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Last Updated: November 17, 2024

Details for Patent: 7,977,488


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Summary for Patent: 7,977,488
Title:1-heterocyclylsulfonyl, 2-aminomethyl, 5-(hetero-) aryl substituted 1-H-pyrrole derivatives as acid secretion inhibitors
Abstract: The present invention provides a compound having a superior acid secretion inhibitory effect and showing an antiulcer activity and the like. The present invention provides a compound represented by the formula (I) wherein R.sup.1 is a nitrogen-containing monocyclic heterocyclic group optionally condensed with a benzene ring or a heterocycle, the nitrogen-containing monocyclic heterocyclic group optionally condensed with a benzene ring or a heterocycle optionally has substituent(s), R.sup.2 is an optionally substituted C.sub.6-14 aryl group, an optionally substituted thienyl group or an optionally substituted pyridyl group, R.sup.3 and R.sup.4 are each a hydrogen atom, or one of R.sup.3 and R.sup.4 is a hydrogen atom and the other is an optionally substituted lower alkyl group, an acyl group, a halogen atom, a cyano group or a nitro group, and R.sup.5 is an alkyl group or a salt thereof. ##STR00001##
Inventor(s): Kajino; Masahiro (Osaka, JP), Hasuoka; Atsushi (Osaka, JP), Nishida; Haruyuki (Osaka, JP)
Assignee: Takeda Pharmaceutical Company Limited (Osaka, JP)
Application Number:11/991,307
Patent Claim Types:
see list of patent claims
Compound;

Drugs Protected by US Patent 7,977,488

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Phathom VOQUEZNA TRIPLE PAK amoxicillin; clarithromycin; vonoprazan fumarate CAPSULE, TABLET, TABLET;ORAL 215152-001 May 3, 2022 RX Yes Yes ⤷  Sign Up ⤷  Sign Up Y ⤷  Sign Up
Phathom VOQUEZNA DUAL PAK amoxicillin; vonoprazan fumarate CAPSULE, TABLET;ORAL 215153-001 May 3, 2022 RX Yes Yes ⤷  Sign Up ⤷  Sign Up Y ⤷  Sign Up
Phathom VOQUEZNA vonoprazan fumarate TABLET;ORAL 215151-001 Nov 1, 2023 RX Yes No ⤷  Sign Up ⤷  Sign Up Y ⤷  Sign Up
Phathom VOQUEZNA vonoprazan fumarate TABLET;ORAL 215151-002 Nov 1, 2023 RX Yes Yes ⤷  Sign Up ⤷  Sign Up Y ⤷  Sign Up
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 7,977,488

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan2005-250356Aug 30, 2005
Japan2006-100626Mar 31, 2006
PCT Information
PCT FiledAugust 29, 2006PCT Application Number:PCT/JP2006/317408
PCT Publication Date:March 08, 2007PCT Publication Number: WO2007/026916

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