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Last Updated: December 25, 2024

Methenamine hippurate - Generic Drug Details


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What are the generic drug sources for methenamine hippurate and what is the scope of patent protection?

Methenamine hippurate is the generic ingredient in three branded drugs marketed by Esjay Pharma, Aurobindo Pharma Ltd, Impax Labs Inc, Jubilant Cadista, Micro Labs, Novast Labs, and Alvogen, and is included in seven NDAs. Additional information is available in the individual branded drug profile pages.

There are ten drug master file entries for methenamine hippurate. Nine suppliers are listed for this compound.

Summary for methenamine hippurate
Drug Prices for methenamine hippurate

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Recent Clinical Trials for methenamine hippurate

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SponsorPhase
University of Texas Southwestern Medical CenterPhase 4
Washington University School of MedicinePhase 4
University of OsloPhase 4

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Medical Subject Heading (MeSH) Categories for methenamine hippurate
Anatomical Therapeutic Chemical (ATC) Classes for methenamine hippurate

US Patents and Regulatory Information for methenamine hippurate

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Micro Labs METHENAMINE HIPPURATE methenamine hippurate TABLET;ORAL 212172-001 Aug 1, 2019 AB RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Alvogen UREX methenamine hippurate TABLET;ORAL 016151-001 Approved Prior to Jan 1, 1982 AB RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Impax Labs Inc METHENAMINE HIPPURATE methenamine hippurate TABLET;ORAL 076411-001 Jun 20, 2003 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Methenamine hippurate Market Analysis and Financial Projection Experimental

Methenamine Hippurate Tablets Market Dynamics and Financial Trajectory

Introduction to Methenamine Hippurate Tablets

Methenamine hippurate tablets are a crucial medication used for the prevention and treatment of urinary tract infections (UTIs) caused by specific bacteria. These tablets have gained significant attention in recent years due to their effectiveness and the rising prevalence of UTIs globally.

Market Size and Growth

The global methenamine hippurate tablets market has demonstrated robust growth in recent years. As of 2022, the market size was valued at approximately $8.91 billion. It is projected to grow to $9.63 billion in 2024 and further to $14.74 billion by 2030, with a compound annual growth rate (CAGR) of around 6.51% between 2023 and 2030[4][5].

Historic Market Growth

The historic growth of the methenamine hippurate tablets market can be attributed to several factors, including traditional UTI treatment methods, concerns over antibiotic resistance, clinical validation, physician prescription patterns, and patient preference for non-antibiotic solutions. The market has seen a steady increase from 2018 to 2023, driven by these factors[1].

Forecast Market Growth

The forecast period from 2023 to 2030 is expected to see continued strong growth. Key drivers include the increasing prevalence of UTIs, rising concerns over antibiotic resistance, advancements in UTI management, a focus on preventive healthcare, and ongoing clinical trials and research. The market is anticipated to reach $14.74 billion by 2030, with North America leading the regional growth due to high awareness and robust medical infrastructure[4][5].

Segmentation of the Market

By Type

The methenamine hippurate tablets market is segmented by type into 20 tablets or bottle and 6 tablets or bottle. These different packaging options cater to various patient needs and preferences, influencing market dynamics[1][4].

By Distribution Channel

The market is segmented by distribution channels into hospital pharmacy, online pharmacy, and retail pharmacy. Hospital pharmacies have been the largest distribution channel, accounting for the highest market share due to their large patient populations and bulk orders. Retail pharmacies also play a significant role, while online pharmacies face regulatory and safety challenges that limit their growth[1][5].

By Application

The application segmentation includes uncomplicated UTIs and healthcare-associated UTIs. Uncomplicated UTIs have been the leading application segment, as these infections are more common and can often be treated effectively with methenamine hippurate tablets[1][4].

By End User

The end-user segmentation includes hospitals, homecare, specialty clinics, and other end users. Hospitals and homecare settings are significant end users, reflecting the broad range of treatment environments where these tablets are utilized[1].

Drivers of the Market

Increasing Prevalence of UTIs

The rising cases of urinary tract infections are a major driver of the methenamine hippurate tablets market. UTIs are common, especially among women, and the increasing female population globally contributes to the growing demand for these tablets[1][4].

Antibiotic Resistance Concerns

The growing concern over antibiotic resistance has led to a preference for non-antibiotic treatments like methenamine hippurate. This shift is driven by the need to reduce the overuse of antibiotics and mitigate the risk of antibiotic-resistant bacteria[1][4].

Clinical Validation and Research

Clinical trials and research have validated the effectiveness of methenamine hippurate tablets, further boosting their adoption. Studies have shown that methenamine hippurate is often less costly and more effective than antibiotic prophylaxis in managing recurrent UTIs[2].

Focus on Preventive Healthcare

There is a growing focus on preventive healthcare, which includes the use of methenamine hippurate tablets to prevent recurring UTIs. This preventive approach is driving market growth as more patients and healthcare providers opt for proactive treatment strategies[1][4].

Restraints of the Market

Adverse Effects

Despite the benefits, methenamine hippurate tablets can have adverse effects such as gastrointestinal disturbances, skin rashes, and allergic reactions. These side effects can limit market growth unless manufacturers can develop formulations with minimal unwanted medical impacts[4].

Limited Awareness and Availability

In underdeveloped economies, there is limited awareness among patients about the benefits of methenamine hippurate tablets. Additionally, the availability of these tablets is restricted in some regions, posing a challenge to market expansion[4].

Alternative Medicines and Patent Expiry

The availability of alternative medicines and the potential expiry of patents can also hinder market growth. These factors can reduce the market share of methenamine hippurate tablets if not addressed through innovative strategies and product development[4].

Cost-Effectiveness

Studies have shown that methenamine hippurate is often more cost-effective than antibiotic prophylaxis. A multicentre, open-label, randomised trial in the UK found that methenamine hippurate was less costly and more effective, with a higher probability of being considered cost-effective when the benefits of reduced antibiotic use were included[2].

Strategic Collaborations

Major companies in the methenamine hippurate tablets market are engaging in strategic collaborations to enhance their market presence. For example, EQL Pharma AB collaborated with Dr. Pfleger Arzneimittel GmbH to launch methenamine hippurate tablets with a new brand, highlighting the importance of partnerships in driving market growth[1].

Regional Analysis

North America

North America is expected to lead the global methenamine hippurate tablets market due to high awareness among the population, robust medical infrastructure, and significant investments in research and development. The US and Canada are key contributors to this regional growth[4][5].

Europe

Europe is also a significant market, driven by the rising demand for preventive care and over-the-counter medications. The presence of key pharmaceutical industry players investing in new product development further supports the regional growth[5].

Asia Pacific and Other Regions

The Asia Pacific region, including countries like China, Japan, and India, is expected to see growth driven by increasing healthcare expenditure and a growing demand for healthcare services. However, regions like Africa may face challenges due to limited awareness and inadequate medical infrastructure[4][5].

Key Takeaways

  • The global methenamine hippurate tablets market is projected to grow significantly, reaching $14.74 billion by 2030.
  • The market is driven by the increasing prevalence of UTIs, concerns over antibiotic resistance, and a focus on preventive healthcare.
  • Hospital pharmacies are the largest distribution channel, while uncomplicated UTIs are the leading application segment.
  • The market faces restraints such as adverse effects, limited awareness, and availability issues in underdeveloped economies.
  • Strategic collaborations and cost-effectiveness are key factors enhancing market growth.

FAQs

What is the current market size of methenamine hippurate tablets?

The global methenamine hippurate tablets market size was valued at approximately $8.91 billion in 2022[4].

What is the projected growth rate of the methenamine hippurate tablets market?

The market is expected to grow at a CAGR of around 6.51% between 2023 and 2030[4][5].

Which region is expected to lead the global methenamine hippurate tablets market?

North America is expected to lead the global market due to high awareness and robust medical infrastructure[4][5].

What are the main drivers of the methenamine hippurate tablets market?

The main drivers include the increasing prevalence of UTIs, concerns over antibiotic resistance, clinical validation, and a focus on preventive healthcare[1][4].

What are the potential restraints to the growth of the methenamine hippurate tablets market?

Potential restraints include adverse effects, limited awareness and availability in underdeveloped economies, and the availability of alternative medicines[4].

How do strategic collaborations impact the methenamine hippurate tablets market?

Strategic collaborations enhance market growth by allowing companies to leverage each other’s strengths and resources, leading to new product launches and expanded market reach[1].

Sources

  1. The Business Research Company. Methenamine Hippurate Tablets Global Market Report 2024.
  2. PubMed. Cost-effectiveness of methenamine hippurate compared with antibiotic prophylaxis in the management of recurrent urinary tract infections.
  3. OpenPR. Methenamine Hippurate Tablets Market Size, Share Analysis.
  4. GlobeNewswire. Global Methenamine Hippurate Tablets Market Size is Anticipated to Acquire $14.74 Billion by 2030 With CAGR of 6.51%.
  5. Zion Market Research. Methenamine Market Size, Share, Analysis and Forecast 2030.

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