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Last Updated: December 21, 2024

Details for Patent: 10,383,876


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Which drugs does patent 10,383,876 protect, and when does it expire?

Patent 10,383,876 protects ALIQOPA and is included in one NDA.

This patent has fifty-three patent family members in forty-two countries.

Summary for Patent: 10,383,876
Title:Substituted 2,3-dihydroimidazo[1,2-c]quinazoline salts
Abstract: The present invention relates:--to 2-amino-N-[7-methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo-[1,2-- c]quinazolin-5-yl]pyrimidine-5-carboxamide dihydrochloride salt of formula (II): or a tautomer, solvate or hydrate thereof;--to methods of preparing said dihydrochloride salt;--to said dihydrochloride salt for the treatment and/or prophylaxis of a disease;--to the use of said dihydrochloride salt for the preparation of a medicament for the treatment and/or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, more particularly for the treatment or prophylaxis of a cancer, particularly lung cancer, in particular non-small cell lung carcinoma, colorectal cancer, melanoma, pancreatic cancer, hepatocyte carcinoma, pancreatic cancer, hepatocyte carcinoma or breast cancer;--to a pharmaceutical composition comprising said dihydrochloride salt; and--to a pharmaceutical combination comprising said dihydrochloride salt in combination with one or more further pharmaceutical agents. ##STR00001##
Inventor(s): Peters; Jan-Georg (Solingen, DE), Militzer; Hans-Christian (Odenthal, DE), Muller; Hartwig (Velbert, DE)
Assignee: BAYER INTELLECTUAL PROPERTY GMBH (Monheim, DE)
Application Number:14/009,599
Patent Claim Types:
see list of patent claims
Use; Composition; Formulation; Compound; Delivery;
Patent landscape, scope, and claims:

United States Patent 10,383,876: A Detailed Analysis of Scope, Claims, and Patent Landscape

Introduction

United States Patent 10,383,876, titled "Substituted 2,3-dihydroimidazo[1,2-c]quinazoline salts," is a patent that covers a specific class of chemical compounds. This analysis will delve into the scope, claims, and the broader patent landscape surrounding this patent.

Patent Overview

Patent Title and Abstract

The patent, issued on August 20, 2019, pertains to substituted 2,3-dihydroimidazo[1,2-c]quinazoline salts. These compounds are of interest in pharmaceutical research due to their potential therapeutic properties.

Inventors and Assignees

The patent lists the inventors and the assignees, which are crucial for understanding the ownership and the potential commercial applications of the patented compounds[2].

Scope of the Patent

Definition of Scope

The scope of a patent is defined by its claims, which outline the boundaries of what is protected under the patent. The scope is a critical aspect as it determines the extent of protection and the potential for infringement[3].

Claim Analysis

  • Independent Claims: The patent includes several independent claims that define the core inventions. These claims are typically broader and more general, setting the foundation for the dependent claims.
  • Dependent Claims: Dependent claims are narrower and build upon the independent claims. They often specify particular aspects or variations of the invention.
  • Claim Length and Count: Research suggests that the length and count of independent claims can be metrics for measuring patent scope. Patents with narrower claims at publication tend to have a higher probability of grant and a shorter examination process[3].

Claims in US 10,383,876

The patent includes multiple claims that describe the chemical structure and synthesis of the substituted 2,3-dihydroimidazo[1,2-c]quinazoline salts. These claims are detailed and specific, ensuring that the protection is clear and enforceable.

Claims and Patent Quality

Metrics for Patent Quality

The quality of a patent is often debated, with metrics such as claim length and count being used to assess the breadth and clarity of the claims. Narrower claims are generally associated with higher patent quality, as they are more specific and less likely to be overly broad or vague[3].

Application to US 10,383,876

In the case of US 10,383,876, the claims are detailed and specific, indicating a higher quality patent. This specificity helps in reducing the likelihood of disputes over patent scope and validity.

Patent Landscape

Global Patent Search

To understand the broader patent landscape, it is essential to conduct a global patent search. Resources such as the USPTO's Patent Public Search, the European Patent Office's esp@cenet, and the World Intellectual Property Organization's PATENTSCOPE provide comprehensive databases for searching patents globally[1][4].

Related Patents and Applications

  • Patent Family: Using tools like the Global Dossier, one can identify the patent family for US 10,383,876, including related applications filed at participating IP Offices. This helps in understanding the global protection and any ongoing examination processes[1].
  • Citation Data: The Common Citation Document (CCD) application consolidates prior art cited by multiple offices, providing a single point of access to citation data. This is useful for identifying prior art and understanding the novelty of the invention[1].

Pharmaceutical Implications

Drug Coverage

The patented compounds are of interest in the pharmaceutical industry. The patent covers specific salts of substituted 2,3-dihydroimidazo[1,2-c]quinazoline, which may have therapeutic applications. Understanding the expiration dates and potential generic entry is crucial for pharmaceutical companies[5].

Expiration and Generic Entry

The patent expiration date and the potential for generic entry are critical for pharmaceutical companies planning to develop or market these compounds. This information helps in strategizing product development and market entry[5].

Legal and Regulatory Aspects

Patent Assignment and Ownership

Changes in ownership or assignments of the patent can be tracked using the Patent Assignment Search tool. This is important for understanding the current legal status and any potential licensing or litigation issues[1].

Office Actions and Examination Data

The Patent Examination Data System (PEDS) provides access to bibliographic data and office actions related to the patent. This information is valuable for understanding the examination process and any challenges faced during the patent grant[1].

Conclusion

Understanding the scope, claims, and patent landscape of US 10,383,876 is essential for anyone involved in the development or commercialization of the patented compounds. Here are some key takeaways:

  • Specific Claims: The patent includes detailed and specific claims, which are indicative of higher patent quality.
  • Global Protection: The patent is part of a global patent family, with related applications and citations available through various international databases.
  • Pharmaceutical Implications: The patented compounds have potential therapeutic applications, and understanding the patent expiration and generic entry is crucial for pharmaceutical companies.
  • Legal and Regulatory Compliance: Tracking changes in ownership and office actions is important for legal and regulatory compliance.

FAQs

Q: How can I search for related patents globally?

A: You can use resources like the USPTO's Patent Public Search, the European Patent Office's esp@cenet, and the World Intellectual Property Organization's PATENTSCOPE to search for related patents globally[1][4].

Q: What is the significance of claim length and count in patent scope?

A: Claim length and count are metrics used to measure patent scope. Narrower claims are associated with higher patent quality and a higher probability of grant[3].

Q: How can I find the patent family for a specific application?

A: You can use the Global Dossier service to identify the patent family for a specific application, including related applications filed at participating IP Offices[1].

Q: What is the Common Citation Document (CCD) application?

A: The CCD application consolidates prior art cited by multiple offices, providing a single point of access to citation data for the family members of a patent application[1].

Q: Where can I find information on patent assignments and changes in ownership?

A: You can use the Patent Assignment Search tool to search for patent assignments and changes in ownership[1].

Sources

  1. USPTO: Search for patents - USPTO.
  2. PubChem: Substituted 2,3-dihydroimidazo[1,2-c]quinazoline salts - Patent US-10383876-B2.
  3. SSRN: Patent Claims and Patent Scope.
  4. Duke University Libraries: Finding Patents Online - Research Guides.
  5. DrugPatentWatch: Pharmaceutical drugs covered by patent 10,383,876.

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Drugs Protected by US Patent 10,383,876

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Bayer Healthcare ALIQOPA copanlisib dihydrochloride POWDER;INTRAVENOUS 209936-001 Sep 14, 2017 DISCN Yes No 10,383,876 ⤷  Subscribe Y Y ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 10,383,876

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
11161111Apr 5, 2011
PCT Information
PCT FiledMarch 29, 2012PCT Application Number:PCT/EP2012/055600
PCT Publication Date:October 11, 2012PCT Publication Number: WO2012/136553

International Family Members for US Patent 10,383,876

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
African Regional IP Organization (ARIPO) 3709 ⤷  Subscribe
Argentina 085718 ⤷  Subscribe
Australia 2012238891 ⤷  Subscribe
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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