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Last Updated: December 22, 2024

GENTAMICIN Drug Patent Profile


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Which patents cover Gentamicin, and what generic alternatives are available?

Gentamicin is a drug marketed by Intl Medication, Alpharma Us Pharms, Cosette, Fougera Pharms Inc, Padagis Us, Pharmaderm, Taro, Abbott, Eugia Pharma, Fresenius Kabi Usa, Hikma, Hospira, Kalapharm, Pharm Spec, Solopak, Teva Parenteral, Watson Labs, Wyeth Ayerst, Fera Pharms Llc, Sciegen Pharms Inc, Encube, Alcon Pharms Ltd, Bausch And Lomb, Epic Pharma Llc, Paco, Sandoz, B Braun, and Baxter Hlthcare. and is included in forty-one NDAs.

The generic ingredient in GENTAMICIN is gentamicin sulfate. There are fifteen drug master file entries for this compound. Twenty-seven suppliers are listed for this compound. Additional details are available on the gentamicin sulfate profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Gentamicin

A generic version of GENTAMICIN was approved as gentamicin sulfate by SANDOZ on December 31st, 1969.

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Recent Clinical Trials for GENTAMICIN

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SponsorPhase
Yale UniversityPhase 2
Eye & ENT Hospital of Fudan UniversityN/A
Tanta UniversityN/A

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US Patents and Regulatory Information for GENTAMICIN

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Baxter Hlthcare GENTAMICIN SULFATE IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER gentamicin sulfate INJECTABLE;INJECTION 062373-008 Sep 7, 1982 AP RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Fera Pharms Llc GENTAMICIN SULFATE gentamicin sulfate OINTMENT;OPHTHALMIC 065024-001 Jul 30, 2004 RX No Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Pharm Spec GENTAMICIN SULFATE gentamicin sulfate INJECTABLE;INJECTION 062340-001 Mar 28, 1983 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

GENTAMICIN Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Gentamicin

Introduction to Gentamicin

Gentamicin is a potent aminoglycoside antibiotic widely used to treat severe bacterial infections, including those of the lungs, bones, joints, blood, skin, and urinary tract, as well as meningitis. Its efficacy and broad spectrum of activity make it a crucial component in the fight against bacterial infections.

Market Size and Forecast

The global aminoglycosides market, which includes gentamicin, is projected to grow significantly over the next few years. Here are some key financial metrics:

  • Market Size (Base Year): The global aminoglycosides market was valued at USD 1.68 million in 2022[1].
  • Market Size (Forecast Year): It is expected to reach USD 2.30 million by 2030, indicating a steady growth trajectory[1].
  • CAGR: Although the exact Compound Annual Growth Rate (CAGR) is not specified, the market is anticipated to grow driven by several key factors.

Drivers of Market Growth

Increase in Tuberculosis Cases

The rising incidence of tuberculosis, particularly in low-income countries, is a significant driver for the demand of aminoglycosides like gentamicin. According to the WHO, 1.5 million people died from tuberculosis in 2020, highlighting the urgent need for effective antibiotics in these regions[1].

Increasing Demand for Gentamicin

Gentamicin accounts for the largest market share within the aminoglycosides segment and is expected to maintain its dominance during the forecast period. Its use in treating severe infections caused by bacteria contributes to its high demand[1].

Economic Growth and Antibiotic Consumption

Economic growth, especially in developing countries, has led to increased access and affordability of antibiotics. This trend is expected to continue, driving the consumption of antibiotics, including gentamicin, as people in these regions have better access to healthcare and medications[3].

Market Segmentation

By Drug

  • Gentamicin is the leading drug within the aminoglycosides market, followed by other drugs like neomycin and kanamycin[1].

By Route of Administration

  • Injectable gentamicin is the most common form, but it is also available in topical, oral, and other forms[1].

By Application

  • Gentamicin is used in various applications, including veterinary medicine, skin infections, respiratory diseases, urinary tract infections (UTIs), and pelvic diseases[1].

By End-Users

  • The primary end-users include hospitals, homecare settings, specialty clinics, and others[1].

By Distribution Channel

  • The distribution channels include hospital pharmacies, online pharmacies, and retail pharmacies[1].

Regional Insights

Asia Pacific

  • The Asia Pacific region dominates the antibiotics market, including aminoglycosides like gentamicin, with a market share of over 46% in 2023. This is due to advanced healthcare infrastructure, government initiatives, and the availability of low-cost generic antibiotics[3].

North America and Europe

  • These regions also hold a significant market share, driven by well-established healthcare systems and ongoing research and development in the pharmaceutical sector[3].

Gentamicin Sulfate API Market

Market Size and Growth

  • The Gentamicin Sulfate API Market has experienced rapid growth and is anticipated to continue this trend from 2023 to 2031. The market is segmented by type (above 98%, above 99%) and application (ointment, injection, tablets, granules, others)[4].

Geographical Regions

  • The market is analyzed across various geographical regions, including North America, Europe, Asia-Pacific, South America, and the Middle East and Africa. Asia-Pacific is expected to be a key driver due to its large population and growing healthcare needs[4].

Challenges and Opportunities

Resistance and Fitness Cost

  • The use of gentamicin can lead to the development of resistant bacterial strains, such as small colony variants (SCVs) of Staphylococcus aureus. These SCVs have reduced membrane potential, which affects gentamicin uptake. However, compensatory mutations can restore fitness and membrane potential, highlighting the need for continuous monitoring and adaptation in antibiotic therapy[2].

Innovations and Advancements

  • Innovations in antibiotic therapy and the development of new formulations and delivery methods present opportunities for growth in the gentamicin market. For instance, advancements in injectable and oral forms of gentamicin are expected to enhance its market position[1].

Financial Trajectory

Revenue Projections

  • The global antibiotics market, which includes gentamicin, is projected to grow from USD 53.90 billion in 2024 to USD 85.80 billion by 2033, at a CAGR of 5.3%[3].

Market Share

  • Gentamicin, being a significant part of the aminoglycosides market, is expected to contribute substantially to this revenue growth. Its market share is anticipated to remain high due to its efficacy and widespread use[1].

Key Takeaways

  • Growing Demand: The demand for gentamicin is driven by increasing cases of tuberculosis and other severe bacterial infections.
  • Market Segmentation: The market is segmented by drug type, route of administration, application, end-users, and distribution channels.
  • Regional Dominance: Asia Pacific dominates the market due to its large population and advanced healthcare infrastructure.
  • Challenges: The development of antibiotic-resistant strains and the need for continuous innovation are key challenges.
  • Financial Growth: The market is expected to grow significantly, with the global antibiotics market reaching USD 85.80 billion by 2033.

FAQs

What are the primary drivers of the gentamicin market?

The primary drivers include the increasing incidence of tuberculosis, the growing demand for gentamicin in treating severe bacterial infections, and economic growth leading to increased access to antibiotics.

Which region dominates the gentamicin market?

The Asia Pacific region dominates the gentamicin market due to its advanced healthcare infrastructure and the availability of low-cost generic antibiotics.

What are the challenges associated with gentamicin use?

The challenges include the development of antibiotic-resistant bacterial strains, such as SCVs of Staphylococcus aureus, and the need for continuous innovation to address these resistances.

How is the gentamicin market segmented?

The market is segmented by drug type, route of administration, application, end-users, and distribution channels.

What is the projected growth of the global antibiotics market?

The global antibiotics market is projected to grow from USD 53.90 billion in 2024 to USD 85.80 billion by 2033, at a CAGR of 5.3%.

Sources

  1. Global Aminoglycosides Market – Industry Trends and Forecast to 2030. Data Bridge Market Research.
  2. Novel Pathways for Ameliorating the Fitness Cost of Gentamicin Resistance in Staphylococcus aureus Small Colony Variants. Frontiers in Microbiology.
  3. Antibiotics Market Size to Reach USD 85.80 Billion by 2033. BioSpace.
  4. Gentamicin Sulfate API Market Size, Scope And Forecast Report. Market Research Intellect.

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