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Last Updated: March 13, 2025

Drugs Containing Excipient (Inactive Ingredient) PHOSPHORIC ACID


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Branded drugs containing PHOSPHORIC ACID excipient, and estimated key patent expiration / generic entry dates

CompanyTradenameIngredientNDCExcipientPotential Generic Entry
Merck Sharp & Dohme Corp ELOCON mometasone furoate 0085-0370 PHOSPHORIC ACID
Merck Sharp & Dohme Corp ELOCON mometasone furoate 0085-0854 PHOSPHORIC ACID
Novartis Pharmaceuticals Corporation LEQVIO inclisiran 0078-1000 PHOSPHORIC ACID 2034-08-18
>Company>Tradename>Ingredient>NDC>Excipient>Potential Generic Entry
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Market Dynamics and Financial Trajectory for Phosphoric Acid as a Pharmaceutical Excipient

Introduction to Phosphoric Acid in Pharmaceuticals

Phosphoric acid, a versatile and essential chemical, plays a critical role in various industries, including the pharmaceutical sector. Its applications in pharmaceutical formulations, dental care, and food processing make it a highly sought-after commodity. Here, we delve into the market dynamics and financial trajectory of phosphoric acid, particularly focusing on its role as a pharmaceutical excipient.

Growing Role in Pharmaceutical Formulations

Phosphoric acid is widely used in the pharmaceutical industry as an active pharmaceutical ingredient (API), excipient, acidulant, and buffering agent. Its versatility enhances therapeutic properties, improves drug stability, solubility, and bioavailability[2][4].

Use in Drug Synthesis

Phosphoric acid is an intermediate in the production of various pharmaceuticals, including anti-nausea drugs. Its ability to act as a buffering agent helps in maintaining the pH levels necessary for the stability of many medications[3].

Dental Applications

In dentistry, phosphoric acid is used for etching teeth and in teeth whitening products. Its application in mouthwashes and other dental care products further underscores its importance in the healthcare sector[3].

Market Drivers

Several factors drive the demand for phosphoric acid in the pharmaceutical sector:

Increasing Healthcare Spending

The global focus on healthcare and medical advancements is a significant driver. Rising spending on pharmaceutical products, particularly in the United States, where healthcare spending is among the highest, fuels the demand for purified phosphoric acid. In 2019, U.S. prescription drug expenditures totaled $370 billion, indicating a substantial market for pharmaceuticals and, by extension, for phosphoric acid[4].

Growing Demand from Emerging Markets

The Asia-Pacific region, led by countries like China, India, and Indonesia, is experiencing rapid growth in the healthcare sector. This region's increasing utilization of phosphoric acid in pharmaceutical and food applications is expected to drive market growth[1][5].

Expanding Production Capacities

Manufacturers are expanding their production capacities to meet the growing demand for high-quality, pharmaceutical-grade phosphoric acid. This expansion is driven by the higher profit margins associated with pharmaceutical-grade products[2].

Financial Trajectory

Current Market Size and Growth Projections

The global purified phosphoric acid market was valued at $8,702.8 million in 2023 and is projected to reach $13,782.4 million by 2033, growing at a Compound Annual Growth Rate (CAGR) of 4.7% during this period[2][4].

Regional Market Dynamics

  • Asia-Pacific: This region is expected to dominate the phosphoric acid market, driven by its increasing use in the healthcare and food sectors. China is a key player, with significant demand for phosphoric acid in healthcare applications[1][5].
  • Europe: Germany leads the European market, with the wet process segment being predominant due to its production advantages[1].
  • United States: The U.S. market is driven by high healthcare spending and the rapid expansion of the pharmaceutical sector, making it a significant market for purified phosphoric acid[4].

Segment-wise Market Share

The pharmaceutical segment holds a substantial share of the global purified phosphoric acid market, with over 28% market share. This is due to the high price and demand for pharmaceutical-grade phosphoric acid[4].

Key Market Shaping Factors

Quality and Purification

High-quality purified phosphoric acid is in high demand due to its rigorous purification processes that eliminate impurities and contaminants. This premium-grade form is essential for pharmaceutical applications where purity is critical[4].

Diverse Applications

Phosphoric acid's versatility extends beyond pharmaceuticals to include agriculture, food & beverages, electronics, and chemicals. Its use in fertilizer production, pH regulation, and electronic component manufacturing further diversifies its market[4].

Regulatory and Government Initiatives

Government initiatives promoting sustainable agriculture practices and the use of fertilizers are expected to support market growth, particularly in regions like the Asia-Pacific[5].

Competitive Landscape

Market Leaders and Expansion Strategies

Prominent manufacturers are focusing on expanding their production capacities and updating their product portfolios to include more pharmaceutical-grade products. This strategy is driven by the higher profit margins associated with these products[2].

Regional Competitiveness

The presence of key manufacturers in regions like the Asia-Pacific and North America influences the competitive landscape. Companies are competing to meet the specific requirements of diverse sectors, including pharmaceuticals and food & beverages[5].

Challenges and Opportunities

Regulatory Compliance

Ensuring compliance with stringent regulatory standards, particularly in the pharmaceutical sector, is a challenge. However, this also presents an opportunity for manufacturers to differentiate themselves by offering high-quality, compliant products[4].

Sustainability and Environmental Concerns

The production of phosphoric acid, especially through the wet process, can have environmental implications. Manufacturers must balance production needs with sustainability and environmental responsibility, which can be both a challenge and an opportunity for innovation[1].

Key Takeaways

  • Phosphoric acid is a critical component in pharmaceutical formulations, dental care, and other healthcare products.
  • The global purified phosphoric acid market is projected to grow at a CAGR of 4.7% from 2023 to 2033.
  • The Asia-Pacific region, particularly China, and the United States are key markets driven by healthcare spending and industrial growth.
  • High-quality, pharmaceutical-grade phosphoric acid is in high demand due to its purity and versatility.
  • Manufacturers are expanding production capacities to meet growing demand, especially in the pharmaceutical sector.

FAQs

What are the primary applications of phosphoric acid in the pharmaceutical industry?

Phosphoric acid is used as an API, excipient, acidulant, and buffering agent in pharmaceutical formulations. It is also used in dental care products like teeth etching solutions and mouthwashes.

How is the global purified phosphoric acid market expected to grow?

The global purified phosphoric acid market is expected to grow at a CAGR of 4.7% from 2023 to 2033, reaching a market size of $13,782.4 million by 2033.

Which regions are leading the demand for phosphoric acid?

The Asia-Pacific region, led by China, and the United States are the leading markets for phosphoric acid, driven by their significant healthcare spending and industrial growth.

What drives the demand for pharmaceutical-grade phosphoric acid?

The demand for pharmaceutical-grade phosphoric acid is driven by its high price and the growing need for high-quality, pure products in pharmaceutical formulations.

How do government initiatives impact the phosphoric acid market?

Government initiatives promoting sustainable agriculture practices and the use of fertilizers support market growth, particularly in regions like the Asia-Pacific.

Sources

  1. Global Phosphoric Acid Market – Industry Trends and Forecast to 2031. Databridge Market Research.
  2. Pharmaceutical and Food Sectors Present Massive Demand; Purified Phosphoric Acid Sales to Exceed US$ 13,782.4 Million by 2033. GlobeNewswire.
  3. Phosphoric Acid: Common Application, Uses & Properties. PCIPL India.
  4. Purified Phosphoric Acid Market Size & Demand to 2033. Future Market Insights.
  5. Phosphoric Acid Market: High Usage of Phosphoric Acid in Medical. Maximize Market Research.

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