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Patent: 10,004,792


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Summary for Patent: 10,004,792
Title:Peptides and combination of peptides for use in immunotherapy against various cancers
Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
Inventor(s): Mahr; Andrea (Tuebingen, DE), Weinschenk; Toni (Aichwald, DE), Song; Colette (Ostfildern, DE), Schoor; Oliver (Tuebingen, DE), Fritsche; Jens (Dusslingen, DE), Singh; Harpreet (Houston, TX)
Assignee: IMMATICS BIOTECHNOLOGIES GMBH (Tuebingen, DE)
Application Number:15/374,993
Patent Claims:see list of patent claims
Patent landscape, scope, and claims summary:

Comprehensive Analysis of United States Patent 10,004,792: Navigating the Complexities of Patent Eligibility and Landscape

Introduction

Understanding the intricacies of a patent, particularly one like United States Patent 10,004,792, involves a multifaceted analysis that delves into patent eligibility, the patent landscape, and the strategic implications of such a patent. This article will provide a detailed examination of these aspects, highlighting key considerations and challenges.

Patent Eligibility Under 35 U.S.C. § 101

Patent eligibility is a critical factor in the validity and enforceability of any patent. For patents like 10,004,792, the subject matter eligibility analysis under 35 U.S.C. § 101 is paramount.

The Alice/Mayo Test

The Alice/Mayo test is a two-step framework used to determine whether a patent claim is eligible for patent protection. The first step involves determining whether the claim is directed to a law of nature, natural phenomenon, or abstract idea. If it is, the second step evaluates whether the claim contains an "inventive concept" that transforms the nature of the claim into something significantly more than the ineligible concept itself[2].

Prong Two of Step 2A

For AI inventions and other complex technologies, Prong Two of Step 2A is particularly important. This prong requires demonstrating that the claim elements beyond those corresponding to the alleged abstract idea integrate the abstract idea into a practical application. This can be shown by highlighting improvements in the functioning of a computer or another technical field[1].

Crafting Effective Arguments Under Prong Two

When facing section 101 rejections, it is crucial to build a compelling narrative around the main novelty of the claimed invention. This involves identifying the unique aspects of the invention and framing them within a broader context that emphasizes their practical utility and real-world impact. The argument must be supported by the specification and guide the examiner through a clear and logical progression from the technical problem to the claimed innovation[1].

Understanding the Patent Examiner's Perspective

The approach of the assigned patent examiner can significantly influence the outcome of the patent eligibility analysis. Different examiners may apply the framework differently, so understanding their specific approach is vital. For instance, some examiners may require improvements to the functioning of a computer, while others may accept improvements in other technical fields[1].

The Role of the Patent Trial and Appeal Board (PTAB)

The PTAB plays a significant role in the patent landscape, particularly in challenging the validity of patents. Created by the Leahy-Smith America Invents Act (AIA), PTAB provides a more efficient and cost-effective means to adjudicate patent validity issues compared to federal court litigation.

Inter Partes Review (IPR) and Post-Grant Review (PGR)

IPR and PGR are administrative challenges that can be used to invalidate patents. These procedures are faster and less expensive than federal court litigation and require a lower standard of proof. However, they also introduce complexities, such as the need to overcome a presumption of validity and the potential for inconsistent application of the law by different PTAB panels[2].

Patent Landscape Analysis

A comprehensive patent landscape analysis is essential for understanding the strategic position of a patent like 10,004,792 within its technological field.

Identifying Saturation and Trends

Patent landscape analysis helps in identifying high saturation areas within a technology field and uncovering trends that might otherwise be missed. This analysis can guide business and R&D management in making long-term decisions about where to focus their inventive efforts and how to navigate around existing patents[3].

Competitor Analysis

Going beyond known competitors, a thorough patent landscape analysis can reveal niche technologies and areas where competitors are focusing their resources. For example, a company might have a small number of patents in a specific niche but these patents could represent a significant portion of their overall portfolio, indicating a strategic focus[3].

Determining Inventorship

Proper inventorship is crucial for the validity of a patent. Inventorship determination focuses on the conception step, requiring the identification of each person who conceived the idea or ideas of the patent claims.

Conception and Reduction to Practice

Conception is defined as the formation in the mind of the inventor of a definite and permanent idea of the complete and operative invention. This idea must be sufficiently definite and permanent to permit one with ordinary skill in the field to reduce it to practice without undue experimentation[4].

Strategic Implications and Challenges

Navigating PTAB Challenges

For patents facing challenges at PTAB, the process can be complex and challenging. The heightened standards and specific requirements, such as the need to access and sequence seed deposits in certain cases, can pose significant hurdles for challengers and patent owners alike[5].

Balancing Patent Protection and Competition

The patent system aims to balance the protection of intellectual property with the promotion of competition and innovation. However, the application of patent policies can sometimes lead to unintended consequences, such as reducing competition in certain markets. For instance, the requirement for seed deposits in plant utility patents can unnecessarily restrict competition among farmers[5].

Key Takeaways

  • Patent Eligibility: Ensuring that a patent claim integrates an abstract idea into a practical application is crucial for overcoming section 101 rejections.
  • Patent Examiner Understanding: Knowing how the assigned patent examiner applies the subject matter eligibility analysis is vital for developing a successful strategy.
  • PTAB Procedures: PTAB offers a faster and less expensive alternative to federal court litigation but introduces its own set of complexities and challenges.
  • Patent Landscape Analysis: This analysis is essential for strategic decision-making and navigating the competitive landscape.
  • Inventorship Determination: Accurate determination of inventorship is critical for the validity and enforceability of a patent.

FAQs

What is the significance of Prong Two of Step 2A in patent eligibility analysis?

Prong Two of Step 2A is crucial for demonstrating that a patent claim integrates an abstract idea into a practical application, which can be shown by highlighting improvements in the functioning of a computer or another technical field[1].

How does PTAB differ from federal court litigation in challenging patent validity?

PTAB procedures are generally faster, less expensive, and use a lower standard of proof compared to federal court litigation. However, they also have specific requirements and can be influenced by different panels and examiners[2].

What is the purpose of a patent landscape analysis?

A patent landscape analysis helps in identifying high saturation areas, uncovering trends, and guiding long-term decisions about where to focus inventive efforts. It also aids in competitor analysis and strategic planning[3].

How is inventorship determined in a patent application?

Inventorship determination focuses on the conception step, requiring the identification of each person who conceived the idea or ideas of the patent claims. Conception must be definite and permanent, allowing one with ordinary skill in the field to reduce it to practice without undue experimentation[4].

What are the challenges posed by PTAB's heightened standards in plant utility patents?

The heightened standards, such as the requirement for seed deposits, can pose significant hurdles for challengers and patent owners, potentially reducing competition in seed markets and imposing unnecessary restrictions on farmers[5].

Sources

  1. The Importance of Prong Two of Step 2A for AI Inventions - Baker Botts
  2. The Patent Trial and Appeal Board and Inter Partes Review - Congressional Research Service
  3. Patent Landscape Analysis - Uncovering Strategic Insights - AcclaimIP
  4. Determining Inventorship for US Patent Applications - Oregon State University
  5. Director Review Petitions Charge PTAB Analysis of Plant Utility Claims Threatens Competition for U.S. Farmers - IPWatchdog

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Details for Patent 10,004,792

ApplicantTradenameBiologic IngredientDosage FormBLAApproval DatePatent No.Expiredate
Genentech, Inc. AVASTIN bevacizumab Injection 125085 February 26, 2004 10,004,792 2035-12-11
>Applicant>Tradename>Biologic Ingredient>Dosage Form>BLA>Approval Date>Patent No.>Expiredate
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