Details for Patent: 8,101,743

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Which drugs does patent 8,101,743 protect, and when does it expire?

Patent 8,101,743 protects TEGSEDI and WAINUA (AUTOINJECTOR) and is included in two NDAs.

Summary for Patent: 8,101,743

Title:	Modulation of transthyretin expression
Abstract:	Compounds, compositions and methods are provided for modulating the expression of transthyretin. The compositions comprise oligonucleotides, targeted to nucleic acid encoding transthyretin. Methods of using these compounds for modulation of transthyretin expression and for diagnosis and treatment of diseases and conditions associated with expression of transthyretin are provided.
Inventor(s):	Brown-Driver; Vickie L. (Solana Beach, CA), Jain; Ravi (Fremont, CA)
Assignee:	Isis Pharmaceuticals, Inc. (Carlsbad, CA)
Application Number:	12/273,731
Patent Claim Types: see list of patent claims	Composition; Compound;

Drugs Protected by US Patent 8,101,743

Glossary

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
Akcea Theraps	TEGSEDI	inotersen sodium	SOLUTION;SUBCUTANEOUS	211172-001	Oct 5, 2018		DISCN	Yes	No	⤷ Sign Up	⤷ Sign Up	Y	Y			⤷ Sign Up
Astrazeneca Ab	WAINUA (AUTOINJECTOR)	eplontersen sodium	SOLUTION;SUBCUTANEOUS	217388-001	Dec 21, 2023		RX	Yes	Yes	⤷ Sign Up	⤷ Sign Up	Y	Y			⤷ Sign Up
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

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