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Last Updated: December 23, 2024

Sulfur - Generic Drug Details


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What are the generic sources for sulfur and what is the scope of freedom to operate?

Sulfur is the generic ingredient in two branded drugs marketed by Poythress and Bracco, and is included in two NDAs. There are three patents protecting this compound. Additional information is available in the individual branded drug profile pages.

There are two drug master file entries for sulfur.

Summary for sulfur
Recent Clinical Trials for sulfur

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
Societa Italiana di Chirurgia ColoRettaleN/A
Neopharmed Gentili S.p.A.N/A
OnLume Inc.Early Phase 1

See all sulfur clinical trials

US Patents and Regulatory Information for sulfur

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Bracco LUMASON sulfur hexafluoride lipid-type a microspheres FOR SUSPENSION;INTRAVENOUS 203684-001 Oct 15, 2014 RX Yes Yes ⤷  Subscribe ⤷  Subscribe Y ⤷  Subscribe
Bracco LUMASON sulfur hexafluoride lipid-type a microspheres FOR SUSPENSION;INTRAVENOUS 203684-001 Oct 15, 2014 RX Yes Yes ⤷  Subscribe ⤷  Subscribe Y ⤷  Subscribe
Poythress BENSULFOID sulfur POWDER;TOPICAL 002918-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Bracco LUMASON sulfur hexafluoride lipid-type a microspheres FOR SUSPENSION;INTRAVENOUS 203684-001 Oct 15, 2014 RX Yes Yes ⤷  Subscribe ⤷  Subscribe Y ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Sulfur Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory of Sulfa Drugs

Introduction

Sulfa drugs, also known as sulfonamides, have been a cornerstone in the treatment of various infectious diseases since their introduction in the 1930s. This article delves into the current market dynamics and financial trajectory of sulfa drugs, highlighting their growth drivers, challenges, and future prospects.

Historical Impact of Sulfa Drugs

Sulfa drugs were the first effective treatment for several often-fatal infectious diseases, including maternal mortality, pneumonia, and scarlet fever. Studies have shown that sulfa drugs led to a 25-40% decline in maternal mortality, a 17-36% decline in pneumonia mortality, and a 52-67% decline in scarlet fever mortality between 1937 and 1943[2].

Current Market Growth

The global sulfa drugs market is anticipated to grow at a rate of 4.80% from 2021 to 2028. This growth is driven by several key factors:

Increase in Infectious Diseases

The prevalence of various infections globally is a major driver for the sulfa drugs market. The rise in antibiotic-resistant infections due to the misuse or overuse of antibiotics has increased the demand for alternative treatments like sulfa drugs[1].

Chronic Diseases and Advanced Technologies

The surge in chronic diseases such as arthritis, asthma, and diabetes, along with the use of advanced technologies like high throughput, bioinformatics, and combinatorial chemistry, has further influenced the market. These technologies aid in the identification and development of better drug candidates[1].

Research and Development

Pharmaceutical companies are continuously investing in research and development to enhance the therapeutic activity of sulfonamides. This ongoing R&D is expected to introduce new and improved sulfa drugs, extending profitable opportunities for market players[1].

Regional Market Analysis

Asia-Pacific

The Asia-Pacific region dominates the sulfa drugs market due to the high consumption of antibiotics and the increasing prevalence of infectious diseases within the region. This region is expected to continue its dominance due to these factors[1].

North America

North America is projected to witness high growth during the forecast period, driven by the rising incidence of infectious diseases. The region's advanced healthcare infrastructure and significant investment in pharmaceutical research also contribute to this growth[1].

Challenges and Regulatory Hurdles

Despite the positive growth trajectory, the sulfa drugs market faces several challenges:

Stringent Regulations

The long approval process for drugs and stringent regulations are expected to obstruct market growth. These regulatory hurdles can delay the introduction of new sulfa drugs to the market[1].

Competition from Other Antibiotics

The development and widespread use of other antibiotics, such as penicillin, have somewhat overshadowed the importance of sulfa drugs. However, sulfa drugs remain crucial for treating certain antibiotic-resistant infections and specific diseases like urinary tract infections and leprosy[2].

Financial Trajectory

Market Size and Growth

The global sulfa drugs market is expected to grow significantly, driven by the factors mentioned above. The market's financial trajectory is positive, with a projected growth rate of 4.80% from 2021 to 2028[1].

Cost and Accessibility

Historically, sulfa drugs have been relatively inexpensive to produce and purchase. For example, in the 1930s, a full course of sulfa drugs cost approximately $35 to $100 per patient (in 2009 dollars), making them accessible to a wide population[2].

Future Prospects

New Drug Launches

The launch of new antibiotic drugs, including improved sulfa drugs, extends profitable opportunities for market players. These new drugs are expected to address the growing issue of antibiotic resistance and other infectious diseases[1].

Technological Advancements

The use of advanced technologies in drug development is expected to continue driving innovation in the sulfa drugs market. These technologies will help in identifying better drug candidates and enhancing the therapeutic activity of existing sulfa drugs[1].

Government Support and Healthcare Expenditure

Supportive government legislation and an increase in healthcare expenditure are also expected to positively impact the market. These factors will facilitate further research and development, as well as the adoption of new sulfa drugs[1].

Key Takeaways

  • The global sulfa drugs market is expected to grow at a rate of 4.80% from 2021 to 2028.
  • The market is driven by the prevalence of infectious diseases, chronic diseases, and advancements in pharmaceutical technologies.
  • Asia-Pacific and North America are key regions driving market growth.
  • Stringent regulations and competition from other antibiotics are significant challenges.
  • New drug launches and technological advancements are expected to drive future growth.
  • Government support and increased healthcare expenditure are positive factors for the market.

FAQs

What are the primary drivers of the sulfa drugs market?

The primary drivers include the prevalence of infectious diseases, the rise in antibiotic-resistant infections, and advancements in pharmaceutical technologies such as high throughput, bioinformatics, and combinatorial chemistry.

Which regions dominate the sulfa drugs market?

The Asia-Pacific region currently dominates the market due to high antibiotic consumption and the prevalence of infectious diseases. North America is also expected to witness significant growth.

What challenges does the sulfa drugs market face?

The market faces challenges such as stringent regulations, long drug approval processes, and competition from other antibiotics like penicillin.

How have sulfa drugs historically impacted public health?

Sulfa drugs led to significant declines in mortality rates for diseases like maternal mortality, pneumonia, and scarlet fever, and increased life expectancy by 0.4 to 0.8 years between 1937 and 1943[2].

What is the future outlook for the sulfa drugs market?

The future outlook is positive, with expected growth driven by new drug launches, technological advancements, and supportive government legislation and healthcare expenditure.

How affordable are sulfa drugs?

Historically, sulfa drugs have been relatively inexpensive to produce and purchase, making them accessible to a wide population[2].

Sources

  1. Data Bridge Market Research: Global Sulfa Drugs Market - Industry Trends and Forecast to 2028.
  2. NBER: Evidence on the Impact of Sulfa Drugs.
  3. Fortune Business Insights: Sulfur Market Size, Share, Report | Industry Forecast, 2024-2032.
  4. GlobeNewswire: Sulfur Chemicals Market Expands, Reaches US$5.06 Billion By 2030.
  5. NBER: The Cap-and-Trade Sulfur Dioxide Allowances Market Experiment.

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