DESOXIMETASONE - Generic Drug Details

What are the generic sources for desoximetasone and what is the scope of freedom to operate?

Desoximetasone is the generic ingredient in three branded drugs marketed by Actavis Mid Atlantic, Cosette, Fougera Pharms, Lupin, Padagis Israel, Rising, Sciegen Pharms Inc, Zydus Lifesciences, Taro, Epic Pharma Llc, Padagis Us, Altana, Glenmark Pharms Ltd, Novel Labs Inc, Pai Holdings Pharm, and The J Molner, and is included in forty NDAs. There are two patents protecting this compound and one Paragraph IV challenge. Additional information is available in the individual branded drug profile pages.

Desoximetasone has four patent family members in four countries.

There are seven drug master file entries for desoximetasone. Twelve suppliers are listed for this compound.

Summary for DESOXIMETASONE

International Patents:	4
US Patents:	2
Tradenames:	3
Applicants:	16
NDAs:	40
Drug Master File Entries:	7
Finished Product Suppliers / Packagers:	12
Raw Ingredient (Bulk) Api Vendors:	65
Clinical Trials:	10
Patent Applications:	5,969
Drug Prices:	Drug price trends for DESOXIMETASONE
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for DESOXIMETASONE
What excipients (inactive ingredients) are in DESOXIMETASONE?	DESOXIMETASONE excipients list
DailyMed Link:	DESOXIMETASONE at DailyMed

See drug prices for DESOXIMETASONE

See drug sales revenues for DESOXIMETASONE

Recent Clinical Trials for DESOXIMETASONE

Identify potential brand extensions & 505(b)(2) entrants

Sponsor	Phase
Wake Forest University Health Sciences	Phase 4
Psoriasis Treatment Center of Central New Jersey	Phase 4
Siriraj Hospital	Phase 3

See all DESOXIMETASONE clinical trials

Pharmacology for DESOXIMETASONE

Drug Class	Corticosteroid
Mechanism of Action	Corticosteroid Hormone Receptor Agonists

Medical Subject Heading (MeSH) Categories for DESOXIMETASONE

Anti-Inflammatory Agents

Glucocorticoids

Anatomical Therapeutic Chemical (ATC) Classes for DESOXIMETASONE

D07AC	Corticosteroids, potent (group III)
D07A	CORTICOSTEROIDS, PLAIN
D07	CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D	Dermatologicals

D07XC	Corticosteroids, potent, other combinations
D07X	CORTICOSTEROIDS, OTHER COMBINATIONS
D07	CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D	Dermatologicals

Paragraph IV (Patent) Challenges for DESOXIMETASONE

Tradename	Dosage	Ingredient	Strength	NDA	ANDAs Submitted	Submissiondate
TOPICORT	Topical Spray	desoximetasone	0.25%	204141	1	2013-12-18

US Patents and Regulatory Information for DESOXIMETASONE

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Exclusivity Expiration
Taro	TOPICORT LP	desoximetasone	CREAM;TOPICAL	018309-001	Approved Prior to Jan 1, 1982		DISCN	Yes	No
Taro	TOPICORT	desoximetasone	CREAM;TOPICAL	017856-001	Approved Prior to Jan 1, 1982		DISCN	Yes	No
Lupin	DESOXIMETASONE	desoximetasone	CREAM;TOPICAL	208163-001	Jan 10, 2017	AB	RX	No	No

Expired US Patents for DESOXIMETASONE

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	Patent No.	Patent Expiration
Taro	TOPICORT	desoximetasone	SPRAY;TOPICAL	204141-001	Apr 11, 2013	5,990,100

International Patents for DESOXIMETASONE

Country	Patent Number	Title	Estimated Expiration
Israel	187666	הרכב נוזלי ויציב של דסוקסימטאסון ואיזופרופיל מיריסטט עם רמת זיהומים מחומצנים פחותה במהלך איחסון ארוך טווח (Stable liquid formulation comprising desoximetasone and isopropyl myristate with reduced oxidized impurity during long-term storage)
Canada	2609579	PREPARATION LIQUIDE STABLE COMPRENANT DE LA DESOXYMETASONE ET DU MYRISTATE ISOPROPYLIQUE A TENEUR REDUITE EN IMPURETES OXYDEES EN CAS DE STOCKAGE DE LONGUE DUREE (STABLE LIQUID DESOXIMETASONE COMPOSITIONS WITH REDUCED OXIDIZED IMPURITY)
European Patent Office	1888026	PREPARATION LIQUIDE STABLE COMPRENANT DE LA DESOXYMETASONE ET DU MYRISTATE ISOPROPYLIQUE A TENEUR REDUITE EN IMPURETES OXYDEES EN CAS DE STOCKAGE DE LONGUE DUREE (A STABLE LIQUID FORMULATION COMPRISING DESOXIMETASONE AND ISOPROPYL MYRISTATE WITH REDUCED OXIDIZED IMPURITY DURING LONG-TERM STORAGE)

DESOXIMETASONE Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Desoximetasone

Introduction to Desoximetasone

Desoximetasone is a potent topical corticosteroid used to treat various skin conditions, including eczema, psoriasis, and dermatitis. It is known for its anti-inflammatory properties and is applied directly to the skin to reduce inflammation and irritation.

Market Overview

The global market for topical corticosteroids, which includes desoximetasone, has been experiencing significant growth driven by several key factors.

Rising Prevalence of Dermatological Conditions

The increasing prevalence of skin disorders such as eczema, psoriasis, and dermatitis is a major driver of the market. As the global population grapples with these conditions, the demand for effective treatments like desoximetasone continues to rise[5].

Growing Geriatric Population

The geriatric population is more prone to skin-related issues, which has further fueled the demand for topical corticosteroids. This demographic shift is expected to continue driving market growth in the coming years[5].

Technological Advancements

Advancements in drug formulations have led to the development of more effective and safer topical corticosteroids. These innovations enhance therapeutic outcomes and patient compliance, contributing to the market's expansion[5].

Market Size and Growth Projections

The global topical corticosteroids market, which includes desoximetasone, was valued at USD 4,270.71 million in 2023 and is expected to grow to USD 6,102.07 million by 2030, at a Compounded Annual Growth Rate (CAGR) of 5.2%[5].

Key Manufacturers and Market Share

The desoximetasone market is dominated by several key manufacturers. A detailed analysis of these manufacturers includes their product specifications, production capacity, market share, and financial performance.

• Global Key Manufacturers: Companies such as Perrigo, among others, play a significant role in the production and distribution of desoximetasone. These companies have a substantial market share and are involved in continuous research and development to improve product efficacy and safety[2][5].

Market Dynamics

Upstream Raw Materials and Downstream Clients

The production of desoximetasone involves the procurement of specific raw materials. The availability and cost of these raw materials can significantly impact the production process and overall market dynamics. Downstream clients, including hospitals, pharmacies, and retail stores, also influence the market by driving demand and affecting distribution channels[1].

Current Market Trends

The market for desoximetasone is influenced by several trends, including the increasing preference for non-invasive treatment methods and the growing demand for localized treatment options. Technological innovations in drug delivery systems are also driving the market forward[3].

Regulatory Environment

The topical corticosteroids market, including desoximetasone, is subject to strict regulatory policies. These regulations can impact the approval and distribution of new products, affecting the overall market growth. Companies must comply with these regulations to ensure the safety and efficacy of their products[5].

Financial Trajectory

Historical Market Performance

From 2009 to 2014, the global and Chinese desoximetasone market experienced significant growth, driven by increasing demand for topical corticosteroids. The market was valued based on key economic parameters such as production value, market share, and capacity of major manufacturers[1].

Future Market Projections

The market for desoximetasone is expected to continue growing, driven by the factors mentioned above. By 2030, the global topical corticosteroids market is projected to reach USD 6,102.07 million, indicating a positive financial trajectory for desoximetasone and other topical corticosteroids[5].

Export and Import Dynamics

Desoximetasone is exported and imported globally, with key countries such as India, the United States, and Italy playing significant roles in the trade.

• Export Market Share: India accounts for the maximum share of desoximetasone exports, followed by the United States and Italy. This data is crucial for exporters and importers looking to expand their global trade and improve supply chain efficiency[4].

Challenges and Opportunities

Side Effects and Regulatory Concerns

Despite the growth potential, the market faces challenges such as concerns over the side effects of prolonged use of corticosteroids, including skin thinning and hormonal imbalances. Strict regulatory policies and high treatment costs are additional barriers to market growth[5].

Emerging Markets and Technological Advancements

Emerging markets, particularly in Asia and Latin America, offer significant opportunities for growth due to increasing disposable incomes and growing awareness about dermatological treatments. The rise of online pharmacies and advancements in telemedicine are also making these treatments more accessible[5].

Proposals for New Projects

For companies considering new projects in the desoximetasone industry, it is crucial to evaluate the feasibility based on market dynamics, regulatory environment, and technological advancements. Proposals should include detailed market analysis, production capacity planning, and strategies for compliance with regulatory requirements[1].

Conclusion

The market for desoximetasone is poised for continued growth, driven by the increasing prevalence of dermatological conditions, technological advancements, and expanding product availability. However, the market also faces challenges related to side effects and regulatory concerns. Understanding these dynamics is essential for stakeholders to make informed decisions and capitalize on emerging opportunities.

Key Takeaways

• The global topical corticosteroids market, including desoximetasone, is expected to grow at a CAGR of 5.2% from 2023 to 2030.
• The market is driven by the rising prevalence of dermatological conditions and technological advancements in drug formulations.
• Key manufacturers play a significant role in the production and distribution of desoximetasone.
• The market faces challenges such as side effects of prolonged use and strict regulatory policies.
• Emerging markets and advancements in telemedicine offer significant opportunities for growth.

FAQs

Q: What is desoximetasone used for?

Desoximetasone is a topical corticosteroid used to treat various skin conditions, including eczema, psoriasis, and dermatitis.

Q: What drives the demand for desoximetasone?

The demand for desoximetasone is driven by the increasing prevalence of dermatological conditions, technological advancements in drug formulations, and the growing geriatric population.

Q: Which countries are major exporters of desoximetasone?

India, the United States, and Italy are among the major exporters of desoximetasone.

Q: What are the challenges faced by the desoximetasone market?

The market faces challenges such as concerns over side effects of prolonged use, strict regulatory policies, and high treatment costs.

Q: What are the growth projections for the desoximetasone market?

The global topical corticosteroids market, including desoximetasone, is expected to grow to USD 6,102.07 million by 2030 at a CAGR of 5.2%.

Sources

1. Research and Markets: "Global and Chinese Desoximetasone Industry, 2009-2019" report.
2. Perrigo Company plc: Annual Report 2021.
3. Verified Market Research: "Topical Drug Delivery Market" report.
4. Volza: "Desoximetasone Exports from World".
5. Reanin: "Global Topical Corticosteroids Market" report.