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Last Updated: April 5, 2025

Acetic acid, glacial - Generic Drug Details


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What are the generic drug sources for acetic acid, glacial and what is the scope of freedom to operate?

Acetic acid, glacial is the generic ingredient in fifteen branded drugs marketed by Actavis Mid Atlantic, Chartwell Rx, Kv Pharm, Rising, Sciegen Pharms Inc, Taro, Warner Chilcott, Hikma, B Braun, Baxter Hlthcare, Icu Medical Inc, Bausch And Lomb, Pharmafair, Bayer Pharms, Cosette, Wockhardt, and Saptalis Pharms, and is included in twenty-four NDAs. Additional information is available in the individual branded drug profile pages.

Seven suppliers are listed for this compound.

Summary for acetic acid, glacial
Recent Clinical Trials for acetic acid, glacial

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
National Institute of PerinatologyPhase 4
National Council of Science and Technology, MexicoPhase 4

See all acetic acid, glacial clinical trials

US Patents and Regulatory Information for acetic acid, glacial

ApplicantTradenameGeneric NameDosageNDAApproval DateTETypeRLDRSPatent No.Patent ExpirationProductSubstanceDelist Req.Exclusivity Expiration
Saptalis Pharms VOSOL HC acetic acid, glacial; hydrocortisone SOLUTION/DROPS;OTIC 012770-001 Approved Prior to Jan 1, 1982 AT RX Yes Yes ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
Taro HYDROCORTISONE AND ACETIC ACID acetic acid, glacial; hydrocortisone SOLUTION/DROPS;OTIC 088759-001 Mar 4, 1985 AT RX Yes Yes ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
Rising ACETIC ACID acetic acid, glacial SOLUTION/DROPS;OTIC 207280-001 Mar 9, 2018 AT RX No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>TE>Type>RLD>RS>Patent No.>Patent Expiration>Product>Substance>Delist Req.>Exclusivity Expiration
Showing 1 to 3 of 3 entries

Glacial Acetic Acid Market Dynamics and Financial Trajectory

Market Overview

The global glacial acetic acid market is poised for significant growth, driven by various factors including increasing demand from key end-user industries and the pursuit of sustainable production methods.

Market Size and Growth

The global glacial acetic acid market is expected to grow substantially over the forecast period. As of 2023, the market size was estimated at 1,723.22 kilotons, and it is projected to reach 2,081.48 kilotons by 2028, growing at a CAGR of 3.85%[1].

In terms of value, the market was valued at USD 8,264.4 million in 2023 and is anticipated to reach USD 16,521.8 million by 2034, with a CAGR of 6.5% during the forecast period[5].

Regional Dynamics

Asia-Pacific Dominance

The Asia-Pacific region dominates the global glacial acetic acid market, accounting for the largest consumption. Countries such as China, India, and Japan are the key drivers of this growth. The region's expanding economy, rising middle class, and increasing demand for packaged goods are significant factors contributing to this dominance[1][5].

Other Regions

While Asia-Pacific leads, other regions such as North America and Europe also contribute to the market growth, albeit at a slower pace. The demand in these regions is driven by the chemical, pharmaceutical, and food industries.

Key Drivers of Growth

Increasing Demand for Vinyl Acetate Monomer and PTA

The growing demand for vinyl acetate monomer (VAM) and purified terephthalic acid (PTA) from industries such as packaging, paints, and coatings is a major driver of the glacial acetic acid market. PTA, in particular, is crucial for the production of polyethylene terephthalate (PET), which is widely used in packaging[1].

Sustainable Production Methods

There is a growing interest in producing glacial acetic acid from biomass, which offers a sustainable and environmentally friendly alternative to traditional petrochemical routes. This method, involving bioconversion using ethyl acetate or alamine, has been shown to be economically viable and energy-efficient[2].

Expanding Chemical Sector

The continuous expansion of the chemical sector, particularly in Asia-Pacific, is a key factor driving the demand for glacial acetic acid. The acid is an essential intermediate in the production of various chemicals, textiles, dyes, and paints[5].

Challenges and Hindrances

Health Hazards

Glacial acetic acid poses significant health hazards, which can hinder market growth. The acid is corrosive and can cause severe burns and respiratory issues, necessitating stringent safety measures and regulations[1].

Supply Chain Disruptions

The COVID-19 pandemic highlighted the vulnerability of the glacial acetic acid market to supply chain disruptions. Factory closures and lockdowns led to temporary declines in demand and production. However, the market rebounded quickly as restrictions eased[1][5].

Market Concentration and Key Players

Market Fragmentation

The global glacial acetic acid market is partially fragmented, with several major players competing in the market. Key players include Celanese Corporation, Eastman Chemical Company, INEOS, Jiangsu Thorpe (Group) Co., Ltd., and LyondellBasell Industries Holdings B.V.[1].

Investment in Research and Development

Companies are investing heavily in research and development to optimize production processes, reduce costs, and make domestic production more competitive. For instance, INEOS is planning to build a world-scale acetic acid manufacturing facility on the Gulf Coast of the United States[1].

End-Use Industries

Packaging Industry

Glacial acetic acid is a major raw material for producing PTA, which is used extensively in the packaging industry. The growing demand for packaging worldwide, particularly in Asia-Pacific, drives the demand for glacial acetic acid[1].

Textile Industry

In the textile industry, glacial acetic acid is used as a buffering agent in dyeing cloth and for printing designs. It is also used in the production of acetic anhydride, which is further used in synthetic textiles and photographic films[1].

Pharmaceutical and Food Industries

The acid is used in various pharmaceutical applications and as a preservative and condiment in the food industry. The demand from these sectors has been steady, especially during the COVID-19 pandemic[5].

Financial Trajectory

Revenue Projections

The global glacial acetic acid market is projected to grow from USD 8,801.6 million in 2024 to USD 16,521.8 million by 2034, with a CAGR of 6.5% during the forecast period[5].

Cost Dynamics

The cost of manufacturing glacial acetic acid can be significantly impacted by changes in natural gas prices and the adoption of alternative feedstocks such as bio-based acetic acid. Trade conflicts and tariffs can also affect import/export costs and disrupt global supply networks[5].

Pricing Factors

The price of glacial acetic acid can be influenced by several factors, including supply and demand dynamics, manufacturing issues, inventory levels, feedstock costs, and geopolitical considerations. High inventory levels and competition among manufacturers can lead to price reductions, while unexpected plant shutdowns and production problems can surge prices[5].

Sustainability and Environmental Impact

Bio-Based Production

The shift towards bio-based production methods is gaining traction due to environmental concerns. Governments are implementing stringent environmental laws and offering incentives for bio-based acetic acid production. This trend is expected to create novel markets and drive growth in the sector[5].

Consumer Awareness

Growing consumer awareness of environmental issues is influencing purchase decisions, with eco-conscious consumers favoring products made from sustainable materials. Companies that can demonstrate the sustainability credentials of their glacial acetic acid are likely to attract these consumers[5].

"Growing awareness of environmental issues is highly influencing consumers' purchase decisions. Organizations that can demonstrate the sustainability credentials of glacial acetic acid are likely to attract eco-conscious consumers."[5]

Key Takeaways

  • The global glacial acetic acid market is expected to grow at a CAGR of 6.5% from 2024 to 2034.
  • Asia-Pacific dominates the market due to its expanding economy and rising demand for packaged goods.
  • The demand for vinyl acetate monomer and PTA from packaging, paints, and coatings is a major driver.
  • Sustainable production methods, such as bioconversion from biomass, are gaining traction.
  • Health hazards and supply chain disruptions are significant challenges.
  • Key players are investing in research and development to optimize production processes.

FAQs

What is the current market size of the glacial acetic acid market?

The global glacial acetic acid market size was valued at USD 8,264.4 million in 2023 and is projected to reach USD 16,521.8 million by 2034[5].

Which region dominates the glacial acetic acid market?

The Asia-Pacific region dominates the global glacial acetic acid market, with countries such as China, India, and Japan being the key drivers[1][5].

What are the major drivers of the glacial acetic acid market?

The growing demand for vinyl acetate monomer and PTA, expanding chemical sector, and the pursuit of sustainable production methods are major drivers of the market[1][5].

Who are the key players in the glacial acetic acid market?

Key players include Celanese Corporation, Eastman Chemical Company, INEOS, Jiangsu Thorpe (Group) Co., Ltd., and LyondellBasell Industries Holdings B.V.[1].

How is the shift to bio-based production impacting the market?

The shift to bio-based production is expected to create novel markets and drive growth in the sector due to environmental concerns and government incentives[5].

What are the potential challenges facing the glacial acetic acid market?

Health hazards, supply chain disruptions, and fluctuations in raw material costs are significant challenges facing the market[1][5].

Sources

  1. Mordor Intelligence: Glacial Acetic Acid Market - Growth Trends & Major Manufacturers.
  2. PubMed: Techno-Economic Analysis of Producing Glacial Acetic Acid from Biomass.
  3. Zion Market Research: Glacial Acetic Acid Market Size, Share, Growth, Trends, and Forecast.
  4. PR Newswire: Glacial Acetic Acid Sales to Total USD 16521.8 Million by 2034.
  5. Future Market Insights: Glacial Acetic Acid Market Size, Growth & Trends by 2034.

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