Details for Patent: 9,708,610

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Summary for Patent: 9,708,610

Scope and claims summary:

Title:	Compositions comprising alternating 2'-modified nucleosides for use in gene modulation
Abstract:	The present invention provides compositions comprising at least one oligomeric compound comprising an alternating motif and further include a region that is complementary to a nucleic acid target. The compositions are useful for targeting selected nucleic acid molecules and modulating the expression of one or more genes. In preferred embodiments the compositions of the present invention hybridize to a portion of a target RNA resulting in loss of normal function of the target RNA. The present invention also provides methods for modulating gene expression.
Inventor(s):	Allerson; Charles (San Diego, CA), Bhat; Balkrishen (Carlsbad, CA), Eldrup; Ann B. (Newtown, CT), Manoharan; Muthiah (Weston, MA), Griffey; Richard H. (Visa, CA), Baker; Brenda F. (Carlsbad, CA), Swayze; Eric E. (Encinitas, CA)
Assignee:	Ionis Pharmaceuticals, Inc. (Carlsbad, CA)
Application Number:	14/834,224
Patent Claim Types: see list of patent claims	Use; Composition; Formulation;

Drugs Protected by US Patent 9,708,610

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