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Last Updated: December 23, 2024

Patent: 8,431,124


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Summary for Patent: 8,431,124
Title:Methods for treating a disease characterized by an excess of hyaluronan by administering a soluble hyaluronidase glycoprotein (sHASEGP)
Abstract: Provided are soluble neutral active Hyaluronidase Glycoproteins (sHASEGP\'s), methods of manufacture, and their use to facilitate administration of other molecules or to alleviate glycosaminoglycan associated pathologies. Minimally active polypeptide domains of the soluble, neutral active sHASEGP domains are described that include asparagine-linked sugar moieties required for a functional neutral active hyaluronidase domain. Included are modified amino-terminal leader peptides that enhance secretion of sHASEGP. Sialated and pegylated forms of the sHASEGPs also are provided. Methods of treatment by administering sHASEGPs and modified forms thereof also are provided.
Inventor(s): Bookbinder; Louis H. (San Diego, CA), Kundu; Anirban (San Diego, CA), Frost; Gregory I. (Del Mar, CA)
Assignee: Halozyme, Inc. (San Diego, CA)
Application Number:12/386,473
Patent Claims:see list of patent claims
Patent landscape, scope, and claims summary:

Comprehensive Analysis of the Claims and Patent Landscape for United States Patent 8,431,124

Introduction

United States Patent 8,431,124, while specific in its claims, exists within a broader patent landscape that is crucial for understanding its validity, potential challenges, and strategic implications. This analysis will delve into the claims of the patent, the surrounding patent landscape, and the tools and strategies used to evaluate and navigate this complex environment.

Overview of the Patent

Patent Details

United States Patent 8,431,124, though not explicitly detailed in the provided sources, typically involves a specific invention or innovation. To analyze this patent, one must review its claims, which define the scope of the invention and the rights granted to the patent holder.

Claims Analysis

The claims section of a patent is critical as it outlines what the patent protects. Here, each claim must be novel, non-obvious, and directed to patent-eligible subject matter to be valid[1].

  • Novelty Requirement: The claimed invention must be new and not previously disclosed in the prior art. This involves ensuring that every element of the claimed invention is not already available to the public before the effective filing date of the patent application[1].
  • Nonobviousness Requirement: The invention must be significantly different from existing knowledge and not obvious to a person of ordinary skill in the relevant field. This requires demonstrating that the invention is more than a combination of existing elements[1].
  • Patent-Eligible Subject Matter: The claims must not be directed to ineligible subject matter such as laws of nature, natural phenomena, or abstract ideas unless they contain an inventive concept that transforms the nature of the claim[1].

Patent Landscape Analysis

Importance of Patent Landscape Analysis

Patent landscape analysis is essential for understanding the broader context in which a patent exists. This analysis helps in identifying the saturation level of a specific technology area, competitors, and potential risks or opportunities[2].

Saturated Patent Spaces

If the technology area of Patent 8,431,124 is highly saturated, it may be challenging to secure broad claims. A comprehensive patent landscape analysis can reveal high saturation levels and guide decisions on whether to continue research and development in that area or pivot to newer, less crowded spaces[2].

Going Beyond Known Competitors

A thorough patent landscape analysis involves searching beyond direct competitors. This approach helps in uncovering potential competitors, emerging technologies, and market trends that might not be immediately apparent from narrow searches focused on known competitors[2].

Tools and Strategies for Patent Analysis

Advanced Search Techniques

Using advanced tools and strategies is crucial for conducting comprehensive patent searches. Here are some key methods:

  • AI and Precision Search Technology: AI algorithms can enhance search efficiency by identifying relevant results that might have been missed. Advanced search platforms can process vast amounts of data quickly and accurately[3].
  • Patent Family Searching: Understanding related patents within a family is vital. This involves searching across different jurisdictions and handling variations in claims that may arise during the prosecution process[3].
  • Custom Alerts: Setting up alerts for new patent applications or changes to existing patents helps in staying updated with the evolving patent landscape. This is particularly important given the high volume of new patent applications filed annually[3].

Inter Partes Review (IPR) and Post-Grant Review (PGR)

Challenges to Patent Validity

Patents like 8,431,124 can be challenged through administrative proceedings such as Inter Partes Review (IPR) and Post-Grant Review (PGR) before the Patent Trial and Appeal Board (PTAB). These proceedings offer a faster and less expensive alternative to judicial proceedings for challenging patent validity[1].

  • PTAB Process: IPRs and PGRs are decided by a panel of three administrative patent judges. These proceedings require a lower burden of proof (preponderance of the evidence) compared to judicial proceedings (clear and convincing evidence)[1].
  • Strategic Implications: Entities accused of patent infringement often use IPR or PGR to challenge the validity of patents asserted against them. This can be a strategic move to invalidate patents that may be overly broad or invalid[1].

Competitor Benchmarking and Portfolio Optimization

Using IP Analytics Tools

Tools like PatentSight from LexisNexis IP Solutions provide actionable insights into patent portfolios. These tools help in assessing the value or risk of acquisition candidates, analyzing portfolios for technological fit, and identifying key patents[5].

  • Patent Asset Index: This index offers an objective measure of global technological strength and impact, helping in evaluating the quality of a patent portfolio[5].
  • Customized Technology Definitions: Enhancing competitor benchmarking by leveraging personalized views of specialized technology areas can provide strategic advantages[5].

Sustainability and Technological Fit

Mapping Patents to UN SDGs

Conducting patent analyses against the United Nations Sustainable Development Goals (UN SDGs) can provide insights into the sustainability and societal impact of the patented technology. This approach helps in aligning R&D efforts with broader global objectives[5].

Key Takeaways

  • Claims Analysis: The validity of a patent hinges on its claims being novel, non-obvious, and directed to patent-eligible subject matter.
  • Patent Landscape Analysis: Understanding the broader patent landscape is crucial for strategic decision-making and identifying potential risks and opportunities.
  • Advanced Search Techniques: Leveraging AI, patent family searching, and custom alerts can enhance the efficiency and comprehensiveness of patent searches.
  • IPR and PGR: These administrative proceedings offer a faster and less expensive way to challenge patent validity compared to judicial proceedings.
  • Competitor Benchmarking: Using IP analytics tools helps in evaluating patent portfolios and identifying key patents and technological trends.

FAQs

What is the significance of the Patent Trial and Appeal Board (PTAB) in patent law?

The PTAB, created by the Leahy-Smith America Invents Act (AIA), is a tribunal within the USPTO that hears administrative challenges to the validity of patents, including IPR and PGR. This provides a faster and less expensive alternative to judicial proceedings for challenging patent validity[1].

How does patent landscape analysis help in making strategic decisions?

Patent landscape analysis helps in determining the saturation level of a technology area, identifying competitors, and uncovering potential risks or opportunities. This guides decisions on whether to invest in or develop new technologies[2].

What are the key differences between IPR and PGR?

Both IPR and PGR are administrative proceedings before the PTAB, but PGR has a broader scope and can be used to challenge patents on more grounds than IPR. IPR is generally used for challenging patents based on prior art, while PGR can also challenge patents based on other grounds such as written description and enablement[1].

How can AI tools enhance patent searching?

AI tools can improve the efficiency of patent searches by pulling in relevant results that may have been missed, processing vast amounts of data quickly, and providing more accurate results[3].

What is the role of the Patent Asset Index in evaluating patent portfolios?

The Patent Asset Index provides an objective measure of global technological strength and impact, helping in evaluating the quality and value of a patent portfolio[5].

More… ↓

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Details for Patent 8,431,124

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Bausch & Lomb Incorporated VITRASE hyaluronidase Injection 021640 May 05, 2004 ⤷  Subscribe 2023-03-05
Bausch & Lomb Incorporated VITRASE hyaluronidase Injection 021640 December 02, 2004 ⤷  Subscribe 2023-03-05
Amphastar Pharmaceuticals, Inc. AMPHADASE hyaluronidase Injection 021665 October 26, 2004 ⤷  Subscribe 2023-03-05
Akorn, Inc. HYDASE hyaluronidase Injection 021716 October 25, 2005 ⤷  Subscribe 2023-03-05
Halozyme Therapeutics, Inc. HYLENEX RECOMBINANT hyaluronidase human Injection 021859 December 02, 2005 ⤷  Subscribe 2023-03-05
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

International Patent Family for US Patent 8,431,124

Country Patent Number Estimated Expiration
South Africa 200707898 ⤷  Subscribe
South Africa 200507978 ⤷  Subscribe
World Intellectual Property Organization (WIPO) 2006091871 ⤷  Subscribe
World Intellectual Property Organization (WIPO) 2004078140 ⤷  Subscribe
United States of America 9677062 ⤷  Subscribe
United States of America 9677061 ⤷  Subscribe
>Country >Patent Number >Estimated Expiration

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