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Last Updated: April 14, 2025

Drugs Containing Excipient (Inactive Ingredient) DIPROPYLENE GLYCOL


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Branded drugs containing DIPROPYLENE GLYCOL excipient, and estimated key patent expiration / generic entry dates

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Dipropylene Glycol (DPG) in the Pharmaceutical and Chemical Industries: Market Dynamics and Financial Trajectory

Introduction

Dipropylene glycol (DPG) is a versatile chemical compound that finds extensive use in various industries, including pharmaceuticals, cosmetics, and chemicals. Its unique properties, such as low toxicity, high solubility, and minimal odor, make it an essential component in several applications. Here, we delve into the market dynamics and financial trajectory of DPG, particularly focusing on its role as a pharmaceutical excipient.

Market Segmentation

The DPG market is segmented based on grade and application.

By Grade

  • Industrial Grade: This segment accounts for more than 40% of the DPG market. It is widely used in the production of plastics, polyurethane resins, and other chemical applications[2].
  • Cosmetics Grade: This segment is growing due to the increasing demand for body care and personal care products. Cosmetics grade DPG is used in perfumes, body lotions, and other cosmetic formulations[2].

By Application

  • Perfumes and Fragrances: DPG is used as a carrier for fragrances and in deodorant applications due to its low odor and high solubility[3].
  • Plasticizers: It is used as a plasticizer in the production of plastics and polyurethane resins[2].
  • Chemical Intermediates: DPG serves as a solvent, coupling agent, and chemical intermediate in various chemical processes[3].
  • Pharmaceutical Excipients: Although not as widely discussed, DPG can be used in pharmaceutical formulations due to its solubilizing properties and low toxicity.

Market Drivers

Several factors drive the demand for DPG:

Increasing Demand from Personal Care and Cosmetics

The growing personal care and cosmetics industries, particularly in Asia-Pacific, are significant drivers. The use of DPG in perfume manufacturing, body lotions, and other cosmetic products is on the rise due to its low toxicity and high solubility[1][3].

Chemical and Polymer Industries

DPG's applications as a plasticizer, polymerization initiator, and additive in the chemical and polymer industries are also driving market growth. The demand for polyurethane resins, unsaturated polyester resins (UPR), and alkyd resins contributes to this growth[1].

Emerging Economies

The increasing demand from emerging economies, where there is a growing need for chemicals and cosmetics, is another key driver. Countries like China and India are driving the demand for DPG in various applications[2][3].

Market Restraints

Despite the positive drivers, there are several restraints to consider:

Side Effects and Irritation

DPG can act as a skin and eye irritant, which may limit its use in certain applications. This side effect is a significant restraint, especially in industries where user safety is paramount[1].

Availability of Substitutes

The presence of substitutes like 2-Methyl-1,3-propanediol (MPO) can hinder the growth of the DPG market. These alternatives may offer similar properties at a lower cost or with fewer side effects[1][3].

Regional Insights

The global DPG market is geographically segmented into several regions:

Asia-Pacific

This region dominates the DPG market due to high demand from China and India for plasticizers and polyurethane resins. The growing textile industry in this region also increases the demand for textile lubricants, which use DPG[1][2][3].

North America and Europe

These regions are expected to grow significantly due to the increasing use of glycols in printing inks, perfumes, body lotions, and other products. The personal care and fragrance industries in these regions are also driving the demand for DPG[1][2].

Latin America and Middle East & Africa

These regions are expected to show slower growth compared to other regions, primarily due to less developed industrial sectors and lower demand for DPG-based products[1][2].

Financial Trajectory

The financial outlook for the DPG market is promising:

Market Size and Growth

The global DPG market is expected to reach USD 5.71 billion by 2030, growing at a CAGR of 2.4% during the forecast period. In 2021, the market accounted for around 160 kilo tons and is projected to register a CAGR of over 4% until 2027[2][3].

Price Trends

The price trend for DPG has been fluctuating due to various factors such as raw material costs, economic conditions, and logistical challenges. In 2023, prices declined in North America due to economic concerns and logistical obstacles, while in Asia, prices fluctuated due to changes in demand and supply dynamics[5].

Pharmaceutical Excipients Market Context

While DPG is not as commonly discussed as a pharmaceutical excipient, its properties make it a potential candidate for use in pharmaceutical formulations.

Solubilizing Properties

DPG's high solubility makes it useful for solubilizing other substances, such as Castor Oil, which is used in various pharmaceutical and cosmetic products[2].

Low Toxicity

The low toxicity of DPG is a critical factor in pharmaceutical applications, where safety is paramount. However, its potential as a skin and eye irritant must be carefully managed[1].

Key Players

Several major companies operate in the DPG market:

  • BASF
  • LyondellBasell
  • Huntsman
  • Shell
  • INEOS
  • Dow
  • Sumitomo
  • Manali Petrochemicals[1][2][3].

Future Outlook

The future of the DPG market looks promising, driven by increasing demand from various industries. However, the market must navigate challenges such as the availability of substitutes and the potential side effects of DPG.

Bio-Based DPG

The rising trend for bio-based DPG is expected to create lucrative growth opportunities. This shift towards more sustainable and environmentally friendly products could further boost the market[3].

Emerging Applications

New applications in the pharmaceutical and cosmetic industries, particularly in emerging economies, will continue to drive the demand for DPG.

Key Takeaways

  • Market Growth: The DPG market is expected to grow at a CAGR of 2.4% to reach USD 5.71 billion by 2030.
  • Regional Dominance: Asia-Pacific dominates the market due to high demand from China and India.
  • Applications: DPG is used in perfumes, plasticizers, chemical intermediates, and potentially as a pharmaceutical excipient.
  • Challenges: Side effects, availability of substitutes, and fluctuating price trends are key restraints.
  • Future Outlook: Bio-based DPG and emerging applications in pharmaceuticals and cosmetics are expected to drive future growth.

FAQs

What are the primary applications of Dipropylene Glycol (DPG)?

DPG is primarily used in perfumes, plasticizers, chemical intermediates, and in the production of polyurethane resins and unsaturated polyester resins (UPR)[1][2][3].

Which region dominates the DPG market?

The Asia-Pacific region dominates the DPG market due to high demand from countries like China and India[1][2][3].

What are the key drivers of the DPG market?

The key drivers include increasing demand from personal care and cosmetics industries, applications in chemical and polymer industries, and growing demand from emerging economies[1][2][3].

What are the potential restraints on the DPG market?

The availability of substitutes like 2-Methyl-1,3-propanediol (MPO) and the potential side effects of DPG, such as skin and eye irritation, are significant restraints[1][3].

What is the expected market size of DPG by 2030?

The global DPG market is expected to reach USD 5.71 billion by 2030, growing at a CAGR of 2.4% during the forecast period[2].

Who are the major players in the DPG market?

Major players include BASF, LyondellBasell, Huntsman, Shell, INEOS, Dow, Sumitomo, and Manali Petrochemicals[1][2][3].

Sources

  1. Fortune Business Insights - Dipropylene Glycol (DPG) Market Size, Industry Share, Forecast 2032
  2. Maximize Market Research - Dipropylene Glycol Market - Industry Analysis and Forecast 2030
  3. Mordor Intelligence - Dipropylene Glycol Market - Manufacturers, Trends & Size
  4. MarketsandMarkets - Pharmaceutical Excipients Market Growth, Drivers, and Opportunities
  5. Procurement Resource - Dipropylene Glycol Price Trend and Forecast

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