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Last Updated: November 14, 2024

ZIOPTAN Drug Patent Profile


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Which patents cover Zioptan, and what generic alternatives are available?

Zioptan is a drug marketed by Thea Pharma and is included in one NDA. There are two patents protecting this drug and one Paragraph IV challenge.

This drug has eighty-one patent family members in twenty-six countries.

The generic ingredient in ZIOPTAN is tafluprost. There are three drug master file entries for this compound. Four suppliers are listed for this compound. Additional details are available on the tafluprost profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Zioptan

A generic version of ZIOPTAN was approved as tafluprost by MICRO LABS on August 19th, 2019.

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Drug patent expirations by year for ZIOPTAN
Drug Prices for ZIOPTAN

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Pharmacology for ZIOPTAN
Paragraph IV (Patent) Challenges for ZIOPTAN
Tradename Dosage Ingredient Strength NDA ANDAs Submitted Submissiondate
ZIOPTAN Ophthalmic Solution tafluprost 0.0015% 202514 2 2016-02-10

US Patents and Regulatory Information for ZIOPTAN

ZIOPTAN is protected by two US patents.

Patents protecting ZIOPTAN

Method and composition for treating ocular hypertension and glaucoma
Patent Number: ⤷  Sign Up
Patent Expiration: ⤷  Sign Up
Patented Use: REDUCTION OF ELEVATED INTRAOCULAR PRESSURE IN PATIENTS WITH OPEN ANGLE GLAUCOMA OR OCULAR HYPERTENSION

Method and composition for treating ocular hypertension and glaucoma
Patent Number: ⤷  Sign Up
Patent Expiration: ⤷  Sign Up

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Thea Pharma ZIOPTAN tafluprost SOLUTION/DROPS;OPHTHALMIC 202514-001 Feb 10, 2012 AT RX Yes Yes ⤷  Sign Up ⤷  Sign Up Y ⤷  Sign Up
Thea Pharma ZIOPTAN tafluprost SOLUTION/DROPS;OPHTHALMIC 202514-001 Feb 10, 2012 AT RX Yes Yes ⤷  Sign Up ⤷  Sign Up Y ⤷  Sign Up
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

International Patents for ZIOPTAN

When does loss-of-exclusivity occur for ZIOPTAN?

Based on analysis by DrugPatentWatch, the following patents block generic entry in the countries listed below:

Argentina

Patent: 1937
Patent: METODO Y COMPOSICION PARA TRATAR HIPERTENSION OCULAR Y GLAUCOMA QUE COMPRENDE ANALOGOS DE PGF-2ALFA, USO Y METODO PARA AUMENTAR LA SOLUBILIDAD ACUOSA Y MEJORAR LA ESTABILIDAD DE LOS ANALOGOS DE PGF-2ALFA
Estimated Expiration: ⤷  Sign Up

Patent: 0961
Patent: MÉTODO Y COMPOSICIÓN PARA TRATAR HIPERTENSIÓN OCULAR Y GLAUCOMA
Estimated Expiration: ⤷  Sign Up

Australia

Patent: 09252210
Patent: Method and composition for treating ocular hypertension and glaucoma
Estimated Expiration: ⤷  Sign Up

Brazil

Patent: 0913109
Patent: solução aquosa oftálmica, uso de análogos de pgf2a, e, método para aumentar a solubilidade em água e melhorar a estabilidade de análogos de pgf2a em uma solução aquosa oftálmica
Estimated Expiration: ⤷  Sign Up

Canada

Patent: 24194
Patent: PROCEDE ET COMPOSITION UTILISABLES POUR LE TRAITEMENT DE L'HYPERTENSION OCULAIRE ET DU GLAUCOME (METHOD AND COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA)
Estimated Expiration: ⤷  Sign Up

Patent: 65185
Patent: PROCEDE ET COMPOSITION UTILISABLES POUR LE TRAITEMENT DE L'HYPERTENSION OCULAIRE ET DU GLAUCOME (METHOD AND COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA)
Estimated Expiration: ⤷  Sign Up

China

Patent: 2083413
Patent: Method and composition for treating ocular hypertension and glaucoma
Estimated Expiration: ⤷  Sign Up

Croatia

Patent: 0140979
Estimated Expiration: ⤷  Sign Up

Patent: 0170769
Estimated Expiration: ⤷  Sign Up

Patent: 0200998
Estimated Expiration: ⤷  Sign Up

Patent: 0220361
Estimated Expiration: ⤷  Sign Up

Cyprus

Patent: 15565
Estimated Expiration: ⤷  Sign Up

Patent: 20351
Estimated Expiration: ⤷  Sign Up

Denmark

Patent: 06977
Estimated Expiration: ⤷  Sign Up

Patent: 72249
Estimated Expiration: ⤷  Sign Up

Patent: 05334
Estimated Expiration: ⤷  Sign Up

Patent: 14877
Estimated Expiration: ⤷  Sign Up

Eurasian Patent Organization

Patent: 3661
Patent: УПАКОВАННЫЙ РАСТВОР ДЛЯ ЛЕЧЕНИЯ ПОВЫШЕНИЯ ВНУТРИГЛАЗНОГО ДАВЛЕНИЯ И ГЛАУКОМЫ, ВКЛЮЧАЮЩИЙ АНАЛОГ PGF2α (PACKAGED SOLUTION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA, COMPRISING PGF2α ANALOGUE)
Estimated Expiration: ⤷  Sign Up

Patent: 1071413
Patent: СПОСОБ И КОМПОЗИЦИЯ ДЛЯ ЛЕЧЕНИЯ ПОВЫШЕНИЯ ВНУТРИГЛАЗНОГО ДАВЛЕНИЯ И ГЛАУКОМЫ
Estimated Expiration: ⤷  Sign Up

European Patent Office

Patent: 27638
Patent: Procédé et composition pour traiter l'hypertension oculaire et le glaucome (Method and composition for treating ocular hypertension and glaucoma)
Estimated Expiration: ⤷  Sign Up

Patent: 06977
Patent: PROCÉDÉ ET COMPOSITION POUR TRAITER L'HYPERTENSION OCULAIRE ET LE GLAUCOME (METHOD AND COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA)
Estimated Expiration: ⤷  Sign Up

Patent: 72249
Patent: Procédé et composition pour traiter l'hypertension oculaire et le glaucome (Method and composition for treating ocular hypertension and glaucoma)
Estimated Expiration: ⤷  Sign Up

Patent: 05334
Patent: PROCÉDÉ ET COMPOSITION POUR LE TRAITEMENT DE L'HYPERTENSION OCULAIRE ET DU GLAUCOME (METHOD AND COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA)
Estimated Expiration: ⤷  Sign Up

Patent: 14877
Patent: PROCÉDÉ ET COMPOSITION POUR LE TRAITEMENT DE L'HYPERTENSION OCULAIRE ET DU GLAUCOME (METHOD AND COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA)
Estimated Expiration: ⤷  Sign Up

Patent: 35656
Patent: PROCÉDÉ ET COMPOSITION POUR LE TRAITEMENT DE L'HYPERTENSION OCULAIRE ET DU GLAUCOME (METHOD AND COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA)
Estimated Expiration: ⤷  Sign Up

Patent: 89446
Patent: PROCÉDÉ ET COMPOSITION POUR LE TRAITEMENT DE L'HYPERTENSION OCULAIRE ET DU GLAUCOME (METHOD AND COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA)
Estimated Expiration: ⤷  Sign Up

Georgia, Republic of

Patent: 0156220
Patent: COMPOSITION TREATING OCULAR HYPERTENSION AND GLAUCOMA, AND USAGE THEREOF
Estimated Expiration: ⤷  Sign Up

Hungary

Patent: 33103
Estimated Expiration: ⤷  Sign Up

Patent: 49923
Estimated Expiration: ⤷  Sign Up

Patent: 58079
Estimated Expiration: ⤷  Sign Up

Japan

Patent: 48317
Estimated Expiration: ⤷  Sign Up

Patent: 56868
Estimated Expiration: ⤷  Sign Up

Patent: 49992
Estimated Expiration: ⤷  Sign Up

Patent: 89789
Estimated Expiration: ⤷  Sign Up

Patent: 65584
Estimated Expiration: ⤷  Sign Up

Patent: 11521943
Estimated Expiration: ⤷  Sign Up

Patent: 14133765
Patent: METHOD AND COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA
Estimated Expiration: ⤷  Sign Up

Patent: 16065095
Patent: 高眼圧症及び緑内障を治療するための方法及び組成物 (METHOD AND COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA)
Estimated Expiration: ⤷  Sign Up

Patent: 17178957
Patent: 高眼圧症及び緑内障を治療するための方法及び組成物 (METHODS AND COMPOSITIONS FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA)
Estimated Expiration: ⤷  Sign Up

Patent: 18154656
Patent: 高眼圧症及び緑内障を治療するための方法及び組成物 (METHOD AND COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA)
Estimated Expiration: ⤷  Sign Up

Patent: 20073574
Patent: 高眼圧症及び緑内障を治療するための方法及び組成物 (METHOD AND COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA)
Estimated Expiration: ⤷  Sign Up

Patent: 21120412
Patent: 高眼圧症及び緑内障を治療するための方法及び組成物 (METHOD AND COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA)
Estimated Expiration: ⤷  Sign Up

Patent: 23085558
Patent: 高眼圧症及び緑内障を治療するための方法及び組成物 (METHOD AND COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA)
Estimated Expiration: ⤷  Sign Up

Jordan

Patent: 39
Patent: طريقة ومركب لعلاج فرط ضغط العين والجلوكوما (Method and composition for treating ocular hypertension and Glaucoma)
Estimated Expiration: ⤷  Sign Up

Lithuania

Patent: 72249
Estimated Expiration: ⤷  Sign Up

Patent: 05334
Estimated Expiration: ⤷  Sign Up

Patent: 14877
Estimated Expiration: ⤷  Sign Up

Malaysia

Patent: 9463
Patent: METHOD AND COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA
Estimated Expiration: ⤷  Sign Up

Mexico

Patent: 10012987
Patent: METODO Y COMPOSICION PARA TRATAR HIPERTENSION OCULAR Y GLAUCOMA. (METHOD AND COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA.)
Estimated Expiration: ⤷  Sign Up

Poland

Patent: 06977
Estimated Expiration: ⤷  Sign Up

Patent: 72249
Estimated Expiration: ⤷  Sign Up

Patent: 05334
Estimated Expiration: ⤷  Sign Up

Patent: 14877
Estimated Expiration: ⤷  Sign Up

Portugal

Patent: 06977
Estimated Expiration: ⤷  Sign Up

Patent: 72249
Estimated Expiration: ⤷  Sign Up

Patent: 05334
Estimated Expiration: ⤷  Sign Up

Patent: 14877
Estimated Expiration: ⤷  Sign Up

Singapore

Patent: 1628
Patent: METHOD AND COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA
Estimated Expiration: ⤷  Sign Up

Slovenia

Patent: 06977
Estimated Expiration: ⤷  Sign Up

Patent: 72249
Estimated Expiration: ⤷  Sign Up

Patent: 05334
Estimated Expiration: ⤷  Sign Up

Patent: 14877
Estimated Expiration: ⤷  Sign Up

South Korea

Patent: 1650006
Estimated Expiration: ⤷  Sign Up

Patent: 1820816
Estimated Expiration: ⤷  Sign Up

Patent: 1988642
Estimated Expiration: ⤷  Sign Up

Patent: 2114401
Estimated Expiration: ⤷  Sign Up

Patent: 2246598
Estimated Expiration: ⤷  Sign Up

Patent: 110011707
Patent: METHOD AND COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA
Estimated Expiration: ⤷  Sign Up

Patent: 160102319
Patent: 고안압증과 녹내장의 치료 방법 및 조성물 (METHOD AND COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA)
Estimated Expiration: ⤷  Sign Up

Patent: 180008905
Patent: 고안압증과 녹내장의 치료 방법 및 조성물 (METHOD AND COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA)
Estimated Expiration: ⤷  Sign Up

Patent: 190067272
Patent: 고안압증과 녹내장의 치료 방법 및 조성물 (METHOD AND COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA)
Estimated Expiration: ⤷  Sign Up

Patent: 200057801
Patent: 고안압증과 녹내장의 치료 방법 및 조성물 (METHOD AND COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA)
Estimated Expiration: ⤷  Sign Up

Spain

Patent: 95316
Estimated Expiration: ⤷  Sign Up

Patent: 27837
Estimated Expiration: ⤷  Sign Up

Patent: 08050
Estimated Expiration: ⤷  Sign Up

Patent: 07982
Estimated Expiration: ⤷  Sign Up

Taiwan

Patent: 32202
Estimated Expiration: ⤷  Sign Up

Patent: 1000104
Patent: Method and composition for treating ocular hypertension and glaucoma
Estimated Expiration: ⤷  Sign Up

Ukraine

Patent: 2257
Patent: ОФТАЛЬМОЛОГИЧЕСКИЙ ВОДНЫЙ РАСТВОР ДЛЯ ЛЕЧЕНИЯ ГЛАЗНОЙ ГИПЕРТЕНЗИИ И ГЛАУКОМЫ;ОФТАЛЬМОЛОГІЧНИЙ ВОДНИЙ РОЗЧИН ДЛЯ ЛІКУВАННЯ ОЧНОЇ ГІПЕРТЕНЗІЇ ТА ГЛАУКОМИ (OPHTHALMIC AQUEOUS COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA)
Estimated Expiration: ⤷  Sign Up

Generics may enter earlier, or later, based on new patent filings, patent extensions, patent invalidation, early generic licensing, generic entry preferences, and other factors.

See the table below for additional patents covering ZIOPTAN around the world.

Country Patent Number Title Estimated Expiration
Mexico 2010012987 METODO Y COMPOSICION PARA TRATAR HIPERTENSION OCULAR Y GLAUCOMA. (METHOD AND COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA.) ⤷  Sign Up
Eurasian Patent Organization 023661 УПАКОВАННЫЙ РАСТВОР ДЛЯ ЛЕЧЕНИЯ ПОВЫШЕНИЯ ВНУТРИГЛАЗНОГО ДАВЛЕНИЯ И ГЛАУКОМЫ, ВКЛЮЧАЮЩИЙ АНАЛОГ PGF2α (PACKAGED SOLUTION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA, COMPRISING PGF2α ANALOGUE) ⤷  Sign Up
Spain 2968837 ⤷  Sign Up
Portugal 3714877 ⤷  Sign Up
European Patent Office 4035656 PROCÉDÉ ET COMPOSITION POUR LE TRAITEMENT DE L'HYPERTENSION OCULAIRE ET DU GLAUCOME (METHOD AND COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA) ⤷  Sign Up
Singapore 191628 METHOD AND COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA ⤷  Sign Up
>Country >Patent Number >Title >Estimated Expiration

Supplementary Protection Certificates for ZIOPTAN

Patent Number Supplementary Protection Certificate SPC Country SPC Expiration SPC Description
0850926 SPC013/2011 Ireland ⤷  Sign Up SPC013/2011: 20110808, EXPIRES: 20221221
0850926 91943 Luxembourg ⤷  Sign Up 91943, EXPIRES: 20221222
0850926 C00850926/01 Switzerland ⤷  Sign Up PRODUCT NAME: TAFLUPROST; REGISTRATION NO/DATE: SWISSMEDIC 60548 27.01.2010
0850926 300407 Netherlands ⤷  Sign Up 300407, 20171222, EXPIRES: 20221221
0850926 339 Finland ⤷  Sign Up
0850926 11C0020 France ⤷  Sign Up PRODUCT NAME: TAFLUPROST; REGISTRATION NO/DATE IN FRANCE: CIS:6 000 728 O DU 20110328; REGISTRATION NO/DATE AT EEC: 43230 DU 20080430
>Patent Number >Supplementary Protection Certificate >SPC Country >SPC Expiration >SPC Description

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Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.