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Last Updated: December 22, 2024

LEVOBETAXOLOL HYDROCHLORIDE - Generic Drug Details


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What are the generic sources for levobetaxolol hydrochloride and what is the scope of freedom to operate?

Levobetaxolol hydrochloride is the generic ingredient in one branded drug marketed by Alcon Pharms Ltd and is included in one NDA. Additional information is available in the individual branded drug profile pages.

There is one drug master file entry for levobetaxolol hydrochloride.

Summary for LEVOBETAXOLOL HYDROCHLORIDE
Recent Clinical Trials for LEVOBETAXOLOL HYDROCHLORIDE

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
Lee's Pharmaceutical LimitedPhase 3
Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd.Phase 3

See all LEVOBETAXOLOL HYDROCHLORIDE clinical trials

US Patents and Regulatory Information for LEVOBETAXOLOL HYDROCHLORIDE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Alcon Pharms Ltd BETAXON levobetaxolol hydrochloride SUSPENSION/DROPS;OPHTHALMIC 021114-001 Feb 23, 2000 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Expired US Patents for LEVOBETAXOLOL HYDROCHLORIDE

Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration
Alcon Pharms Ltd BETAXON levobetaxolol hydrochloride SUSPENSION/DROPS;OPHTHALMIC 021114-001 Feb 23, 2000 4,911,920*PED ⤷  Subscribe
Alcon Pharms Ltd BETAXON levobetaxolol hydrochloride SUSPENSION/DROPS;OPHTHALMIC 021114-001 Feb 23, 2000 5,540,918*PED ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >Patent No. >Patent Expiration

LEVOBETAXOLOL HYDROCHLORIDE Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Levobetaxolol Hydrochloride

Introduction

Levobetaxolol hydrochloride, a beta-blocker used primarily to treat conditions such as open-angle glaucoma and ocular hypertension, has a specific market niche. Here, we will delve into the market dynamics and financial trajectory of this drug.

Market Overview

Levobetaxolol hydrochloride, marketed under the trade name Betaxon, is no longer widely available as it has been discontinued. However, understanding its past market dynamics can provide insights into the broader ophthalmic drug market.

Historical Market Presence

When Betaxon was available, it was used to reduce intraocular pressure in patients with glaucoma. The drug was applied topically to the eye and was known for its selective β1 adrenergic receptor antagonism, which reduced aqueous humor production and blood flow to the eye[4].

Competitive Landscape

The ophthalmic drug market, particularly for glaucoma treatments, is highly competitive. Other beta-blockers like timolol maleate and non-beta-blocker alternatives such as prostaglandin analogs and carbonic anhydrase inhibitors compete for market share. The discontinuation of Betaxon has likely shifted market share to these alternative treatments[4].

Financial Performance

Given that Betaxon has been discontinued, its current financial performance is negligible. However, during its active market period, the drug contributed to the overall revenue of its manufacturer. Here are some key points to consider:

  • Revenue Contribution: Although specific revenue figures for Betaxon are not readily available, it was part of a larger market for ophthalmic drugs. The global ophthalmic drugs market is substantial, with segments like glaucoma treatments contributing significantly to overall revenues.
  • Market Size and Growth: The broader ophthalmic drugs market, including glaucoma treatments, is expected to grow due to increasing prevalence of eye disorders and an aging population. However, Betaxon's discontinuation means it no longer participates in this growth[4].

Distribution Channels

Before its discontinuation, Betaxon would have been distributed through various channels, including:

  • Hospital Pharmacies: Often the primary point of distribution for ophthalmic medications prescribed during hospital visits.
  • Retail Pharmacies: Patients could obtain prescriptions for Betaxon from retail pharmacies.
  • Online Pharmacies: Though less common for ophthalmic medications, online pharmacies could also have been a distribution channel[1].

Regional Market Analysis

The market for ophthalmic drugs, including glaucoma treatments, varies by region. Here’s a brief overview of how regional markets might have impacted Betaxon:

  • North America: This region is typically a significant market for ophthalmic drugs due to high healthcare spending and awareness of eye disorders.
  • Europe: Europe also represents a substantial market, with countries like Germany, the UK, and France contributing to the demand for glaucoma treatments.
  • Asia-Pacific: This region is growing rapidly due to an increasing population and rising healthcare standards, though Betaxon's discontinuation means it does not benefit from this growth[1].

Regulatory Environment

The regulatory environment plays a crucial role in the market dynamics of any pharmaceutical drug. For Betaxon, regulatory approvals and compliance were necessary for its market presence. However, the discontinuation suggests that either the drug did not meet regulatory standards or was not economically viable to continue producing.

Patient and Physician Preferences

Patient and physician preferences significantly influence the market for ophthalmic drugs. The preference for drugs with fewer side effects and better efficacy would have impacted Betaxon's market share. Since Betaxon was known for its selective β1 adrenergic receptor antagonism, which reduced respiratory complications compared to non-selective beta-blockers, it might have been preferred by some patients and physicians[4].

Cost and Pricing

The cost of ophthalmic medications can vary widely based on factors such as insurance coverage, treatment plans, and pharmacy choices. Although specific pricing data for Betaxon is not available, it would have been subject to these same variables. The cost of medications is a critical factor in market dynamics, as it affects patient adherence and overall market demand[5].

Key Takeaways

  • Discontinuation Impact: The discontinuation of Betaxon has shifted market share to other glaucoma treatments.
  • Competitive Market: The ophthalmic drug market is highly competitive, with various treatments available for glaucoma.
  • Regional Variations: Market demand varies by region, with North America and Europe being significant markets.
  • Regulatory Compliance: Regulatory approvals and compliance are crucial for any pharmaceutical drug.
  • Patient Preferences: Patient and physician preferences for drugs with better efficacy and fewer side effects influence market dynamics.

FAQs

Q: What is Levobetaxolol Hydrochloride used for? A: Levobetaxolol Hydrochloride is used to treat conditions such as open-angle glaucoma and ocular hypertension by reducing intraocular pressure.

Q: Why was Betaxon discontinued? A: The exact reasons for the discontinuation of Betaxon are not specified, but it could be due to various factors including economic viability, regulatory issues, or market competition.

Q: How does Levobetaxolol Hydrochloride work? A: Levobetaxolol Hydrochloride works by antagonizing β1 adrenergic receptors, reducing aqueous humor production and blood flow to the eye, thereby lowering intraocular pressure[4].

Q: What are the alternatives to Betaxon? A: Alternatives include other beta-blockers like timolol maleate and non-beta-blocker treatments such as prostaglandin analogs and carbonic anhydrase inhibitors.

Q: How does the cost of ophthalmic medications vary? A: The cost of ophthalmic medications can vary based on factors such as insurance coverage, treatment plans, and the pharmacy used[5].

Cited Sources

  1. Transparency Market Research - Levothyroxine Market Size, Share, Analysis to 2034
  2. FDA - Betaxon™ (levobetaxolol hydrochloride ophthalmic suspension) 0.5%
  3. Market Research Future - Levothyroxine Sodium Market Size, Share Trends Report 2032
  4. DrugBank - Levobetaxolol: Uses, Interactions, Mechanism of Action
  5. Medical News Today - Levothyroxine cost 2024: Coupons and more

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