CINRYZE Drug Profile
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Summary for Tradename: CINRYZE
| High Confidence Patents: | 0 |
| Applicants: | 1 |
| BLAs: | 1 |
| Recent Clinical Trials: | See clinical trials for CINRYZE |
Recent Clinical Trials for CINRYZE
Identify potential brand extensions & biosimilar entrants
| Sponsor | Phase |
|---|---|
| Netherlands Brain Foundation | Phase 2 |
| Leiden University Medical Center | Phase 2 |
| Takeda | Phase 2 |
Pharmacology for CINRYZE
| Mechanism of Action | Kallikrein Inhibitors |
| Physiological Effect | Decreased Vascular Permeability |
| Established Pharmacologic Class | Human C1 Esterase Inhibitor |
Note on Biologic Patents
Matching patents to biologic drugs is far more complicated than for small-molecule drugs.
DrugPatentWatch employs three methods to identify biologic patents:
- Brand-side disclosures in response to biosimilar applications
- General brand-side disclosures
- Patents from broad patent text search
These patents were identified from disclosures by the brand-side company, in response to a potential biosimilar seeking to launch. They have a high certainty of blocking biosimilar entry. The expiration dates listed are not estimates — they're expiration dates as indicated by the brand-side company.
These patents were identified from searching drug labels and other general disclosures from the brand-side company. This list may exclude some of the patents which block biosimilar launch, and some of these patents listed may not actually block biosimilar launch. The expiration dates listed for these patents are estimates, based on the grant date of the patent.
For completeness, these patents were identified by searching the patent literature for mentions of the branded or ingredient name of the drug. Some of these patents protect the original drug, whereas others may protect follow-on inventions or even inventions casually mentioning the drug. The expiration dates listed for these patents are estimates, based on the grant date of the patent.
1) High Certainty: US Patents for CINRYZE Derived from Brand-Side Litigation
No patents found based on brand-side litigation
2) High Certainty: US Patents for CINRYZE Derived from Company Disclosures
No patents found based on company disclosures
3) Low Certainty: US Patents for CINRYZE Derived from Patent Text Search
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Patent No. | Estimated Patent Expiration | Source |
|---|---|---|---|---|---|---|---|
| Takeda Pharmaceuticals U.s.a., Inc. | CINRYZE | c1 esterase inhibitor (human) | For Injection | 125267 | ⤷ Sign Up | 2036-04-04 | Patent claims search |
| Takeda Pharmaceuticals U.s.a., Inc. | CINRYZE | c1 esterase inhibitor (human) | For Injection | 125267 | ⤷ Sign Up | 2036-04-04 | Patent claims search |
| Takeda Pharmaceuticals U.s.a., Inc. | CINRYZE | c1 esterase inhibitor (human) | For Injection | 125267 | ⤷ Sign Up | 2040-09-30 | Patent claims search |
| Takeda Pharmaceuticals U.s.a., Inc. | CINRYZE | c1 esterase inhibitor (human) | For Injection | 125267 | ⤷ Sign Up | 2037-10-04 | Patent claims search |
| Takeda Pharmaceuticals U.s.a., Inc. | CINRYZE | c1 esterase inhibitor (human) | For Injection | 125267 | ⤷ Sign Up | 2031-06-10 | Patent claims search |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Patent No. | >Estimated Patent Expiration | >Source |
