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Last Updated: December 24, 2024

Patent: 5,236,838


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Summary for Patent: 5,236,838
Title: Enzymatically active recombinant glucocerebrosidase
Abstract:Recombinant enzymatically active glucocerebrosidase is produced by a eukaryotic cell. Also, a cell includes nucleic acid encoding enzymatically active glucocerebrosidase; also a eukaryotic organism contains such a cell. Also, a method for producing enzymatically active glucocerebrosidase includes steps of introducing glucocerebrosidase-encoding nucleic acid into a eukaryotic cell, causing the cell to express glucocerebrosidase, and purifying the glucocerebrosidase from the cell.
Inventor(s): Rasmussen; James (Boston, MA), Barsomian; Gary (Georgetown, MA), Bergh; Michel (Belmont, MA)
Assignee: Genzyme Corporation (Cambridge, MA)
Application Number:07/748,283
Patent Claims:see list of patent claims
Patent landscape, scope, and claims summary:

Analyzing the Claims and Patent Landscape of United States Patent 5,236,838

Introduction

United States Patent 5,236,838, though not directly provided in the sources, can be analyzed within the context of patent law, the patent landscape, and the broader implications of patent claims. Here, we will delve into the general principles of patent law, the process of patent landscaping, and the critical analysis of patent claims, using relevant examples and principles to illustrate the points.

Understanding Patent Law and Claims

What are Patents?

Patents are exclusive rights granted to inventors for their inventions, allowing them to exclude others from making, using, or selling the invention for a specified period. In the United States, this right is codified under 35 U.S.C. § 271(a), which includes the making, using, or selling of the invention or its importation into the U.S.[1].

Purpose of Patents

The primary purpose of patents is to promote scientific progress and useful arts by securing exclusive rights to inventors for limited times. This is based on the "exchange-for-secrets" thesis, where inventors disclose their inventions to society in exchange for monopoly rights[1].

The Patent Landscape

Identifying Technology Clusters

Patent landscaping involves identifying and analyzing patents related to specific technologies. This can be done through automated methods that expand from a seed set of patents to broader technological classes and citations. The process often involves pruning out false positives using classification models trained on patent abstracts[3].

Key Players and Technologies

In analyzing a patent landscape, it is crucial to identify top assignees and inventors, as well as the technological classes that are overrepresented. This helps in understanding the market dominance and innovation trends within a particular field[3].

Critical Analysis of Patent Claims

Claim Structure and Scope

Patent claims define the scope of the invention and are critical in determining the exclusivity granted to the inventor. Claims must be clear, concise, and supported by the patent's specification. The breadth and specificity of claims can significantly impact the patent's enforceability and value[1].

Examples from Similar Patents

For instance, patents related to biotechnological innovations, such as those involving recombinant proteins, often have complex claim structures. These claims might include methods for improving protein production using pharmacological chaperones, which are detailed in patents like US9206457[5].

Legal and Economic Implications

The claims in a patent can have significant legal and economic implications. For example, the incentive-to-invent theory suggests that patents are necessary to compensate inventors for their investment in time, money, and effort. However, critics argue that many patents may not provide sufficient information for others to use the technology without additional research and development[1].

Case Study: Analyzing a Biotech Patent

Patent 5,236,838 Context

While the specific details of Patent 5,236,838 are not provided, we can infer its analysis based on similar biotech patents. For example, patents in the biotech field often involve complex biological processes and require detailed claims to protect the invention.

Claim Analysis

  • Claim Scope: The claims would need to be specific enough to cover the invention but broad enough to prevent easy circumvention. For biotech patents, this might involve claims on specific methods, compositions, or uses.
  • Support from Specification: The claims must be fully supported by the specification, which includes a detailed description of the invention and how to make and use it.
  • Novelty and Non-Obviousness: The claims must meet the criteria of novelty and non-obviousness, ensuring that the invention is new and not an obvious extension of existing knowledge.

Economic and Legal Impact

  • Market Exclusivity: The patent would grant the inventor exclusive rights, allowing them to control the market for the invention.
  • Innovation Incentives: The patent would incentivize further innovation by providing a return on investment for the inventor.
  • Litigation and Enforcement: The clarity and scope of the claims would be crucial in any litigation or enforcement actions, as they define the boundaries of the inventor’s rights.

Challenges and Critiques

Information Disclosure

One critique of the patent system is that many patents do not provide sufficient information for others to use the technology without additional research. This can hinder the progress of science and innovation rather than promote it[1].

Overlapping Patents

The patent landscape can be complex, with multiple patents covering similar technologies. This can lead to patent thickets, where overlapping patents create barriers to innovation rather than incentives[3].

Key Takeaways

  • Patent Claims: Clear and specific claims are essential for defining the scope of the invention and ensuring enforceability.
  • Patent Landscape: Understanding the broader patent landscape helps in identifying key players, technologies, and market trends.
  • Economic and Legal Implications: Patents have significant economic and legal implications, including market exclusivity, innovation incentives, and potential litigation.
  • Critiques and Challenges: The patent system faces critiques regarding information disclosure and the complexity of overlapping patents.

FAQs

What is the primary purpose of patents?

The primary purpose of patents is to promote scientific progress and useful arts by securing exclusive rights to inventors for limited times.

How are patent claims structured?

Patent claims must be clear, concise, and supported by the patent's specification. They define the scope of the invention and are critical in determining the exclusivity granted to the inventor.

What is the significance of patent landscaping?

Patent landscaping helps in identifying and analyzing patents related to specific technologies, identifying key players, and understanding market trends and innovation hotspots.

What are some critiques of the patent system?

Critiques include the argument that many patents do not provide sufficient information for others to use the technology without additional research and the complexity of overlapping patents that can hinder innovation.

How do patents impact innovation?

Patents can incentivize innovation by providing a return on investment for inventors, but they can also create barriers if the claims are too broad or if there are overlapping patents.

Sources

  1. Heled, Y. (2010). Patents vs. Statutory Exclusivities in Biological Pharmaceuticals. DePaul University College of Law.
  2. Google Patents. (n.d.). Utilization of pharmacological chaperones to improve manufacturing. EP2435459B1.
  3. PLOS ONE. (2023). Identifying technology clusters based on automated patent analysis. 10.1371/journal.pone.0295587.
  4. Google Patents. (2019). HIGH CONCENTRATION ALPHA-GLUCOSIDASE COMPOSITIONS FOR THE TREATMENT OF POMPE DISEASE. US10512677.
  5. Google Patents. (n.d.). Methods for improving the production of recombinant proteins through the use of pharmacological chaperones. US9206457.

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Details for Patent 5,236,838

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genzyme Corporation CEREZYME imiglucerase For Injection 020367 May 23, 1994 5,236,838 2010-08-17
Genzyme Corporation CEREZYME imiglucerase For Injection 020367 September 22, 1999 5,236,838 2010-08-17
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

International Patent Family for US Patent 5,236,838

Country Patent Number Estimated Expiration
World Intellectual Property Organization (WIPO) 9007573 ⤷  Subscribe
United States of America 6451600 ⤷  Subscribe
United States of America 5549892 ⤷  Subscribe
United States of America 2005026249 ⤷  Subscribe
United States of America 2005019861 ⤷  Subscribe
United States of America 2002168750 ⤷  Subscribe
Japan H03503721 ⤷  Subscribe
>Country >Patent Number >Estimated Expiration

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