, is crucial for strategic decision-making.

Licensing and Collaboration

Companies may consider licensing agreements or collaborations to leverage the technology described in this patent. Patent landscape analysis helps in identifying potential partners and competitors[3].

Litigation and Enforcement

Knowing the legal status and claims of this patent can aid in litigation strategies. For instance, if a similar patent is about to expire, it may open up opportunities for generic or follow-on products[3].

Key Takeaways

  • Chemical Compounds: The patent covers 9-aminomethyl substituted minocycline compounds with various functional groups.
  • Therapeutic Uses: These compounds are intended for treating tetracycline-responsive conditions.
  • Claims: The patent includes composition of matter, method of use, and process claims.
  • Patent Landscape: The antibiotic market is competitive, with many patents filed for tetracycline derivatives.
  • Inventorship: Accurate determination of inventorship is crucial for the patent's validity and enforceability.
  • Strategic Implications: Understanding the patent landscape is vital for licensing, collaboration, and litigation strategies.

FAQs

What are 9-aminomethyl substituted minocycline compounds?

These are chemical derivatives of minocycline with aminomethyl groups attached, designed to enhance therapeutic efficacy and reduce side effects.

What is the current legal status of US Patent 9,365,500?

The patent has expired due to fee-related issues.

How is inventorship determined in US patent law?

Inventorship is determined by identifying those who conceived the definite and permanent idea of the invention and reduced it to practice[2].

What is the purpose of patent landscape analysis?

Patent landscape analysis helps in understanding the competitive landscape, identifying market trends, and extracting legal, business, and technical insights from patent data[3].

Can errors in inventorship be corrected after a patent is issued?

Yes, errors in inventorship can be corrected, but deceptive intent in naming inventors can render the patent unenforceable[2].

Sources

  1. US9365500B2 - 9-aminomethyl substituted minocycline compounds - Google Patents
  2. Determining Inventorship for US Patent Applications - Oregon State University
  3. Navigating Technological Domains with Patent Landscape Analysis - Sagacious Research
  4. Search for patents - USPTO - United States Patent and Trademark Office

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Drugs Protected by US Patent 9,365,500

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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