Market Dynamics and Financial Trajectory for 1,1,1,2,2,3,3,4,4-Nonafluorobutane as a Pharmaceutical Excipient
Introduction
1,1,1,2,2,3,3,4,4-Nonafluorobutane, also known as 1H-Nonafluorobutane, is a chemical compound with the molecular formula C₄HF₉. While it is not traditionally considered a pharmaceutical excipient, understanding its properties and market dynamics can provide insights into its potential applications and financial trajectory in related industries.
Properties and Applications
Chemical Properties
1H-Nonafluorobutane has a molecular weight of 220.04 g/mol and a boiling point of 14 ℃. It is highly stable and resistant to chemical reactions, which makes it suitable for various industrial applications[1].
Potential in Pharmaceutical Industry
Although 1H-Nonafluorobutane is not commonly used as a pharmaceutical excipient, its stability and chemical inertness could make it a candidate for specific roles, such as in the formulation of certain drugs or as a solvent in pharmaceutical processes.
Market Dynamics
Pharmaceutical Excipients Market Overview
The global pharmaceutical excipients market is experiencing significant growth, projected to increase from $9,728.83 billion in 2023 to $10,378.8 billion in 2024, with a compound annual growth rate (CAGR) of 6.7%. This growth is driven by factors such as robust economic development in emerging markets, an increase in the market for generic drugs, and the establishment of advanced healthcare infrastructure[3].
Emerging Trends
Key trends in the pharmaceutical excipients market include a focus on sustainable packaging, mergers and acquisitions to strengthen market positions, reducing greenhouse gas emissions, and the use of artificial intelligence to enhance supply chain transparency and efficiency. These trends could influence the adoption of new and innovative excipients, including those with unique chemical properties like 1H-Nonafluorobutane[3].
Financial Trajectory
Current Market Size and Growth
While 1H-Nonafluorobutane is not a significant player in the pharmaceutical excipients market currently, its potential applications could lead to niche market opportunities. The overall pharmaceutical excipients market is expected to grow to $13,399.77 billion by 2028, driven by government initiatives, innovative drug development, increasing healthcare expenditure, and a rising elderly population[3].
Pricing and Availability
The pricing of 1H-Nonafluorobutane is relatively high, with 10g costing around $175 and 25g costing around $350. Bulk quantities are available upon request. This pricing structure suggests that the compound is not yet widely used in large-scale applications but could be viable for specialized uses[1].
Regulatory Considerations
Safety and Regulatory Status
1H-Nonafluorobutane is not listed on the TSCA inventory, and it has specific DOT/IATA/IMDG classifications. Its flash point is none, indicating it is not flammable. These regulatory aspects are crucial for any potential use in the pharmaceutical industry, where safety and compliance are paramount[1].
Environmental and Health Implications
Comparison with Other PFAS
While 1H-Nonafluorobutane is not a per- and polyfluoroalkyl substance (PFAS) in the traditional sense, its fluorinated structure raises concerns similar to those associated with PFAS. Studies on PFAS have shown adverse health and environmental effects, which could influence the regulatory and public perception of compounds like 1H-Nonafluorobutane[2].
Potential Applications in Pharmaceuticals
Solvents and Formulation Aids
Given its chemical stability and inertness, 1H-Nonafluorobutane could be explored as a solvent or formulation aid in pharmaceutical manufacturing. Its low boiling point makes it a potential candidate for processes requiring quick evaporation or low-temperature reactions.
Specialized Excipients
Innovative pharmaceutical formulations might benefit from the unique properties of 1H-Nonafluorobutane. For instance, its stability could make it useful in the development of drugs requiring high chemical inertness.
Challenges and Opportunities
Research and Development
Further research is needed to fully explore the potential of 1H-Nonafluorobutane in pharmaceutical applications. This includes studying its compatibility with various active pharmaceutical ingredients (APIs) and its impact on drug stability and efficacy.
Market Penetration
Entering the pharmaceutical excipients market would require significant investment in marketing, regulatory compliance, and establishing supply chains. However, the growing demand for innovative excipients presents an opportunity for niche players.
Key Takeaways
- Market Growth: The pharmaceutical excipients market is growing rapidly, driven by emerging markets, generic drugs, and advanced healthcare infrastructure.
- Potential Applications: 1H-Nonafluorobutane's stability and inertness make it a potential candidate for specialized roles in pharmaceutical manufacturing.
- Regulatory Considerations: Compliance with safety and regulatory standards is crucial for any new excipient.
- Environmental and Health Implications: The compound's fluorinated structure raises concerns similar to those associated with PFAS.
- Research and Development: Further studies are necessary to fully explore its potential in pharmaceutical applications.
FAQs
Q: What is the molecular formula of 1H-Nonafluorobutane?
A: The molecular formula of 1H-Nonafluorobutane is C₄HF₉[1].
Q: What are the potential applications of 1H-Nonafluorobutane in the pharmaceutical industry?
A: It could be used as a solvent or formulation aid due to its chemical stability and low boiling point[1].
Q: How does the pricing of 1H-Nonafluorobutane compare to other chemicals?
A: The pricing is relatively high, with 10g costing around $175 and 25g costing around $350, indicating it is not yet widely used in large-scale applications[1].
Q: What are the regulatory considerations for using 1H-Nonafluorobutane in pharmaceuticals?
A: It is not listed on the TSCA inventory and has specific DOT/IATA/IMDG classifications, which are crucial for compliance[1].
Q: How does 1H-Nonafluorobutane compare to other PFAS in terms of environmental and health implications?
A: While not a traditional PFAS, its fluorinated structure raises similar concerns regarding adverse health and environmental effects[2].
Sources
- SynQuest Labs: 1H-Nonafluorobutane.
- OECD/UNEP Global PFC Group: Fact Cards of Major Groups of Per- and Polyfluoroalkyl Substances (PFASs).
- Research and Markets: Pharmaceutical Excipients Global Market Report 2024.
- BenchChem: 1-Chlorononafluorobutane.
- DTIC: Predicting Toxicity and Degradability of Quadricyclane and Its Analogs.
