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Last Updated: December 22, 2024

Details for Patent: 10,273,477


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Summary for Patent: 10,273,477
Title:Therapeutic compositions
Abstract: This application relates to therapeutic siRNA agents and methods of making and using the agents.
Inventor(s): Manoharan; Muthiah (Cambridge, MA), Rajeev; Kallanthottathil G. (Cambridge, MA), Bumcrot; David (Cambridge, MA)
Assignee: Alnylam Pharmaceuticals, Inc. (Cambridge, MA)
Application Number:15/623,139
Patent Claim Types:
see list of patent claims
Use;
Patent landscape, scope, and claims:

Understanding the Scope and Claims of United States Patent 10,273,477

Introduction

Patents are crucial for protecting intellectual property and driving innovation. The United States Patent 10,273,477, titled "Therapeutic compositions," is an example of a patent that covers significant ground in the field of therapeutic siRNA agents. Here, we will delve into the details of this patent, analyzing its scope, claims, and the broader patent landscape it operates within.

Patent Overview

Title and Abstract The patent 10,273,477 pertains to "Therapeutic compositions" and involves therapeutic siRNA (small interfering RNA) agents. The abstract outlines methods of making and using these agents, highlighting their potential therapeutic applications[2].

Scope of the Patent

Patent Scope Metrics

The scope of a patent is often measured using metrics such as independent claim length (ICL) and independent claim count (ICC). These metrics help in understanding the breadth and clarity of the patent claims. Narrower claims, as indicated by shorter ICL and lower ICC, are generally associated with a higher probability of grant and a shorter examination process[3].

Claim Language and Clarity

The clarity and specificity of claim language are critical for determining the patent's scope. Broad or unclear claims can lead to disputes and litigation, while narrower, well-defined claims provide clearer boundaries for what is protected. In the case of patent 10,273,477, the claims would need to be scrutinized for their clarity and specificity to understand the exact scope of protection.

Claims Analysis

Independent Claims

Independent claims in a patent define the broadest scope of protection. For patent 10,273,477, these claims would outline the core therapeutic siRNA agents and methods of their use. Analyzing these claims involves looking at the number of words used (ICL) and the total number of independent claims (ICC), which can provide insights into the patent's breadth and complexity[3].

Dependent Claims

Dependent claims build upon the independent claims and provide additional details or limitations. These claims help in narrowing down the scope and ensuring that the patent covers specific aspects of the invention without being overly broad.

Patent Landscape

Industry Context

The patent landscape for therapeutic siRNA agents is highly competitive and rapidly evolving. Companies and research institutions are continually developing new siRNA therapies, which makes the protection offered by patents like 10,273,477 crucial for maintaining a competitive edge.

Expiring Patents

The expiration of related patents can significantly impact the landscape. For instance, the expiration of drug patents between 2020 and 2022, as listed in other sources, can open up new opportunities for generic or biosimilar products, but it also highlights the need for continuous innovation and patent protection in the field[4].

Valuation and Market Impact

Patent Valuation Methods

The value of a patent like 10,273,477 can be determined using the cost, income, and market approaches. The cost approach considers the development costs, the income approach looks at future benefits, and the market approach compares it to similar patents sold in the market. For example, significant patent deals in the tech and pharmaceutical sectors have shown that patents can be highly valuable, with prices ranging from hundreds of thousands to millions of dollars per patent[1].

Market Transactions

Recent market transactions involving patent portfolios can provide benchmarks for valuing patent 10,273,477. For instance, the sale of Nortel's patent portfolio for $4.5 billion or Google's acquisition of Motorola Mobility's patents for $12.5 billion, including 24,500 patents, demonstrate the high value placed on intellectual property in strategic industries[1].

Litigation and Patent Quality

Patent Quality Concerns

The quality of patent claims, including their breadth and clarity, is a significant concern. Broad or unclear claims can lead to increased litigation and licensing costs, which can diminish incentives for innovation. The examination process at the USPTO tends to narrow the scope of patent claims, ensuring that only valid and clear claims are granted[3].

Litigation Implications

Patents with clearer and narrower claims are less likely to be involved in lengthy and complex litigation. This is crucial for maintaining the integrity of the patent system and ensuring that patents like 10,273,477 contribute positively to innovation rather than hindering it.

Conclusion

Understanding the scope and claims of United States Patent 10,273,477 involves a detailed analysis of its claim language, the metrics used to measure patent scope, and the broader patent landscape. Here are the key takeaways:

  • Patent Scope: Measured using independent claim length and independent claim count, which indicate the breadth and clarity of the patent.
  • Claims Analysis: Independent and dependent claims define the scope of protection, with narrower claims generally preferred for clarity and validity.
  • Patent Landscape: The competitive and evolving nature of therapeutic siRNA agents makes patent protection crucial.
  • Valuation: Determined using cost, income, and market approaches, with significant market transactions providing benchmarks.
  • Litigation and Quality: Clear and narrow claims are essential for avoiding litigation and ensuring the patent contributes positively to innovation.

Key Takeaways

  • Scope Metrics: Independent claim length and count are key metrics for understanding patent scope.
  • Claims Clarity: Clear and specific claims are crucial for avoiding disputes and ensuring patent validity.
  • Market Impact: Patents can be highly valuable, with significant market transactions setting benchmarks.
  • Litigation: Clear claims reduce the likelihood of lengthy and complex litigation.
  • Innovation: Well-defined patents contribute positively to innovation by providing clear boundaries for protection.

FAQs

  1. What is the main subject of United States Patent 10,273,477?

    • The main subject is therapeutic siRNA agents and methods of making and using these agents.
  2. How is the scope of a patent typically measured?

    • The scope is typically measured using metrics such as independent claim length (ICL) and independent claim count (ICC).
  3. Why are clear and narrow claims important in a patent?

    • Clear and narrow claims are important because they reduce the likelihood of disputes and litigation, ensuring the patent's validity and contributing positively to innovation.
  4. What are the common methods for valuing a patent?

    • The common methods include the cost approach, income approach, and market approach.
  5. How do expiring patents impact the patent landscape?

    • Expiring patents can open up new opportunities for generic or biosimilar products and highlight the need for continuous innovation and patent protection in the field.

Sources

  1. The Value of a Patent - Perpetual Motion Patents
  2. Drugs covered by patent 10,273,477 - DrugPatentWatch
  3. Patent Claims and Patent Scope - Hoover Institution
  4. List - 91 Drug Patents that are Expiring between 2020 to 2022 - GreyB
  5. Stabilized polynucleotides for use in RNA interference - PubChem

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Drugs Protected by US Patent 10,273,477

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Alnylam Pharms Inc GIVLAARI givosiran sodium SOLUTION;SUBCUTANEOUS 212194-001 Nov 20, 2019 RX Yes Yes 10,273,477 ⤷  Subscribe Y ⤷  Subscribe
Novartis LEQVIO inclisiran sodium SOLUTION;SUBCUTANEOUS 214012-001 Dec 22, 2021 RX Yes Yes 10,273,477 ⤷  Subscribe Y ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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