Details for Patent: 12,048,695

Which drugs does patent 12,048,695 protect, and when does it expire?

Patent 12,048,695 protects LYNPARZA and is included in one NDA.

This patent has fifty-two patent family members in forty-two countries.

Summary for Patent: 12,048,695

Title:	Immediate release pharmaceutical formulation of 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one
Abstract:	The present invention relates to a pharmaceutical formulation comprising the drug 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one in a solid dispersion with a matrix polymer that exhibits low hygroscopicity and high softening temperature, such as copovidone. The invention also relates to a daily pharmaceutical dose of the drug provided by such a formulation. In addition, the invention relates to the use of a matrix polymer that exhibits low hygroscopicity and high softening temperature in solid dispersion with 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one for increasing the bioavailability of the drug.
Inventor(s):	Michael Karl Bechtold, Julie Kay Cahill, Katja Maren Fastnacht, Kieran James Lennon, Bernd Harald Liepold, Claudia Bettina Packhaeuser, Benedikt Steitz
Assignee:	Abbott GmbH and Co KG, Kudos Pharmaceuticals Ltd
Application Number:	US18/312,375
Patent Claim Types: see list of patent claims

Detailed Analysis of the Scope and Claims of United States Patent 12,048,695

Introduction

United States Patent 12,048,695, while not explicitly detailed in the provided sources, can be analyzed through a comprehensive approach that includes understanding the patent's claims, the broader patent landscape, and the relevant legal and technical contexts.

Understanding the Patent Claims

To analyze the scope and claims of a patent, it is crucial to review the patent document itself. Here are the key steps:

Claim Construction

• The claims section of the patent defines the scope of the invention. Each claim must be carefully analyzed to understand what is protected and what is not. Claims can be independent or dependent, with dependent claims building upon the independent claims[4].

Claim Types

• Independent Claims: These stand alone and define the invention without reference to other claims.
• Dependent Claims: These refer back to and further limit the independent claims.

Patent Landscape Analysis

A patent landscape analysis is essential to understand the position of the patent within the broader technological and competitive landscape.

What is a Patent Landscape Analysis?

• This analysis involves reviewing, organizing, and extracting value from extensive patent search results in a specific technology area. It helps in identifying key players, technologies, and trends[3].

Steps in Patent Landscape Analysis

1. Define the Scope: Identify the specific technology area and relevant keywords.
2. Conduct Patent Searches: Use databases and software to search for patents related to the defined scope.
3. Filter and Categorize: Narrow down the search results based on relevance and categorize them by technology, organization, or other criteria.
4. Analyze the Results: Extract technical, legal, and business information from the patents.
5. Visualize the Data: Use mapping and analytics tools to visualize the patent landscape.

Technical and Legal Context

Patentability Requirements

• To be patentable, an invention must be useful, novel, and nonobvious, and claim patentable subject matter. The USPTO examiner considers these requirements during the patent application process[4].

Prior Art and Novelty

• The invention must not be fully anticipated by prior patents, publications, or other state of the art knowledge. This ensures that the invention is novel and not obvious to a competent artisan at the time of its creation[4].

Specifics of Patent 12,048,695

Given the lack of direct information on this specific patent, here is a general approach to analyzing its scope and claims:

Classification and Prior Art

• Check the classification codes (e.g., A61K 47/12) to understand the technological area the patent belongs to. This can help in identifying prior art and similar patents[5].

Claims and Description

• Review the claims and the detailed description of the invention to understand its technical aspects and how it differs from prior art.

Inventors and Assignees

• Identify the inventors and assignees to understand the organizational context and potential collaborations or competitors.

Impact on the Market and Competitors

Competitive Analysis

• A patent landscape analysis can reveal which organizations are actively innovating in the same area. This helps in understanding the competitive landscape and potential threats or opportunities.

Innovation Trends

• Analyze how technical problems are being solved and which product features are disclosed in the patent and related patents. This can provide insights into innovation trends and future directions in the field[3].

Legal Considerations

Patent Term Adjustments and Extensions

• Understand how patent term adjustments (PTA) and extensions (PTE) might affect the patent's term. For instance, PTA can extend the patent term due to delays in the USPTO's processing, while PTE can extend the term due to regulatory review periods[1].

Double Patenting Issues

• Ensure that the patent does not face issues related to double patenting, where an inventor might secure multiple patents for the same invention, potentially extending the patent term unjustly[1].

Key Takeaways

• Patent Claims: Carefully review the claims to understand the scope of protection.
• Patent Landscape: Conduct a thorough analysis to position the patent within the broader technological and competitive landscape.
• Technical and Legal Context: Ensure the patent meets all patentability requirements and is not anticipated by prior art.
• Market Impact: Analyze the competitive landscape and innovation trends to understand the patent's significance and potential impact.

Frequently Asked Questions

1. What is the purpose of a patent landscape analysis?

   • A patent landscape analysis helps in understanding innovation activity, identifying key players, and extracting technical, legal, and business information from patent data.

2. How do you determine the novelty of an invention?

   • An invention is novel if it is not fully anticipated by prior patents, publications, or other state of the art knowledge.

3. What are the different types of patent claims?

   • There are independent claims and dependent claims. Independent claims stand alone, while dependent claims further limit the independent claims.

4. How do patent term adjustments (PTA) and extensions (PTE) affect a patent?

   • PTA can extend the patent term due to delays in the USPTO's processing, while PTE can extend the term due to regulatory review periods.

5. Why is it important to check for double patenting issues?

   • Double patenting issues can arise if an inventor secures multiple patents for the same invention, potentially extending the patent term unjustly.

Cited Sources

1. In re Cellect - United States Court of Appeals for the Federal Circuit
2. Provisur - United States Court of Appeals for the Federal Circuit
3. How to perform a patent landscape analysis in 5 key steps - IP Checkups
4. Patents and Innovation Policy - CRS Reports
5. Official Gazette for Patents - USPTO

Drugs Protected by US Patent 12,048,695

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
Astrazeneca	LYNPARZA	olaparib	TABLET;ORAL	208558-001	Aug 17, 2017		RX	Yes	No			Y
Astrazeneca	LYNPARZA	olaparib	TABLET;ORAL	208558-002	Aug 17, 2017		RX	Yes	Yes			Y

International Family Members for US Patent 12,048,695

Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
European Patent Office	2346495		300956	Netherlands
European Patent Office	2346495		122018000124	Germany
European Patent Office	2346495		CA 2018 00039	Denmark