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Last Updated: December 23, 2024

Details for Patent: 4,731,478


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Summary for Patent: 4,731,478
Title: Sulfamoyl-substituted phenethylamine derivatives, their preparation, and pharmaceutical compositions, containing them
Abstract:A novel process is provided for the preparation of optical isomers of certain sulfamoyl-substituted phenethylamine derivatives which exhibit .alpha.-adrenergic blocking agents which can be used for various treatments such as for the treatment of congestive heart failure.
Inventor(s): Niigata; Kunihiro (Saitama, JP), Fujikura; Takashi (Saitama, JP)
Assignee: Yamanouchi Pharmaceutical Co., Ltd. (Tokyo, JP)
Application Number:06/803,204
Patent Claim Types:
see list of patent claims
Compound; Composition;
Patent landscape, scope, and claims:

United States Patent 4,731,478: A Detailed Analysis of Scope, Claims, and Patent Landscape

Introduction

United States Patent 4,731,478, titled "Sulfamoyl-substituted phenethylamine derivatives, their preparation and pharmaceutical compositions," is a patent that has significant implications in the field of pharmaceuticals. This analysis will delve into the scope and claims of the patent, as well as the broader patent landscape in which it resides.

Background and Invention

The patent, granted on March 22, 1988, describes a class of sulfamoyl-substituted phenethylamine derivatives. These compounds are of interest due to their potential therapeutic applications, particularly in the treatment of various medical conditions[2].

Scope of the Patent

The scope of the patent encompasses the synthesis, preparation, and pharmaceutical compositions of the sulfamoyl-substituted phenethylamine derivatives. Here are the key aspects:

Chemical Structure

The patent details the chemical structure of these derivatives, which includes the sulfamoyl group attached to the phenethylamine backbone. This specific modification is crucial for the compounds' therapeutic properties.

Synthesis Methods

The patent describes various methods for synthesizing these compounds, including the starting materials, reaction conditions, and purification techniques. This information is vital for anyone looking to replicate or modify these compounds.

Pharmaceutical Compositions

The patent also covers the formulation of pharmaceutical compositions containing these derivatives. This includes details on dosage forms, excipients, and other components necessary for therapeutic use.

Claims of the Patent

The claims of the patent are the legal boundaries that define what is protected under the patent. Here are some key claims:

Compound Claims

The patent claims the sulfamoyl-substituted phenethylamine derivatives themselves, specifying the exact chemical structures and their therapeutic uses.

Method Claims

Claims are also made for the methods of synthesizing these compounds, ensuring that any identical or very similar synthesis processes would infringe on the patent.

Composition Claims

The patent claims pharmaceutical compositions that include these derivatives, covering various dosage forms and formulations.

Patent Landscape Analysis

A patent landscape analysis provides a comprehensive view of the intellectual property landscape surrounding a particular technology or invention. Here’s how it applies to U.S. Patent 4,731,478:

Prior Art and Related Patents

To understand the novelty and non-obviousness of the patented compounds, a thorough search of prior art and related patents is necessary. This involves using tools like the USPTO's Patent Public Search, Global Dossier, and other international patent databases to identify similar or overlapping patents[4].

Competitor Analysis

Identifying key competitors in the field involves analyzing the patent portfolios of other companies working on similar compounds. This can reveal market leaders and potential collaborators or competitors[3].

Technology Saturation

A patent landscape analysis can also indicate the level of technology saturation in the field. If there are numerous patents related to sulfamoyl-substituted phenethylamine derivatives, it may suggest a mature technology area where innovation might be more challenging[3].

Geographical Distribution

Understanding the geographical distribution of related patents can help in identifying global market trends and regulatory environments. For example, patents filed in different regions may indicate varying levels of interest and regulatory approval processes[4].

Strategic Insights

A comprehensive patent landscape analysis provides strategic insights that can guide business and R&D decisions:

Innovation Areas

Identifying areas with low patent saturation can highlight opportunities for innovation and new product development.

Licensing and Collaboration

Understanding the patent landscape can facilitate licensing agreements or collaborations with other companies holding relevant patents.

Risk Assessment

Analyzing the patent landscape helps in assessing the risk of patent infringement and the need for defensive strategies such as patent thickets or terminal disclaimers, as seen in cases like the Cellect LLC appeals[1].

Industry Trends and Future Directions

The pharmaceutical industry is highly dynamic, with continuous research and development aimed at discovering new therapeutic agents. Trends in this field include:

Personalized Medicine

There is a growing trend towards personalized medicine, which could involve tailoring sulfamoyl-substituted phenethylamine derivatives to specific patient populations.

Combination Therapies

Combining these derivatives with other therapeutic agents could be a future direction, especially in treating complex diseases.

Regulatory Changes

Changes in regulatory environments, such as new guidelines from the FDA, can impact the development and approval of these compounds.

Key Takeaways

  • Scope and Claims: U.S. Patent 4,731,478 covers the synthesis, preparation, and pharmaceutical compositions of sulfamoyl-substituted phenethylamine derivatives.
  • Patent Landscape: A thorough analysis reveals the competitive landscape, technology saturation, and geographical distribution of related patents.
  • Strategic Insights: This analysis guides business and R&D decisions by identifying innovation areas, licensing opportunities, and risk assessment.
  • Industry Trends: The industry is moving towards personalized medicine, combination therapies, and adapting to regulatory changes.

FAQs

Q: What is the main subject of U.S. Patent 4,731,478?

A: The main subject is sulfamoyl-substituted phenethylamine derivatives, their preparation, and pharmaceutical compositions.

Q: How can one conduct a patent landscape analysis for this patent?

A: Use tools like the USPTO's Patent Public Search, Global Dossier, and international patent databases to identify related patents and competitors.

Q: What are the strategic insights gained from a patent landscape analysis?

A: Insights include identifying innovation areas, licensing opportunities, risk assessment, and understanding industry trends.

Q: How does the patent landscape analysis help in business and R&D decisions?

A: It helps in making long-term decisions about technology pivots, licensing agreements, and defensive strategies against patent infringement.

Q: What are the current trends in the pharmaceutical industry relevant to this patent?

A: Trends include personalized medicine, combination therapies, and adapting to regulatory changes.

Cited Sources

  1. In re Cellect - United States Court of Appeals for the Federal Circuit[1].
  2. PubChem - Sulfamoyl-substituted phenethylamine derivatives, their preparation and pharmaceutical compositions[2].
  3. AcclaimIP - Patent Landscape Analysis[3].
  4. USPTO - Search for patents[4].

More… ↓

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Drugs Protected by US Patent 4,731,478

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 4,731,478

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan55-14382Feb 08, 1980

International Family Members for US Patent 4,731,478

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 0034432 ⤷  Subscribe SPC/GB96/017: EXPIRE United Kingdom ⤷  Subscribe
European Patent Office 0034432 ⤷  Subscribe 96C0048 Belgium ⤷  Subscribe
Argentina 227533 ⤷  Subscribe
Argentina 230433 ⤷  Subscribe
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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