Details for Patent: 7,399,488
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Which drugs does patent 7,399,488 protect, and when does it expire?
Patent 7,399,488 protects XTAMPZA ER and is included in one NDA.
This patent has twenty-three patent family members in thirteen countries.
Summary for Patent: 7,399,488
Title: | Abuse-deterrent pharmaceutical compositions of opiods and other drugs |
Abstract: | An abuse-deterrent pharmaceutical composition has been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opiods. In the preferred embodiment, a drug is modified to increase its lipophilicity. In preferred embodiments the modified drug is homogeneously dispersed within microparticles composed of a material that is either slowly soluble or not soluble in water. In some embodiments the drug containing microparticles or drug particles are coated with one or more coating layers, where at least one coating is water insoluble and preferably organic solvent insoluble, but enzymatically degradable by enzymes present in the human gastrointestinal tract. The abuse-deterrent composition retards the release of drug, even if the physical integrity of the formulation is compromised (for example, by chopping with a blade or crushing) and the resulting material is placed in water, snorted, or swallowed. However, when administered as directed, the drug is slowly released from the composition as the composition is broken down or dissolved gradually within the GI tract by a combination of enzymatic degradation, surfactant action of bile acids, and mechanical erosion. |
Inventor(s): | Hirsh; Jane (Wellesley, MA), Kibanov; Alexander M. (Newton, MA), Swager; Timothy M. (Newton, MA), Buchwald; Stephen L. (Newton, MA), Lo; Whe Yong (Canton, MA), Fleming; Alison B. (Marshfield, MA), Rariy; Roman V. (Allston, MA) |
Assignee: | Collegium Pharmaceutical, Inc. (Cumberland, RI) |
Application Number: | 10/614,866 |
Patent Litigation and PTAB cases: | See patent lawsuits and PTAB cases for patent 7,399,488 |
Patent Claim Types: see list of patent claims | Composition; Formulation; Dosage form; |
Patent landscape, scope, and claims: | More… ↓ |
Drugs Protected by US Patent 7,399,488
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Collegium Pharm Inc | XTAMPZA ER | oxycodone | CAPSULE, EXTENDED RELEASE;ORAL | 208090-001 | Apr 26, 2016 | RX | Yes | No | 7,399,488 | ⤷ Subscribe | Y | ⤷ Subscribe | ||||
Collegium Pharm Inc | XTAMPZA ER | oxycodone | CAPSULE, EXTENDED RELEASE;ORAL | 208090-002 | Apr 26, 2016 | RX | Yes | No | 7,399,488 | ⤷ Subscribe | Y | ⤷ Subscribe | ||||
Collegium Pharm Inc | XTAMPZA ER | oxycodone | CAPSULE, EXTENDED RELEASE;ORAL | 208090-003 | Apr 26, 2016 | RX | Yes | No | 7,399,488 | ⤷ Subscribe | Y | ⤷ Subscribe | ||||
Collegium Pharm Inc | XTAMPZA ER | oxycodone | CAPSULE, EXTENDED RELEASE;ORAL | 208090-004 | Apr 26, 2016 | RX | Yes | No | 7,399,488 | ⤷ Subscribe | Y | ⤷ Subscribe | ||||
Collegium Pharm Inc | XTAMPZA ER | oxycodone | CAPSULE, EXTENDED RELEASE;ORAL | 208090-005 | Apr 26, 2016 | RX | Yes | Yes | 7,399,488 | ⤷ Subscribe | Y | ⤷ Subscribe | ||||
>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 7,399,488
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
---|---|---|---|---|---|
Australia | 2003247876 | ⤷ Subscribe | |||
Canada | 2491572 | ⤷ Subscribe | |||
Canada | 2569958 | ⤷ Subscribe | |||
Canada | 2916869 | ⤷ Subscribe | |||
Cyprus | 1119831 | ⤷ Subscribe | |||
Denmark | 1765292 | ⤷ Subscribe | |||
>Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |