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Last Updated: December 22, 2024

Details for Patent: 10,772,888


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Summary for Patent: 10,772,888
Patent landscape, scope, and claims:
Title:Solid pharmaceutical compositions containing an integrase inhibitor
Abstract: Compressed tablets for oral administration containing raltegravir in the form of a pharmaceutically acceptable salt are described. The tablets comprise: (A) an intragranular component comprising (i) an effective amount of an alkali metal salt of raltegravir, (ii) optionally a first superdisintegrant, and (iii) a binder; and (B) an extragranular component comprising (i) a second superdisintegrant, (ii) a filler, and (iii) a lubricant. Methods for preparing the tablets and the use of the tablets, optionally in combination with other anti-HIV agents, for the inhibition of HIV integrase, for the treatment or prophylaxis of HIV infection, or for the treatment, delay in the onset, or prophylaxis of AIDS are also described.
Inventor(s): Mahjour; Majid (Schwenksville, PA), Li; Feng (Dresher, PA), Ma; Decheng (Souderton, PA), Sotthivirat; Sutthilug (Lansdale, PA)
Assignee: Merck Sharp & Dohme Corp. (Rahway, NJ)
Application Number:15/483,030
Patent Claim Types:
see list of patent claims
Use; Composition; Dosage form;

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Drugs Protected by US Patent 10,772,888

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Msd Sub Merck ISENTRESS HD raltegravir potassium TABLET;ORAL 022145-002 May 26, 2017 RX Yes Yes 10,772,888 ⤷  Subscribe TREATMENT OF HIV-1 INFECTION ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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