Details for Patent: 10,653,710

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Which drugs does patent 10,653,710 protect, and when does it expire?

Patent 10,653,710 protects TIBSOVO and is included in one NDA.

This patent has thirty-three patent family members in twenty-eight countries.

Summary for Patent: 10,653,710

Title:	Combination therapy for treating malignancies
Abstract:	Provided are methods and compositions for treating hematological malignancies in patients carrying an IDH1 mutation using a combination of an inhibitor of mutant IDH1 enzyme, (S)-N-((S)-1-(2-chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethy- l)-1-(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-car- boxamide, or a pharmaceutically acceptable salt thereof (COMPOUND 2) and a DNA demethylating agent.
Inventor(s):	Agresta; Samuel V. (Lexington, MA), Viswanadhan; Krishnan (East Hanover, NJ), DiMartino; Jorge (Belmont, CA), Chopra; Vivek Saroj Kumar (South San Francisco, CA), MacBeth; Kyle J. (San Francisco, CA), Knight; Robert Douglas (Berkeley Heights, NJ), Kenvin; Laurie (New Hope, PA), Xu; Qiang (Bernards, NJ)
Assignee:	Agios Pharmaceuticals, Inc. (Cambridge, MA) Celgene Corporation (Summit, NJ)
Application Number:	15/767,822
Patent Claim Types: see list of patent claims	Use; Composition;

Drugs Protected by US Patent 10,653,710

Glossary

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
Servier	TIBSOVO	ivosidenib	TABLET;ORAL	211192-001	Jul 20, 2018		RX	Yes	Yes	⤷ Sign Up	⤷ Sign Up				A METHOD FOR TREATING NEWLY DIAGNOSED AML CHARACTERIZED BY THE PRESENCE OF A MUTANT ALLELE OF IDH1 SELECTED FROM R132H, R132C, R132L, R132V, R132S AND R132GF BY ADMINISTERING IVOSIDENIB AND AZACITIDINE	⤷ Sign Up
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

Foreign Priority and PCT Information for Patent: 10,653,710

PCT Information
PCT Filed	October 14, 2016	PCT Application Number:	PCT/US2016/057042
PCT Publication Date:	April 20, 2017	PCT Publication Number:	WO2017/066571

International Family Members for US Patent 10,653,710

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Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Australia	2016338557	⤷ Sign Up
Brazil	112018007656	⤷ Sign Up
Brazil	122024000250	⤷ Sign Up
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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