Details for Patent: 9,493,470
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Which drugs does patent 9,493,470 protect, and when does it expire?
Patent 9,493,470 protects ICLUSIG and is included in one NDA.
This patent has thirty-four patent family members in nine countries.
Summary for Patent: 9,493,470
Title: | Crystalline forms of 3-(imidazo[1,2-B] pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl) methyl]-3-(trifluoromethyl)phenyl}benzamide and its mono hydrochloride salt |
Abstract: | Novel crystalline forms of 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyi-N-{4-[(4-methylpiperazin- -1-yl)methyl]-3-(trifluoromethyl)phenyljbenzamide free base and 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyi-N-{4-[(4-methyl piperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide mono hydrochloride, pharmaceutical compositions thereof and methods of their preparation and use are disclosed herein. The instant application is directed to novel crystalline forms of 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyi-N-{4-[(4-methylpiperazin- -1-yl)methyl]-3-(trifluoromethyl}phenyl}benzamide and 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyi-N-{4-[(4-methylpiperazin- -1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide mono hydrochloride, compositions comprising such crystalline forms, and to methods of their preparation and use. |
Inventor(s): | Murray; Christopher K. (Lexington, MA), Rozamus; Leonard W. (Andover, MA), Chaber; John J. (Westford, MA), Sharma; Pradeep (Westford, MA) |
Assignee: | ARIAD PHARMACEUTICALS, INC. (Cambridge, MA) |
Application Number: | 14/651,577 |
Patent Litigation and PTAB cases: | See patent lawsuits and PTAB cases for patent 9,493,470 |
Patent Claim Types: see list of patent claims | Compound; Composition; Use; |
Drugs Protected by US Patent 9,493,470
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Takeda Pharms Usa | ICLUSIG | ponatinib hydrochloride | TABLET;ORAL | 203469-004 | Dec 18, 2020 | RX | Yes | No | ⤷ Sign Up | ⤷ Sign Up | Y | Y | A METHOD FOR TREATING CHRONIC MYELOID LEUKEMIA | ⤷ Sign Up | ||
Takeda Pharms Usa | ICLUSIG | ponatinib hydrochloride | TABLET;ORAL | 203469-004 | Dec 18, 2020 | RX | Yes | No | ⤷ Sign Up | ⤷ Sign Up | Y | Y | A METHOD FOR TREATING PHILADELPHIA CHROMOSOME POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA | ⤷ Sign Up | ||
Takeda Pharms Usa | ICLUSIG | ponatinib hydrochloride | TABLET;ORAL | 203469-001 | Dec 14, 2012 | RX | Yes | No | ⤷ Sign Up | ⤷ Sign Up | Y | Y | A METHOD FOR TREATING PHILADELPHIA CHROMOSOME POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA | ⤷ Sign Up | ||
Takeda Pharms Usa | ICLUSIG | ponatinib hydrochloride | TABLET;ORAL | 203469-001 | Dec 14, 2012 | RX | Yes | No | ⤷ Sign Up | ⤷ Sign Up | Y | Y | A METHOD FOR TREATING CHRONIC MYELOID LEUKEMIA | ⤷ Sign Up | ||
Takeda Pharms Usa | ICLUSIG | ponatinib hydrochloride | TABLET;ORAL | 203469-003 | Apr 23, 2015 | RX | Yes | No | ⤷ Sign Up | ⤷ Sign Up | Y | Y | A METHOD FOR TREATING PHILADELPHIA CHROMOSOME POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA | ⤷ Sign Up | ||
Takeda Pharms Usa | ICLUSIG | ponatinib hydrochloride | TABLET;ORAL | 203469-003 | Apr 23, 2015 | RX | Yes | No | ⤷ Sign Up | ⤷ Sign Up | Y | Y | A METHOD FOR TREATING CHRONIC MYELOID LEUKEMIA | ⤷ Sign Up | ||
Takeda Pharms Usa | ICLUSIG | ponatinib hydrochloride | TABLET;ORAL | 203469-002 | Dec 14, 2012 | RX | Yes | Yes | ⤷ Sign Up | ⤷ Sign Up | Y | Y | A METHOD FOR TREATING CHRONIC MYELOID LEUKEMIA | ⤷ Sign Up | ||
>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 9,493,470
PCT Information | |||
PCT Filed | December 12, 2013 | PCT Application Number: | PCT/US2013/074571 |
PCT Publication Date: | June 19, 2014 | PCT Publication Number: | WO2014/093579 |
International Family Members for US Patent 9,493,470
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
---|---|---|---|---|---|
Australia | 2013204506 | ⤷ Sign Up | |||
Australia | 2016210725 | ⤷ Sign Up | |||
Australia | 2018201013 | ⤷ Sign Up | |||
Australia | 2019240721 | ⤷ Sign Up | |||
Australia | 2021221493 | ⤷ Sign Up | |||
Australia | 2023219845 | ⤷ Sign Up | |||
Canada | 2815506 | ⤷ Sign Up | |||
>Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |