BOTOX COSMETIC Drug Profile

Summary for Tradename: BOTOX COSMETIC

High Confidence Patents:	11
Applicants:	1
BLAs:	1
Drug Prices:	Drug price information for BOTOX COSMETIC
Recent Clinical Trials:	See clinical trials for BOTOX COSMETIC

See drug prices for BOTOX COSMETIC

Recent Clinical Trials for BOTOX COSMETIC

Identify potential brand extensions & biosimilar entrants

Sponsor	Phase
Food and Drug Administration (FDA)	Phase 1
Spaulding Clinical Research LLC	Phase 1
Assiut University	Phase 1

See all BOTOX COSMETIC clinical trials

Pharmacology for BOTOX COSMETIC

Mechanism of Action	Acetylcholine Release Inhibitors
Physiological Effect	Neuromuscular Blockade
Established Pharmacologic Class	Acetylcholine Release Inhibitor Neuromuscular Blocker

Note on Biologic Patents

Matching patents to biologic drugs is far more complicated than for small-molecule drugs.

DrugPatentWatch employs three methods to identify biologic patents:

1. Brand-side disclosures in response to biosimilar applications

These patents were identified from disclosures by the brand-side company, in response to a potential biosimilar seeking to launch. They have a high certainty of blocking biosimilar entry. The expiration dates listed are not estimates — they're expiration dates as indicated by the brand-side company.

2. General brand-side disclosures

These patents were identified from searching drug labels and other general disclosures from the brand-side company. This list may exclude some of the patents which block biosimilar launch, and some of these patents listed may not actually block biosimilar launch. The expiration dates listed for these patents are estimates, based on the grant date of the patent.

3. Patents from broad patent text search

For completeness, these patents were identified by searching the patent literature for mentions of the branded or ingredient name of the drug. Some of these patents protect the original drug, whereas others may protect follow-on inventions or even inventions casually mentioning the drug. The expiration dates listed for these patents are estimates, based on the grant date of the patent.

1) High Certainty: US Patents for BOTOX COSMETIC Derived from Brand-Side Litigation

No patents found based on brand-side litigation

2) High Certainty: US Patents for BOTOX COSMETIC Derived from Company Disclosures

These patents were obtained from company disclosures

Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Patent No.	Estimated Patent Expiration	Source
Abbvie Inc.	BOTOX COSMETIC	onabotulinumtoxina	For Injection	103000	6,667,041	2017-07-15	Company disclosures
Abbvie Inc.	BOTOX COSMETIC	onabotulinumtoxina	For Injection	103000	6,683,049	2013-12-28	Company disclosures
Abbvie Inc.	BOTOX COSMETIC	onabotulinumtoxina	For Injection	103000	6,896,886	2013-12-28	Company disclosures
Abbvie Inc.	BOTOX COSMETIC	onabotulinumtoxina	For Injection	103000	6,974,578	2013-12-28	Company disclosures
Abbvie Inc.	BOTOX COSMETIC	onabotulinumtoxina	For Injection	103000	7,001,602	2017-07-15	Company disclosures

3) Low Certainty: US Patents for BOTOX COSMETIC Derived from Patent Text Search

These patents were obtained by searching patent claims

Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Patent No.	Estimated Patent Expiration	Source
Abbvie Inc.	BOTOX COSMETIC	onabotulinumtoxina	For Injection	103000	10,016,338	2033-03-11	Patent claims search
Abbvie Inc.	BOTOX COSMETIC	onabotulinumtoxina	For Injection	103000	10,039,910	2039-02-26	Patent claims search
Abbvie Inc.	BOTOX COSMETIC	onabotulinumtoxina	For Injection	103000	10,149,893	2039-02-26	Patent claims search
Abbvie Inc.	BOTOX COSMETIC	onabotulinumtoxina	For Injection	103000	10,206,743	2034-03-16	Patent claims search
Abbvie Inc.	BOTOX COSMETIC	onabotulinumtoxina	For Injection	103000	10,226,550	2036-03-11	Patent claims search

International Patents for BOTOX COSMETIC

Country	Patent Number	Estimated Expiration
Japan	2018090633
Hong Kong	1080377
Japan	2007091756
Australia	2005234633
Germany	69434540

Supplementary Protection Certificates for BOTOX COSMETIC

Supplementary Protection Certificate	SPC Country	SPC Expiration	SPC Description
C02145629/01	Switzerland		FORMER OWNER: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE, US
122013000060	Germany		PRODUCT NAME: BOTULINUMTOXIN; NAT. REGISTRATION NO/DATE: IE/H/0113/001-003/II/077 20130131; FIRST REGISTRATION: FINNLAND IE/H/0113/001-003/II/077-FI 20130116
300563	Netherlands		DETAILS ASSIGNMENT: VERANDERING VAN EIGENAAR(S), OVERDRACHT
122008000042	Germany		PRODUCT NAME: CLOSTRIDIUM BOTULINUM NEUROTOXIN TYP A (150KD), FREI VON KOMPLEXPROTEINEN; REGISTRATION NO/DATE: 57093.00.00 20050531
C300564	Netherlands		PRODUCT NAME: BOTULINUM TOXINE; NAT. REGISTRATION NO/DATE: RVG 32957RVG 17379RVG 32958 2012270627; FIRST REGISTRATION: NL 25449 20110822

BOTOX COSMETIC Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for BOTOX Cosmetic

Introduction to BOTOX Cosmetic

BOTOX Cosmetic, a form of botulinum toxin, has become a cornerstone in the aesthetic and therapeutic industries. Its widespread use in cosmetic procedures and therapeutic applications has driven significant market growth. Here, we delve into the market dynamics and financial trajectory of BOTOX Cosmetic.

Market Size and Growth

The global BOTOX market, which includes both cosmetic and therapeutic applications, was valued at USD 6.4 billion in 2022. It is projected to grow at a Compound Annual Growth Rate (CAGR) of 11.50% from 2022 to 2030, reaching USD 15.2 billion by 2030[1].

Geographical Analysis

North America

North America dominates the global BOTOX market, holding a significant market share of 34.17% in 2022. This dominance is attributed to high awareness levels about therapeutic procedures and non-surgical aesthetics, as well as advanced technological infrastructure[1].

Europe

Europe is the second-largest market for BOTOX, driven by an expanding geriatric population and increasing demand for aesthetic treatments. The region is expected to continue its growth trajectory over the forecast period[1].

Asia Pacific

The Asia Pacific region is also experiencing rapid growth due to the increasing adoption of non-surgical botulinum toxin methods among the aging population and favorable government regulations[1].

Key Drivers of Market Growth

Increasing Demand for Aesthetic Procedures

The growing focus on physical appearance and aesthetics is a significant driver. Consumers are increasingly opting for non-invasive and minimally invasive cosmetic treatments, which has boosted the demand for BOTOX Cosmetic[1][3].

Technological Advancements

Advancements in cosmetic surgeries, including computer-assisted surgery and 3D printing, have made treatments more accurate and reduced recovery times, further driving market growth[3].

Therapeutic Applications

BOTOX is used in various therapeutic applications beyond cosmetics, such as treating migraines, overactive bladder, and other health conditions. This diversification of use cases has expanded its market reach[3].

Financial Performance

Revenue Growth

Global BOTOX Cosmetic net revenues saw an increase of 11.8% on a reported basis and 12.3% on an operational basis in 2023, reaching $718 million. This growth is part of a broader trend where the aesthetics portfolio of companies like AbbVie has shown significant revenue increases[2][5].

Segment Contribution

The cosmetic applications segment, particularly within clinics and med spas, leads the market share. This segment caters to a large volume of aesthetic procedures, contributing substantially to the overall revenue[4].

Challenges and Restraints

Safety Concerns and Side Effects

Despite its popularity, BOTOX faces challenges related to safety concerns and potential side effects. These issues can impact consumer confidence and market growth[4].

High Cost of Treatment

The high cost of BOTOX treatments is another significant barrier, especially in regions with limited healthcare reimbursement policies for cosmetic procedures[4].

Regulatory and Competitive Landscape

Stringent regulations and competition from biosimilars and other minimally invasive procedures also pose challenges to the market. Additionally, negative perception and social stigma can affect adoption rates[4].

Major Players

Companies like Allergan Aesthetics (now part of AbbVie), Galderma, Merz Pharma, and others are key players in the BOTOX market. These companies invest heavily in research and development, marketing, and promotional activities to drive market growth[4].

Marketing and Promotional Efforts

Marketing and promotional endeavors by major companies play a crucial role in boosting product awareness and adoption. Highlighting the convenience and advantages of BOTOX treatments has been instrumental in driving consumer interest and market expansion[3].

Future Outlook

The future outlook for the BOTOX Cosmetic market is promising. With continued technological advancements, growing demand for non-invasive procedures, and expanding therapeutic applications, the market is set for significant growth.

"The increasing demand for botulinum toxin in cosmetic and non-cosmetic applications and frequent product launches are expected to drive the market's growth over the forecast period."[3]

Key Takeaways

• The global BOTOX market is projected to reach USD 15.2 billion by 2030, growing at a CAGR of 11.50% from 2022 to 2030.
• North America dominates the market, followed by Europe and the Asia Pacific.
• Increasing demand for aesthetic procedures, technological advancements, and growing therapeutic applications are key drivers.
• Safety concerns, high treatment costs, and regulatory challenges are significant restraints.
• Major players like Allergan Aesthetics and Galderma drive market growth through R&D and marketing efforts.

FAQs

What is the current market size of the BOTOX Cosmetic market?

The global BOTOX market was valued at USD 6.4 billion in 2022 and is expected to grow significantly over the forecast period[1].

What are the primary drivers of the BOTOX Cosmetic market?

The primary drivers include increasing demand for aesthetic procedures, technological advancements, and growing therapeutic applications[1][3].

Which region dominates the BOTOX Cosmetic market?

North America dominates the global BOTOX market, holding a significant market share due to high awareness levels and advanced technological infrastructure[1].

What are the major challenges faced by the BOTOX Cosmetic market?

The market faces challenges such as safety concerns, high treatment costs, stringent regulations, and competition from biosimilars and other minimally invasive procedures[4].

Who are the major players in the BOTOX Cosmetic market?

Major players include Allergan Aesthetics, Galderma, Merz Pharma, and others who invest in R&D and marketing efforts to drive market growth[4].

Cited Sources:

1. The Brainy Insights - Botox Market Growth, Values, Analysis [2030][1]
2. AbbVie - Reports Full-Year and Fourth-Quarter 2023 Financial Results[2]
3. Mordor Intelligence - Botulinum Toxin Market Overview - Industry Analysis, Size ...[3]
4. Credence Research - Botox Market Size, Growth, Analysis & Forecast to 2032[4]
5. American Med Spa Association - AbbVie Reports Full-Year and Fourth-Quarter 2023 Financial Results[5]