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Last Updated: December 27, 2024

Details for Patent: 10,125,102


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Which drugs does patent 10,125,102 protect, and when does it expire?

Patent 10,125,102 protects ORLADEYO and is included in one NDA.

This patent has sixty patent family members in twenty-eight countries.

Summary for Patent: 10,125,102
Title:Human plasma kallikrein inhibitors
Abstract: Disclosed are compounds of formula I ##STR00001## as described herein, and pharmaceutically acceptable salts thereof. The compounds are inhibitors of plasma kallikrein. Also disclosed are pharmaceutical compositions comprising at least one such compound, and methods involving use of the compounds and compositions in the treatment and prevention of diseases and conditions characterized by unwanted plasma kallikrein activity.
Inventor(s): Kotian; Pravin L. (Birmingham, AL), Babu; Yarlagadda S. (Birmingham, AL), Wu; Minwan (Vestavia Hills, AL), Chintareddy; Venkat R. (Hoover, AL), Kumar; V. Satish (Birmingham, AL), Zhang; Weihe (Vestavia, AL)
Assignee: BioCryst Pharmaceuticals, Inc. (Durham, NC)
Application Number:15/123,059
Patent Claim Types:
see list of patent claims
Use; Composition; Compound;
Patent landscape, scope, and claims:

Understanding the Scope and Claims of a U.S. Patent: A Detailed Analysis of US10125171B2

Introduction to U.S. Patents

U.S. patents are legal documents that grant the inventor or assignee the exclusive right to make, use, and sell an invention for a specified period. To understand the scope and claims of a specific patent, such as US10125171B2, it is crucial to delve into the various sections and components of the patent document.

Structure of a U.S. Patent Document

A U.S. patent document is divided into several key sections, each providing specific information about the invention.

Document Number and Type

  • The document number, prefixed with "US," indicates it is a U.S. patent. The "B2" code signifies that this patent has a previously published application[1].

Title and Abstract

  • The title provides a brief description of the invention, limited to 500 characters or less. The abstract is a non-technical summary of the invention, giving a general overview of what the patent covers[1].

Field of the Invention

  • This section describes the technical field to which the invention pertains. For US10125171B2, the field involves cell-reactive compstatin analogs and their uses[5].

Background of the Invention

  • This section discusses the prior art and the problems that the invention aims to solve. It sets the context for why the invention is necessary and how it improves upon existing solutions[1].

Summary of the Invention

  • A concise summary of the invention, highlighting its key features and how it addresses the problems identified in the background section.

Detailed Description of the Invention

  • This is the specification section, which includes a detailed written description of the invention. It must be sufficient for someone of ordinary skill in the same technical field to understand and replicate the invention. This section often includes descriptions of the drawings and how the invention works[1].

Drawings and Figures

  • The drawings section contains black and white illustrations that depict the technical details of the invention. These drawings are crucial for understanding the physical and functional aspects of the invention[1].

Claims

  • The claims section is perhaps the most critical part of the patent document, as it defines the scope of protection for the invention. Claims are numbered paragraphs that outline what the inventor considers to be the novel and non-obvious aspects of the invention. The phrases “I claim” or “What is claimed” precede the numbered claims[1].

Types of Claims

  • Independent Claims: These are standalone claims that define the invention without referencing other claims. They are typically broader and more comprehensive.
  • Dependent Claims: These claims build upon independent claims and are narrower, often specifying additional features or limitations.

Claim Analysis for US10125171B2

For the patent US10125171B2, the claims would define the specific cell-reactive compstatin analogs, their compositions, and their uses. Here is an example of how a claim might be structured:

  • Claim 1: "A cell-reactive compstatin analog, comprising: a compstatin moiety; and a targeting moiety adapted to bind to a specific cell type; wherein the compstatin analog is effective in inhibiting complement activation."

This claim defines the core components of the invention and sets the legal boundaries for what is protected under the patent.

Patent Scope and Metrics

Independent Claim Length and Count

Research has shown that the scope of a patent can be measured using metrics such as independent claim length and independent claim count. Narrower claims, as indicated by shorter lengths and fewer counts, are often associated with a higher probability of grant and a shorter examination process[3].

Breadth of Patent Classes

The breadth of patent classes can also indicate the scope of the patent. Patents that span multiple classes may have a broader scope, while those confined to a single class may be narrower.

Prior Art and References

Citations and References

The references section lists U.S. and foreign patent documents, as well as other publications, cited as related prior art by the inventor and the patent examiner. This section helps in understanding the existing landscape and how the current invention differs from or builds upon previous work[1].

Assignee, Inventors, and Patent Attorney

Ownership and Inventorship

The assignee is the owner of the patent at the time it was issued, which can be a person, company, or organization. The inventors are listed separately, and their contributions to the invention are acknowledged. The patent attorney or firm that assisted in the application process is also identified[1].

Examination Process and Term Adjustment

Examination and Grant

The patent goes through a rigorous examination process before it is granted. The primary examiner reviews the application to ensure it meets the criteria for novelty, non-obviousness, and utility. Any delays in the process can result in term adjustments to extend the patent's validity period[1].

Maintenance and Expiration

Maintenance Fees

To keep the patent in force, maintenance fees must be paid at specified intervals. Failure to pay these fees can result in the patent expiring prematurely[4].

Expiration Date

The patent expires after a specified term, typically 20 years from the earliest filing date of the application. The exact expiration date can be calculated using tools provided by the USPTO[4].

Patent Landscape and Search Tools

USPTO Resources

The USPTO website offers extensive resources for searching patents, including full-text and image searches for patents from 1976 onwards. For older patents, images and classification numbers are available[2].

Other Search Tools

Other resources like Google Patents, Espacenet, and various library guides provide additional avenues for searching and analyzing patents[2].

Key Takeaways

  • Understanding Claims: The claims section is crucial for defining the scope of protection for the invention.
  • Patent Scope Metrics: Metrics like independent claim length and count can help in assessing the breadth and validity of the patent.
  • Prior Art: Understanding the prior art cited in the patent helps in contextualizing the invention within the existing landscape.
  • Maintenance: Regular maintenance fees are necessary to keep the patent in force.
  • Search Tools: Utilizing various search tools and resources can aid in comprehensive patent analysis.

Frequently Asked Questions (FAQs)

1. What is the purpose of the claims section in a U.S. patent?

The claims section defines the legal boundaries of the invention, specifying what is protected under the patent.

2. How can the scope of a patent be measured?

The scope can be measured using metrics such as independent claim length and independent claim count, as well as the breadth of patent classes.

3. What is the significance of prior art in a patent document?

Prior art helps in understanding the existing landscape and how the current invention differs from or builds upon previous work.

4. Why are maintenance fees important for a patent?

Maintenance fees are necessary to keep the patent in force and prevent it from expiring prematurely.

5. Where can I find full-text and image searches for U.S. patents?

Full-text and image searches for U.S. patents can be found on the USPTO website, Google Patents, and other resources like Espacenet.

Cited Sources:

  1. Guides.library.queensu.ca: How to Read a U.S. Patent - Patents and Designs - Research Guides.
  2. Libguides.nypl.org: How to Search for an Historical U.S. Patent - NYPL Libguides.
  3. SSRN.com: Patent Claims and Patent Scope.
  4. USPTO.gov: Patents - USPTO.
  5. Patents.google.com: US10125171B2 - Cell-reactive, long-acting, or targeted compstatin analogs and uses thereof.

More… ↓

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Drugs Protected by US Patent 10,125,102

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Biocryst ORLADEYO berotralstat hydrochloride CAPSULE;ORAL 214094-001 Dec 3, 2020 RX Yes No 10,125,102 ⤷  Subscribe Y PROPHYLAXIS TO PREVENT ATTACKS OF HEREDITARY ANGIOEDEMA (HAE) IN ADULTS AND PEDIATRIC PATIENTS 12 YEARS OF AGE AND OLDER ⤷  Subscribe
Biocryst ORLADEYO berotralstat hydrochloride CAPSULE;ORAL 214094-002 Dec 3, 2020 RX Yes Yes 10,125,102 ⤷  Subscribe Y PROPHYLAXIS TO PREVENT ATTACKS OF HEREDITARY ANGIOEDEMA (HAE) IN ADULTS AND PEDIATRIC PATIENTS 12 YEARS OF AGE AND OLDER ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 10,125,102

PCT Information
PCT FiledMarch 09, 2015PCT Application Number:PCT/US2015/019535
PCT Publication Date:September 11, 2015PCT Publication Number: WO2015/134998

International Family Members for US Patent 10,125,102

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 3113772 ⤷  Subscribe 301142 Netherlands ⤷  Subscribe
European Patent Office 3113772 ⤷  Subscribe CA 2021 00040 Denmark ⤷  Subscribe
European Patent Office 3113772 ⤷  Subscribe PA2021524 Lithuania ⤷  Subscribe
European Patent Office 3113772 ⤷  Subscribe LUC00233 Luxembourg ⤷  Subscribe
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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