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Last Updated: December 22, 2024

PIPERACILLIN Drug Patent Profile


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When do Piperacillin patents expire, and what generic alternatives are available?

Piperacillin is a drug marketed by Istituto Bio Ita Spa, Astral, Eugia Pharma, Eugia Pharma Speclts, Fresenius Kabi, Fresenius Kabi Usa, Hospira Inc, Provepharm Sas, Sagent Pharms Inc, Sandoz, Shandong, Steriscience Speclts, and Wockhardt Bio Ag. and is included in twenty-four NDAs.

The generic ingredient in PIPERACILLIN is piperacillin sodium; tazobactam sodium. There are sixteen drug master file entries for this compound. Seventeen suppliers are listed for this compound. Additional details are available on the piperacillin sodium; tazobactam sodium profile page.

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Scandinavian Critical Care Trials GroupPhase 4
University Hospital, RouenPhase 3
Wake Forest University Health SciencesPhase 4

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US Patents and Regulatory Information for PIPERACILLIN

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Sandoz PIPERACILLIN AND TAZOBACTAM piperacillin sodium; tazobactam sodium INJECTABLE;INJECTION 203557-001 Oct 29, 2014 AP RX No Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Sagent Pharms Inc PIPERACILLIN AND TAZOBACTAM piperacillin sodium; tazobactam sodium INJECTABLE;INJECTION 208674-002 Feb 16, 2021 AP RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Steriscience Speclts PIPERACILLIN AND TAZOBACTAM piperacillin sodium; tazobactam sodium INJECTABLE;INJECTION 065458-003 Aug 15, 2014 AP RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Shandong PIPERACILLIN AND TAZOBACTAM piperacillin sodium; tazobactam sodium INJECTABLE;INJECTION 204959-003 Aug 10, 2018 AP RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Wockhardt Bio Ag PIPERACILLIN AND TAZOBACTAM piperacillin sodium; tazobactam sodium INJECTABLE;INJECTION 206996-001 Mar 22, 2017 AP RX No Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

PIPERACILLIN Market Analysis and Financial Projection Experimental

Piperacillin Sodium Market Dynamics and Financial Trajectory

Introduction to Piperacillin Sodium

Piperacillin sodium is a semisynthetic penicillin antibiotic, widely used in treating serious bacterial infections caused by both gram-positive and gram-negative bacteria. It is often administered in combination with tazobactam, a beta-lactamase inhibitor, to enhance its efficacy against resistant bacterial strains[1].

Market Size and Growth

The global piperacillin sodium market is experiencing significant growth, driven by the increasing demand for effective antibiotics in healthcare settings. Here are some key statistics:

  • The global piperacillin sodium market was estimated at USD 196.92 million in 2021 and is projected to reach USD 209.80 million by 2028, growing at a CAGR of 0.91% during the forecast period[4].
  • The broader penicillin drug market, which includes piperacillin, is expected to reach USD 10.71 billion in 2024 and grow at a CAGR of 3.21% to reach USD 12.55 billion by 2029[3].

Regional Market Dynamics

The market for piperacillin sodium varies significantly across different regions:

  • North America: This region holds a significant market share due to advanced healthcare infrastructure, high healthcare expenditure, and a robust pharmaceutical industry[1].
  • Europe: European countries are focusing on antibiotic stewardship programs, which encourage the appropriate use of antibiotics, thereby boosting demand for effective treatments like piperacillin sodium[1].
  • Asia-Pacific: This region is expected to exhibit the highest growth rate, driven by rising infection rates, increasing healthcare investments, and a growing patient population[1].

Key Drivers of Market Growth

Several factors are driving the growth of the piperacillin sodium market:

  • Increasing Demand for Antibiotics: The rising burden of infectious diseases among the population increases the demand for effective antibiotic treatment options[3].
  • Expansion of Healthcare Infrastructure: Growing investments in healthcare infrastructure, particularly in emerging markets, are leading to increased accessibility to antibiotics[1].
  • Innovations in Drug Formulations: Recent advancements in drug formulations, such as extended-release formulations and combination therapies with beta-lactamase inhibitors, are enhancing the efficacy and safety of piperacillin sodium[1].

Challenges and Restraints

Despite the growth, the market faces several challenges:

  • Antibiotic Resistance: The increasing resistance to antimicrobials poses a significant threat to public health, making infections harder to treat and leading to longer hospital stays, higher medical costs, and increased mortality[1].
  • Stringent Regulatory Frameworks: Regulatory hurdles can slow down the approval and market entry of new antibiotic formulations[3].

Financial Trajectory and Investment Opportunities

The financial trajectory of the piperacillin sodium market is promising, with several investment opportunities:

  • Research and Development: Investing in R&D for new formulations and delivery mechanisms can yield high returns as the demand for effective antibiotics continues to rise[1].
  • Manufacturing Capabilities: Expanding manufacturing facilities to meet increased demand can benefit companies through economies of scale, leading to improved profitability[1].
  • Emerging Markets: Investing in emerging markets, particularly in Asia-Pacific and Latin America, offers substantial growth potential due to rising healthcare needs and increasing access to antibiotics[1].

Generic Alternatives and Market Accessibility

As patents for branded piperacillin sodium products expire, the market is witnessing a surge in generic alternatives. This shift is expected to make the drug more accessible and affordable, particularly in low- and middle-income countries[1].

Collaborations and Partnerships

Collaborations between pharmaceutical companies and healthcare institutions are becoming increasingly common. These partnerships aim to facilitate research and development efforts, improve antibiotic stewardship, and enhance education on appropriate antibiotic usage among healthcare professionals[1].

Market Forecast and Projections

The market for piperacillin sodium is forecasted to continue its growth trajectory:

  • The Asia-Pacific region is expected to grow at the highest CAGR over the forecast period, driven by rising infection rates and increasing healthcare investments[3].
  • The combination of broad-spectrum penicillins with other classes of drugs is likely to increase the demand for these products, thereby propelling market growth[3].

Key Players in the Market

Several major pharmaceutical companies are key players in the piperacillin sodium market:

  • Qilu Pharmaceutical
  • Pfizer Healthcare
  • Fresenius Kabi AG
  • Aurobindo Pharma
  • Sandoz Inc
  • Novartis AG
  • GSK plc
  • Lupin Limited[4][5].

Impact of COVID-19

The COVID-19 pandemic had an initial adverse impact on the antibiotic drug market due to production shutdowns, export restrictions, and service interruptions. However, research activities on penicillin derivatives, including their potential as SARS-CoV-2 main protease inhibitors, are expected to positively impact the market in the coming years[3].

Key Takeaways

  • The piperacillin sodium market is driven by increasing demand for effective antibiotics and expanding healthcare infrastructure.
  • Innovations in drug formulations and the rise of generic alternatives are key growth drivers.
  • The Asia-Pacific region is expected to exhibit the highest growth rate.
  • Antibiotic resistance and stringent regulatory frameworks are significant challenges.
  • Investment opportunities lie in R&D, manufacturing capabilities, and emerging markets.

Frequently Asked Questions (FAQs)

What is the current market size of the piperacillin sodium market?

The global piperacillin sodium market was estimated at USD 196.92 million in 2021[4].

What is the projected growth rate of the piperacillin sodium market?

The market is projected to grow at a CAGR of 0.91% from 2021 to 2028[4].

Which region is expected to grow the fastest in the piperacillin sodium market?

The Asia-Pacific region is expected to grow at the highest CAGR over the forecast period[3].

What are the main challenges facing the piperacillin sodium market?

The main challenges include antibiotic resistance and stringent regulatory frameworks[1][3].

Who are the key players in the piperacillin sodium market?

Key players include Qilu Pharmaceutical, Pfizer Healthcare, Fresenius Kabi AG, Aurobindo Pharma, and Sandoz Inc[4].

Cited Sources

  1. Market Research Intellect: "Piperacillin Sodium Market Size And Projection"
  2. Oxford University Press: "Anti-infective Acquisition Costs for a Stewardship Program"
  3. Mordor Intelligence: "Penicillin Drug Market Report | Industry Analysis, Size & Forecast"
  4. Business Wire: "Global Piperacillin Sodium (CAS 59703 84 3) Market Report 2022"
  5. Global Banking and Finance: "Insightful Analysis of Piperacillin and Tazobactam Market 2021-2027"

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