Details for Patent: 6,495,541

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Summary for Patent: 6,495,541

Title:	Tricyclic inhibitors of poly(ADP-ribose) polymerases
Abstract:	Compounds of the formula below are poly(ADP-ribosyl)transferase (PARP) inhibitors, and are useful as therapuetics in treatment of cancers and the amelioration of the effects of stroke, head trauma, and nuerodegenerative disease. ##STR1## As cancer therapuetics, the compounds of the invention may be used, e.g., in combination with cytotoxic agents and/or radiation.
Inventor(s):	Webber; Stephen Evan (San Diego, CA), Canan-Koch; Stacie S. (La Jolla, CA), Tikhe; Jayashree (San Diego, CA), Thoresen; Lars Henrik (College Station, TX)
Assignee:	Agouron Pharmaceuticals, Inc. (La Jolla, CA)
Application Number:	09/479,896
Patent Claim Types: see list of patent claims	Compound; Use; Composition;

Drugs Protected by US Patent 6,495,541

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