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Last Updated: April 11, 2025

Pyrvinium pamoate - Generic Drug Details


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What are the generic sources for pyrvinium pamoate and what is the scope of freedom to operate?

Pyrvinium pamoate is the generic ingredient in one branded drug marketed by Parke Davis and is included in two NDAs. Additional information is available in the individual branded drug profile pages.

Summary for pyrvinium pamoate
US Patents:0
Tradenames:1
Applicants:1
NDAs:2
Raw Ingredient (Bulk) Api Vendors: 41
Clinical Trials: 1
Patent Applications: 1,836
DailyMed Link:pyrvinium pamoate at DailyMed
Recent Clinical Trials for pyrvinium pamoate

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US Patents and Regulatory Information for pyrvinium pamoate

ApplicantTradenameGeneric NameDosageNDAApproval DateTETypeRLDRSPatent No.Patent ExpirationProductSubstanceDelist Req.Exclusivity Expiration
Parke Davis POVAN pyrvinium pamoate SUSPENSION;ORAL 011964-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
Parke Davis POVAN pyrvinium pamoate TABLET;ORAL 012485-002 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>TE>Type>RLD>RS>Patent No.>Patent Expiration>Product>Substance>Delist Req.>Exclusivity Expiration
Showing 1 to 2 of 2 entries

Market Dynamics and Financial Trajectory of Pyrvinium Pamoate

Introduction

Pyrvinium pamoate, a drug traditionally used as an antihelminthic agent, is experiencing a significant transformation in its market dynamics and financial trajectory. This shift is driven by its emerging applications in oncology and other therapeutic areas, along with growing demand for effective and safe treatments for parasitic infections.

Market Size and Growth Prospects

The Pyrvinium Pamoate market is anticipated to witness substantial growth, with projections indicating a valuation of USD 19.33 Billion by 2024 and expected to reach USD 35.06 Billion by 2031. This growth is fueled by a compound annual growth rate (CAGR) of 8.88% from 2024 to 2031[1].

Key Drivers of Market Growth

Several factors are driving the growth of the Pyrvinium Pamoate market:

Increasing Prevalence of Parasitic Infections

The rising global incidence of parasitic infections, particularly in developing regions, highlights the need for effective treatment options. Pyrvinium Pamoate's efficacy in eliminating intestinal worms makes it a trusted choice among healthcare practitioners[1].

Expanding Healthcare Infrastructure

The expansion of healthcare infrastructure and improved access to pharmaceuticals in emerging markets are boosting demand for Pyrvinium Pamoate. Urbanization and rising disposable incomes in regions like Asia-Pacific are further contributing to market growth[1].

Regulatory Support and Research

Ongoing research into new therapeutic applications, including oncology, is enhancing the market potential of Pyrvinium Pamoate. Regulatory support for its use in various therapeutic areas encourages its adoption in clinical practice[1].

Mergers and Acquisitions

The market is witnessing a wave of mergers and acquisitions as companies seek to consolidate their market positions, expand their product portfolios, and leverage synergies to drive growth and competitiveness. These strategic consolidations provide access to new technologies, intellectual property, and talent, enabling companies to innovate faster and stay ahead of market trends[1].

Emerging Therapeutic Applications

Oncology

Pyrvinium Pamoate has shown promising results in the treatment of various cancers, including mesothelioma, pancreatic cancer, and breast cancer. Research by Dr. Antonio Giordano and his team has demonstrated that Pyrvinium Pamoate can impair the growth and migration of mesothelioma tumor cells by inhibiting a specific gene that encourages tumor cell proliferation[2].

Mechanisms of Action

The drug's efficacy against cancers is attributed to diverse mechanisms, including the inhibition of mitochondrial function, the WNT pathway, and cancer stem cell renewal. Studies have shown that Pyrvinium Pamoate can target aggressive breast cancer cells by inhibiting WNT signaling, which plays a key role in the self-renewal of tumor initiation cells (TICs)[3][5].

Clinical Trials

Ongoing clinical trials, such as the phase I open-label, single-arm, dose escalation trial for pancreatic cancer, are assessing the safety and tolerability of Pyrvinium Pamoate as an anti-cancer therapy. These trials highlight the potential for Pyrvinium Pamoate to be repurposed for cancer treatment, leveraging its existing FDA approval as an antihelminthic agent[4].

Regional Market Dynamics

Asia-Pacific

The Asia-Pacific region is a rapidly growing market for Pyrvinium Pamoate, driven by countries such as China, Japan, India, and South Korea. The region's large population, rising disposable income, and increasing urbanization are key factors contributing to the demand for Pyrvinium Pamoate products and services[1].

Latin America

Latin America presents both opportunities and challenges, with countries like Brazil, Mexico, and Argentina being key players. Economic fluctuations and political instability in some countries can impact market dynamics and consumer behavior[1].

Middle East and Africa

The Middle East and Africa represent emerging markets, with countries like UAE, Saudi Arabia, South Africa, and Nigeria showing promising growth potential. Economic diversification efforts, urbanization, and a young population are driving demand for Pyrvinium Pamoate products and services in the region[1].

Challenges and Opportunities

Competition and Regulatory Hurdles

Despite the growth prospects, the Pyrvinium Pamoate market faces challenges such as competition from other antihelminthic agents and regulatory hurdles. Economic factors, including fluctuations in global markets, can also impact the market's stability[1].

Demand for Sustainable Solutions

Growing environmental concerns and stringent regulations are fostering a shift towards sustainable alternatives, boosting the demand for eco-friendly Pyrvinium Pamoate products and services. This trend presents an opportunity for companies to innovate and offer more sustainable solutions[1].

Financial Trajectory

Revenue Projections

The projected growth from USD 19.33 Billion in 2024 to USD 35.06 Billion by 2031 indicates a robust financial trajectory for the Pyrvinium Pamoate market. This growth is supported by increasing demand, expanding therapeutic applications, and strategic consolidations in the industry[1].

Investment and Research

The ongoing research and clinical trials into new therapeutic applications of Pyrvinium Pamoate are attracting significant investment. This investment is crucial for the development of new treatments and the repurposing of the drug for cancer therapy, which in turn drives the market's financial growth[2][4].

Key Takeaways

  • The Pyrvinium Pamoate market is expected to grow significantly, driven by its effectiveness in treating parasitic infections and emerging applications in oncology.
  • The market is projected to reach USD 35.06 Billion by 2031, with a CAGR of 8.88% from 2024 to 2031.
  • Key drivers include increasing prevalence of parasitic infections, expanding healthcare infrastructure, and ongoing research into new therapeutic applications.
  • Regional markets, particularly in Asia-Pacific, Latin America, and the Middle East and Africa, are contributing to the growth.
  • Challenges such as competition and regulatory hurdles need to be addressed to sustain market growth.

FAQs

  1. What is the current market size and future growth prospects of the Pyrvinium Pamoate market?

    • The Pyrvinium Pamoate market is anticipated to grow from USD 19.33 Billion in 2024 to USD 35.06 Billion by 2031, with a CAGR of 8.88%[1].
  2. What are the key drivers of the Pyrvinium Pamoate market growth?

    • Key drivers include the increasing prevalence of parasitic infections, expanding healthcare infrastructure, regulatory support, and ongoing research into new therapeutic applications[1].
  3. What are the emerging therapeutic applications of Pyrvinium Pamoate?

    • Pyrvinium Pamoate is being researched for its potential in treating various cancers, including mesothelioma, pancreatic cancer, and breast cancer[2][3][4].
  4. What are the challenges facing the Pyrvinium Pamoate market?

    • Challenges include competition from other antihelminthic agents, regulatory hurdles, and economic factors such as market fluctuations[1].
  5. How is the regional market dynamics influencing the growth of Pyrvinium Pamoate?

    • Regions like Asia-Pacific, Latin America, and the Middle East and Africa are driving demand due to factors such as large populations, rising disposable incomes, and increasing urbanization[1].

Sources

  1. OpenPR: Pyrvinium Pamoate Market Size, Share and Forecast By Key Players-Dideu Group, Changzhou Yuanda Pharmaceutical Chemical, Hairui, Norna Group, Cayman[1].
  2. Asbestos.com: Parasite Drug Shows Effectiveness Against Mesothelioma[2].
  3. PubMed: Pyrvinium Pamoate: Past, Present, and Future as an Anti-Cancer Drug[3].
  4. BMJ Open: Repurposing the FDA-approved anthelmintic pyrvinium pamoate for pancreatic cancer[4].
  5. PLOS ONE: The Antihelmintic Drug Pyrvinium Pamoate Targets Aggressive Breast Cancer Cells[5].

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