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Last Updated: March 26, 2025

Ivermectin - Generic Drug Details


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What are the generic drug sources for ivermectin and what is the scope of freedom to operate?

Ivermectin is the generic ingredient in four branded drugs marketed by Padagis Israel, Teva Pharms Usa, Zydus Lifesciences, Galderma Labs Lp, Taro, Arbor Pharms Llc, Edenbridge Pharms, Rubicon, Senores Pharms, and Merck Sharp Dohme, and is included in eleven NDAs. There are five patents protecting this compound and two Paragraph IV challenges. Additional information is available in the individual branded drug profile pages.

Ivermectin has forty-five patent family members in sixteen countries.

There are five drug master file entries for ivermectin. Twenty-three suppliers are listed for this compound.

Drug Prices for ivermectin

See drug prices for ivermectin

Recent Clinical Trials for ivermectin

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
Public Health Laboratory Ivo de CarneriPhase 2
National Public Health Institute of LiberiaPhase 2
Vector Borne & Neglected Tropical Disease Control Division, Ministry of Health, UgandaPhase 3

See all ivermectin clinical trials

Pharmacology for ivermectin
Medical Subject Heading (MeSH) Categories for ivermectin
Paragraph IV (Patent) Challenges for IVERMECTIN
Tradename Dosage Ingredient Strength NDA ANDAs Submitted Submissiondate
SKLICE Lotion ivermectin 0.50% 202736 1 2017-09-01
SOOLANTRA Cream ivermectin 1% 206255 1 2016-12-30

US Patents and Regulatory Information for ivermectin

ApplicantTradenameGeneric NameDosageNDAApproval DateTETypeRLDRSPatent No.Patent ExpirationProductSubstanceDelist Req.Exclusivity Expiration
Merck Sharp Dohme STROMECTOL ivermectin TABLET;ORAL 050742-001 Nov 22, 1996 DISCN Yes No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
Galderma Labs Lp SOOLANTRA ivermectin CREAM;TOPICAL 206255-001 Dec 19, 2014 AB RX Yes Yes 10,206,939 ⤷  Try for Free ⤷  Try for Free
Padagis Israel IVERMECTIN ivermectin CREAM;TOPICAL 210225-001 Apr 13, 2020 AB RX No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
Taro IVERMECTIN ivermectin LOTION;TOPICAL 210720-001 May 6, 2020 OTC No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
Teva Pharms Usa IVERMECTIN ivermectin LOTION;TOPICAL 212485-001 Mar 21, 2022 DISCN No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
Rubicon IVERMECTIN ivermectin TABLET;ORAL 215922-001 Jan 22, 2025 AB RX No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>TE>Type>RLD>RS>Patent No.>Patent Expiration>Product>Substance>Delist Req.>Exclusivity Expiration
Showing 1 to 6 of 6 entries

Expired US Patents for ivermectin

ApplicantTradenameGeneric NameDosageNDAApproval DatePatent No.Patent Expiration
Galderma Labs Lp SOOLANTRA ivermectin CREAM;TOPICAL 206255-001 Dec 19, 2014 11,033,565 ⤷  Try for Free
Galderma Labs Lp SOOLANTRA ivermectin CREAM;TOPICAL 206255-001 Dec 19, 2014 8,093,219 ⤷  Try for Free
Galderma Labs Lp SOOLANTRA ivermectin CREAM;TOPICAL 206255-001 Dec 19, 2014 8,815,816 ⤷  Try for Free
Galderma Labs Lp SOOLANTRA ivermectin CREAM;TOPICAL 206255-001 Dec 19, 2014 8,470,788 ⤷  Try for Free
Galderma Labs Lp SOOLANTRA ivermectin CREAM;TOPICAL 206255-001 Dec 19, 2014 5,952,372 ⤷  Try for Free
Galderma Labs Lp SOOLANTRA ivermectin CREAM;TOPICAL 206255-001 Dec 19, 2014 8,080,530 ⤷  Try for Free
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>Patent No.>Patent Expiration
Showing 1 to 6 of 6 entries

International Patents for ivermectin

CountryPatent NumberTitleEstimated Expiration
Brazil 112016000350 métodos de tratamento de lesões inflamatórias da rosácea e usos de uma composição farmacêutica ⤷  Try for Free
China 111494399 ⤷  Try for Free
Hong Kong 1223842 ⤷  Try for Free
Mexico 2016000122 TRATAMIENTO DE ROSACEA PAPULOPUSTULAR CON INVERMECTINA. (TREATMENT OF PAPULOPUSTULAR ROSACEA WITH IVERMECTIN.) ⤷  Try for Free
Russian Federation 2633076 ЛЕЧЕНИЕ ПАПУЛОПУСТУЛЕЗНОЙ РОЗАЦЕА ИВЕРМЕКТИНОМ (PAPULOPUSTULAR ROSACEA TREATMENT BY IVERMECTIN) ⤷  Try for Free
Singapore 11201510635P TREATMENT OF PAPULOPUSTULAR ROSACEA WITH IVERMECTIN ⤷  Try for Free
>Country>Patent Number>Title>Estimated Expiration
Showing 1 to 6 of 6 entries

Supplementary Protection Certificates for ivermectin

Patent NumberSupplementary Protection CertificateSPC CountrySPC ExpirationSPC Description
1620113 122015000079 Germany ⤷  Try for Free PRODUCT NAME: IVERMECTIN ZU SEINER VERWENDUNG FUER DIE BEHANDLUNG VON ROSAZEA; NAT. REGISTRATION NO/DATE: 92429.00.00 20150429; FIRST REGISTRATION: MALTA MA 117/01101 20150402
1620113 2015/046 Ireland ⤷  Try for Free PRODUCT NAME: IVERMECTIN; NAT REGISTRATION NO/DATE: PA0590/028/001 20150424; FIRST REGISTRATION NO/DATE: MA117/01101 20150402
1620113 300756 Netherlands ⤷  Try for Free PRODUCT NAME: IVERMECTINE VOOR TOEPASSING IN DE BEHANDELING VAN ROSACEA; NATIONAL REGISTRATION NO/DATE: RVG 115310 20150504; FIRST REGISTRATION: MT MA117/01101 20150402
1620113 56/2015 Austria ⤷  Try for Free PRODUCT NAME: IVERMECTIN; NAT. REGISTRATION NO/DATE: 136170 20150602; FIRST REGISTRATION: MT MA 117/01101 20150402
1620113 C 2015 036 Romania ⤷  Try for Free PRODUCT NAME: IVERMECTINA; NATIONAL AUTHORISATION NUMBER: RO7674/2015/01, RO7674/2015/02, RO7674/2015/03, RO7674/2015/04, RO7674/2015/05; DATE OF NATIONAL AUTHORISATION: 20150526; NUMBER OF FIRST AUTHORISATION IN EUROPEAN ECONOMIC AREA (EEA): MALTA MA117/01101; DATE OF FIRST AUTHORISATION IN EEA: 20150402
1620113 C300756 Netherlands ⤷  Try for Free PRODUCT NAME: IVERMECTINE VOOR TOEPASSING IN; NAT. REGISTRATION NO/DATE: RVG 115310 20150504; FIRST REGISTRATION: MA117/01101 20150402
>Patent Number>Supplementary Protection Certificate>SPC Country>SPC Expiration>SPC Description
Showing 1 to 6 of 6 entries

Market Dynamics and Financial Trajectory for Ivermectin

Market Overview

The global ivermectin market has been experiencing significant growth, driven by various factors including the rise in parasitic infections and its misuse during the COVID-19 pandemic.

  • As of 2022, the global ivermectin market valued at USD 293.95 million, and it is projected to reach USD 398.46 million by 2028, with a Compound Annual Growth Rate (CAGR) of 5.2% during the forecast period[1].

Market Drivers

Several key factors are driving the growth of the ivermectin market:

  • Prevalence of Parasitic Infections: The increasing prevalence of parasitic infections such as ascariasis, lymphatic filariasis, and river blindness in both humans and animals is a major driver. For instance, in dogs, the prevalence of roundworms, hookworms, and whipworms ranges significantly, necessitating the use of anthelmintic drugs like ivermectin[1].

  • Veterinary Use: Ivermectin is widely used in veterinary medicine, which contributes substantially to its market growth. The demand for ivermectin in treating parasitic infections in livestock and pets continues to rise[3].

  • Misuse During COVID-19: Although ivermectin has no proven efficacy against COVID-19, its prescriptions surged during the pandemic, leading to significant spending by insurers. This misuse, however, is considered wasteful and not aligned with economic theory or medical evidence[2][5].

Market Segmentation

The ivermectin market is segmented based on several criteria:

  • Type: Ivermectin is available in various forms, including powder and liquid, each catering to different applications[3][4].

  • Application: The market is divided into human medicine and veterinary medicine. The veterinary segment is particularly robust due to the widespread use of ivermectin in animal health care[3][4].

  • Geography: The market is analyzed across different regions such as North America, Europe, Asia-Pacific, South America, and the Middle East and Africa. Each region has its own market dynamics and growth prospects[3][4].

Financial Trajectory

The financial outlook for the ivermectin market is promising but complex due to various factors:

  • Global Market Size: The global ivermectin market is expected to grow from USD 293.95 million in 2022 to USD 398.46 million by 2028, with a CAGR of 5.2%[1].

  • Regional Markets: The European market, for example, is forecasted to reach USD 213.7 million by 2030, growing at a CAGR of 7.3% from 2024 to 2030[4].

  • Wasteful Spending: The misuse of ivermectin for COVID-19 has led to significant wasteful spending by insurers. Estimates suggest that insurers spent nearly $130 million annually on ivermectin prescriptions for COVID-19, which is considered ineffective care[2][5].

Key Players

The ivermectin market is dominated by several key players:

  • Merck & Co. Inc.: One of the original developers and major suppliers of ivermectin.
  • CSPC Pharmaceutical Group Limited: A significant player in the Asian market.
  • Jubilant Life Sciences Ltd.: Known for its extensive range of pharmaceutical products, including ivermectin.
  • Boehringer Ingelheim International GmbH: A global pharmaceutical company with a strong presence in the veterinary segment.
  • Other notable players include Hero Pharmaceutical, HuBei YuanCheng SaiChuang, ENN, and LAND[3][4].

Market Dynamics

The market dynamics are influenced by several factors:

  • Drivers: Increasing demand due to parasitic infections, advancements in pharmaceutical technology, and the expanding veterinary market.
  • Restraints: Regulatory challenges, the misuse of ivermectin for COVID-19, and the potential for resistance development in parasites.
  • Opportunities: Growing awareness of animal health, expansion into new markets, and the development of new formulations.
  • Challenges: Ensuring the responsible use of ivermectin, managing wasteful spending, and addressing regulatory hurdles[3].

Impact of COVID-19

The COVID-19 pandemic had a significant impact on the ivermectin market, albeit largely negative:

  • Increased Prescriptions: Despite having no proven efficacy against COVID-19, ivermectin prescriptions surged, leading to substantial wasteful spending by insurers.
  • Economic Implications: The annual spending on ivermectin for COVID-19 was estimated at $129.7 million, which is higher than spending on some low-value medical services[2][5].

Future Outlook

The future of the ivermectin market looks promising, especially in the veterinary segment:

  • Growth Projections: The market is expected to continue growing, driven by the increasing need for effective treatments against parasitic infections.
  • Regulatory Measures: There is a need for stricter regulatory measures to prevent the misuse of ivermectin and ensure its responsible use.
  • Innovation: The development of new formulations and delivery methods could further boost the market[3][4].

Key Takeaways

  • The global ivermectin market is growing, driven by the rise in parasitic infections and veterinary use.
  • The misuse of ivermectin for COVID-19 has led to significant wasteful spending.
  • Key players dominate the market, and regional markets show varying growth rates.
  • Regulatory measures and innovation are crucial for the future growth and responsible use of ivermectin.

FAQs

Q: What is the current market size of the global ivermectin market? A: As of 2022, the global ivermectin market valued at USD 293.95 million[1].

Q: What is the projected growth rate of the ivermectin market? A: The market is expected to grow at a CAGR of 5.2% from 2022 to 2028[1].

Q: Why did ivermectin prescriptions surge during the COVID-19 pandemic? A: Despite having no proven efficacy against COVID-19, ivermectin prescriptions increased significantly, leading to wasteful spending by insurers[2][5].

Q: Who are the major players in the ivermectin market? A: Major players include Merck & Co. Inc., CSPC Pharmaceutical Group Limited, Jubilant Life Sciences Ltd., and Boehringer Ingelheim International GmbH, among others[3][4].

Q: What are the main segments of the ivermectin market? A: The market is segmented by type (powder, liquid), application (human medicine, veterinary medicine), and geography (North America, Europe, Asia-Pacific, etc.)[3][4].

Sources

  1. Global Ivermectin Market Research Report 2023-Competitive Analysis, Status and Outlook by Type, Downstream Industry, and Geography, Forecast to 2029 - Market Research.
  2. US Insurer Spending on Ivermectin Prescriptions for COVID-19 - JAMA.
  3. Global Ivermectin API Sales Market Size, Scope And Forecast Report - Market Research Intellect.
  4. Ivermectin - Market, Report Size, Worth, Revenue, Growth, Industry - Valuates Reports.
  5. Study: Insurers spend nearly $130M a year on ivermectin prescriptions - Fierce Healthcare.

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