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Last Updated: January 5, 2025

DYSPORT Drug Profile


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Summary for Tradename: DYSPORT
High Confidence Patents:0
Applicants:1
BLAs:1
Recent Clinical Trials: See clinical trials for DYSPORT
Recent Clinical Trials for DYSPORT

Identify potential brand extensions & biosimilar entrants

SponsorPhase
Universita di VeronaPhase 2
University of PennsylvaniaN/A
Clinical Testing of Beverly HillsPhase 1/Phase 2

See all DYSPORT clinical trials

Pharmacology for DYSPORT
Mechanism of ActionAcetylcholine Release Inhibitors
Physiological EffectNeuromuscular Blockade
Established Pharmacologic ClassAcetylcholine Release Inhibitor
Neuromuscular Blocker
Note on Biologic Patents

Matching patents to biologic drugs is far more complicated than for small-molecule drugs.

DrugPatentWatch employs three methods to identify biologic patents:

  1. Brand-side disclosures in response to biosimilar applications
  2. These patents were identified from disclosures by the brand-side company, in response to a potential biosimilar seeking to launch. They have a high certainty of blocking biosimilar entry. The expiration dates listed are not estimates — they're expiration dates as indicated by the brand-side company.

  3. General brand-side disclosures
  4. These patents were identified from searching drug labels and other general disclosures from the brand-side company. This list may exclude some of the patents which block biosimilar launch, and some of these patents listed may not actually block biosimilar launch. The expiration dates listed for these patents are estimates, based on the grant date of the patent.

  5. Patents from broad patent text search
  6. For completeness, these patents were identified by searching the patent literature for mentions of the branded or ingredient name of the drug. Some of these patents protect the original drug, whereas others may protect follow-on inventions or even inventions casually mentioning the drug. The expiration dates listed for these patents are estimates, based on the grant date of the patent.

1) High Certainty: US Patents for DYSPORT Derived from Brand-Side Litigation

No patents found based on brand-side litigation

2) High Certainty: US Patents for DYSPORT Derived from Company Disclosures

No patents found based on company disclosures

3) Low Certainty: US Patents for DYSPORT Derived from Patent Text Search

These patents were obtained by searching patent claims

DYSPORT Market Analysis and Financial Projection

Market Dynamics and Financial Trajectory for Dysport

Introduction

Dysport, a type A botulinum toxin, has been a significant player in the aesthetic and therapeutic markets since its FDA approval in 2009. Here, we delve into the market dynamics and financial trajectory of Dysport, highlighting its performance, growth drivers, and future outlook.

Market Dominance of Type A Botulinum Toxin

The type A botulinum toxin segment, which includes Dysport and Botox, has dominated the market due to their widespread commercial availability, clinical testing, and proven safety and efficacy. These products are favored for their long-term effectiveness and minimal side effects[1].

Aesthetic Applications

The aesthetic application segment is a key growth area for Dysport. Growing concerns over cosmetic features in both developed and developing countries have led to a significant rise in aesthetic procedures. This segment is expected to register a substantial CAGR of 12.4% during the forecast period, driven by increasing demand for non-surgical treatments[1].

Geographic Performance

North America has been a leading market for Dysport, with a revenue share of over 36.8% in 2022. This dominance is attributed to technological advancements in cosmetic treatments and the increasing number of specialists and service providers in the region. However, the Asia Pacific region is expected to register the highest CAGR of 14.4% over the forecast period, driven by a growing patient population, rising awareness of aesthetic procedures, and rapid technological advancements[1].

Financial Performance of Galderma

Galderma, the company behind Dysport, has shown robust financial performance in recent years. In 2023, Galderma achieved record net sales of over $4 billion, with a year-on-year growth of 8.5% on a constant currency basis. The Injectable Aesthetics category, which includes Dysport, saw a 6.5% year-on-year net sales growth, driven by double-digit growth in neuromodulators across key markets[3].

Core EBITDA and Margin Expansion

Galderma's Core EBITDA for 2023 was $942 million, representing a 23.1% Core EBITDA margin. This marked a significant expansion of 281 basis points on a constant currency basis compared to the previous year. The margin expansion was driven by gains from premiumization, structural cost savings, and operating expenses leverage[3].

Growth Drivers

Several factors contribute to the growth of Dysport:

  • Clinical Studies and Innovation: Continuous investments in clinical studies evaluating duration and patient satisfaction have been crucial. For instance, Dysport has outgrown the market for the past three years, with plans for further growth through additional clinical studies[4].
  • Market Share Gains: Dysport has achieved market share gains across all key markets, particularly in the neuromodulator segment[3].
  • Consumer Loyalty Programs: Programs like the ASPIRE Galderma Rewards program have helped in retaining customers and driving repeat business[4].

Partnership and Collaborations

Galderma's partnership with Ipsen, the manufacturer of Dysport, has been instrumental in its success. Ipsen's strong financial performance, including a 14.4% increase in total sales in 2022, has been partly driven by the growth in sales of Dysport to Galderma[5].

Future Outlook

Galderma expects to deliver 7-10% net sales growth on a constant currency basis in 2024, with the Core EBITDA margin expected to remain in line with 2023 levels. Despite increased investments in nemolizumab, Galderma anticipates continued expansion in underlying profitability, executing its integrated dermatology strategy[3].

Consumer Satisfaction

Dysport has received high satisfaction ratings from consumers. For example, it achieved a 97% “Worth It” rating on RealSelf in 2019, making it one of the top-rated nonsurgical treatments[4].

Market Impact

The aesthetic market has grown exponentially since Dysport's approval, and Galderma remains committed to driving this growth through innovative products and services. The company's focus on providing value to customers and patients is evident in its ongoing investments in clinical trials, product promotions, and collaboration partnerships[4].

Key Statistics

  • Revenue Growth: Galderma's net sales grew by 8.5% in 2023 to over $4 billion[3].
  • CAGR: The aesthetic application segment is expected to register a CAGR of 12.4%[1].
  • Market Share: Dysport has gained significant market share in neuromodulators across key markets[3].
  • Consumer Satisfaction: Dysport received a 97% “Worth It” rating on RealSelf in 2019[4].

Conclusion

Dysport's market dynamics are characterized by strong growth in the aesthetic segment, driven by increasing demand for non-surgical treatments and technological advancements. Galderma's financial trajectory reflects this growth, with significant revenue increases and margin expansions. As the company continues to invest in innovation and clinical studies, Dysport is poised for continued success in the market.

Key Takeaways

  • Dysport dominates the type A botulinum toxin market due to its safety, efficacy, and widespread availability.
  • The aesthetic application segment is a key growth driver, expected to register a CAGR of 12.4%.
  • North America leads in revenue, but the Asia Pacific region is expected to grow at the highest CAGR.
  • Galderma's financial performance is robust, with record net sales and expanding Core EBITDA margins.
  • Continuous investments in clinical studies and consumer loyalty programs drive growth.
  • Future outlook is positive, with expected net sales growth and maintained profitability.

FAQs

Q: What is the primary segment driving the growth of Dysport? A: The aesthetic application segment is the primary driver, with a projected CAGR of 12.4% during the forecast period.

Q: Which region is expected to have the highest CAGR for Dysport? A: The Asia Pacific region is expected to register the highest CAGR of 14.4% over the forecast period.

Q: How has Galderma's financial performance been in recent years? A: Galderma achieved record net sales of over $4 billion in 2023, with a year-on-year growth of 8.5% on a constant currency basis.

Q: What factors contribute to the growth of Dysport? A: Factors include continuous investments in clinical studies, market share gains, and consumer loyalty programs.

Q: What is the future outlook for Dysport's sales and profitability? A: Galderma expects 7-10% net sales growth on a constant currency basis in 2024, with maintained Core EBITDA margins.

Sources

  1. GlobeNewswire - Botulinum Toxin Market Size, Share & Trends Analysis Report 2023
  2. BioSpace - Ipsen Presents Strong Full-Year 2021 Results and Enters Into Exclusive Negotiations to Divest Its Consumer Healthcare Business
  3. Galderma - Galderma announces record 2023 net sales of over 4 B USD and significant core EBITDA margin
  4. Galderma - A Decade of Dysport®: Galderma Celebrates 10 Years Since FDA Approval in the US
  5. GlobeNewswire - Ipsen presents strong full-year 2022 results and guidance for 2023

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