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Last Updated: December 22, 2024

PIPERACILLIN SODIUM - Generic Drug Details


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What are the generic sources for piperacillin sodium and what is the scope of freedom to operate?

Piperacillin sodium is the generic ingredient in five branded drugs marketed by Istituto Bio Ita Spa, Wyeth Pharms Inc, Astral, Eugia Pharma, Eugia Pharma Speclts, Fresenius Kabi, Fresenius Kabi Usa, Hospira Inc, Provepharm Sas, Sagent Pharms Inc, Sandoz, Shandong, Steriscience Speclts, Wockhardt Bio Ag, Wyeth Pharms, and Baxter Hlthcare Corp, and is included in twenty-eight NDAs. Additional information is available in the individual branded drug profile pages.

There are four drug master file entries for piperacillin sodium.

Summary for PIPERACILLIN SODIUM
Recent Clinical Trials for PIPERACILLIN SODIUM

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
M.D. Anderson Cancer CenterPhase 2
Alphacait, LLCPhase 2
Haining Health-Coming Biotech Co., Ltd.Phase 2

See all PIPERACILLIN SODIUM clinical trials

Medical Subject Heading (MeSH) Categories for PIPERACILLIN SODIUM

US Patents and Regulatory Information for PIPERACILLIN SODIUM

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Eugia Pharma PIPERACILLIN AND TAZOBACTAM piperacillin sodium; tazobactam sodium INJECTABLE;INJECTION 217409-002 Oct 12, 2023 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Baxter Hlthcare Corp ZOSYN IN PLASTIC CONTAINER piperacillin sodium; tazobactam sodium INJECTABLE;INJECTION 050750-003 Feb 24, 1998 RX Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Astral PIPERACILLIN AND TAZOBACTAM piperacillin sodium; tazobactam sodium INJECTABLE;INJECTION 212287-003 Jul 29, 2019 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Istituto Bio Ita Spa PIPERACILLIN piperacillin sodium INJECTABLE;INJECTION 065157-001 Jul 12, 2004 RX No Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Fresenius Kabi PIPERACILLIN AND TAZOBACTAM piperacillin sodium; tazobactam sodium INJECTABLE;INJECTION 203719-002 May 18, 2018 AP RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Astral PIPERACILLIN AND TAZOBACTAM piperacillin sodium; tazobactam sodium INJECTABLE;INJECTION 212287-002 Jul 29, 2019 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Sandoz PIPERACILLIN AND TAZOBACTAM piperacillin sodium; tazobactam sodium INJECTABLE;INJECTION 065362-001 Oct 21, 2010 AP RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

PIPERACILLIN SODIUM Market Analysis and Financial Projection Experimental

Piperacillin Sodium Market Dynamics and Financial Trajectory

Introduction to Piperacillin Sodium

Piperacillin sodium is a semisynthetic penicillin antibiotic, widely used to treat serious bacterial infections, including pneumonia, skin infections, and intra-abdominal infections. It is often administered in combination with tazobactam to enhance its efficacy against beta-lactamase-producing bacteria[1].

Market Size and Growth

The global piperacillin sodium market has been experiencing significant growth, driven by the increasing demand for effective antibiotics in healthcare. As of 2021, the market size was estimated at USD 196.92 million and is projected to reach USD 209.80 million by 2028, exhibiting a Compound Annual Growth Rate (CAGR) of 0.91% during the forecast period[4].

Key Drivers of Market Growth

Rising Incidence of Infections

The increasing prevalence of hospital-acquired infections (HAIs) and community-acquired infections has significantly driven the demand for piperacillin sodium. HAIs affect millions of patients annually, necessitating robust antibiotic treatments[1].

Antibiotic Resistance

The global health crisis of antibiotic resistance has heightened the need for effective antibiotics like piperacillin sodium. The World Health Organization (WHO) has identified antibiotic resistance as a major threat, prompting healthcare providers to seek effective treatment alternatives[1].

Expansion of Healthcare Infrastructure

Growing investments in healthcare infrastructure, particularly in emerging markets, have led to increased accessibility to antibiotics. This expansion is crucial for managing bacterial infections effectively[1].

Regional Market Dynamics

North America

North America holds a significant market share due to advanced healthcare infrastructure, high healthcare expenditure, and a robust pharmaceutical industry. The region's well-developed healthcare system ensures a steady demand for piperacillin sodium[1].

Europe

European countries are witnessing an increasing emphasis on antibiotic stewardship programs, which encourage the appropriate use of antibiotics, thereby boosting demand for effective treatments like piperacillin sodium[1].

Asia-Pacific

The Asia-Pacific region is expected to exhibit the highest growth rate, driven by rising infection rates, increasing healthcare investments, and a growing patient population. This region presents substantial opportunities for market expansion[1].

Market Segmentation

By Type

The market is segmented into piperacillin and piperacillin combined with tazobactam. The combination therapy is particularly effective against beta-lactamase-producing bacteria, making it a preferred choice in many clinical settings[4].

By Application

The market is segmented into piperacillin sodium injection and piperacillin sodium compound injection. These formulations cater to different clinical needs and patient populations, ensuring a broad market reach[4].

Competitive Landscape

The global piperacillin sodium market is competitive, with key players including Qilu Pharmaceutical, Pfizer Healthcare, Fresenius Kabi AG, Aurobindo Pharma, and Sandoz Inc. These companies are involved in various strategies such as research and development, manufacturing expansions, and strategic partnerships to enhance their market positions[4].

Innovations and Trends

Drug Formulations

Recent advancements in drug formulations, such as extended-release formulations and combination therapies with beta-lactamase inhibitors, are enhancing the efficacy and safety of piperacillin sodium. These innovations are crucial in combating resistant strains of bacteria[1].

Generic Alternatives

As patents for branded piperacillin sodium products expire, the market is witnessing a surge in generic alternatives. This shift is expected to make the drug more accessible and affordable, particularly in low- and middle-income countries[1].

Partnerships and Collaborations

Collaborations between pharmaceutical companies and healthcare institutions are becoming increasingly common. These partnerships aim to facilitate research and development efforts, improve antibiotic stewardship, and enhance education on appropriate antibiotic usage among healthcare professionals[1].

Financial Trajectory

Market Forecast

The market is forecasted to grow steadily, albeit at a moderate CAGR of 0.91% from 2021 to 2028. This growth is supported by the increasing demand for antibiotics and the expanding healthcare infrastructure in emerging markets[4].

Investment Opportunities

  • Research and Development: Investing in R&D for new formulations and delivery mechanisms can yield high returns as the demand for effective antibiotics continues to rise.
  • Manufacturing Capabilities: Expanding manufacturing facilities to meet increased demand can benefit from economies of scale, leading to improved profitability.
  • Emerging Markets: Investing in emerging markets, particularly in Asia-Pacific and Latin America, offers substantial growth potential due to rising healthcare needs and increasing access to antibiotics[1].

Challenges and Restraints

Antibiotic Resistance

Antibiotic resistance poses a significant threat to public health, making infections harder to treat and leading to longer hospital stays, higher medical costs, and increased mortality. This challenge necessitates continuous innovation and stewardship in antibiotic use[1].

Regulatory Environment

The market is subject to stringent regulatory requirements, which can impact the approval and distribution of piperacillin sodium products. Compliance with these regulations is crucial for market success[4].

Key Takeaways

  • The global piperacillin sodium market is driven by increasing demand for effective antibiotics and expanding healthcare infrastructure.
  • The market is segmented by type and application, with combination therapies being particularly effective.
  • Key regions include North America, Europe, and the Asia-Pacific, with the latter expected to show the highest growth rate.
  • Innovations in drug formulations and generic alternatives are key trends.
  • Investment opportunities exist in R&D, manufacturing, and emerging markets.
  • Antibiotic resistance and regulatory challenges are significant market restraints.

FAQs

  1. What is piperacillin sodium used for? Piperacillin sodium is used to treat serious bacterial infections, including pneumonia, skin infections, and intra-abdominal infections, often in combination with tazobactam[1].

  2. What drives the demand for piperacillin sodium? The demand is driven by the rising incidence of infections, the challenge of antibiotic resistance, and the expansion of healthcare infrastructure[1].

  3. Which regions are key markets for piperacillin sodium? North America, Europe, and the Asia-Pacific are significant markets, with the Asia-Pacific region expected to exhibit the highest growth rate[1].

  4. What are the recent trends in the piperacillin sodium market? Recent trends include innovations in drug formulations, the rise of generic alternatives, and partnerships between pharmaceutical companies and healthcare institutions[1].

  5. What are the investment opportunities in the piperacillin sodium market? Investment opportunities include research and development, expanding manufacturing capabilities, and targeting emerging markets[1].

Cited Sources

  1. Market Research Intellect - "Piperacillin Sodium Market Size And Projection"
  2. PMC - "Jejunal perforation secondary to blind insertion of peritoneal dialysis"
  3. IMARC Group - "Piperacillin Tazobactam Manufacturing Plant Report 2024"
  4. Business Wire - "Global Piperacillin Sodium (CAS 59703 84 3) Market Report 2022"
  5. Market Research Intellect - "Marktgröße, Umfang und Prognosebericht zu Piperacillin-Natrium"

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