Details for Patent: 8,188,113

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Which drugs does patent 8,188,113 protect, and when does it expire?

Patent 8,188,113 protects QINLOCK and is included in one NDA.

This patent has twenty-seven patent family members in ten countries.

Summary for Patent: 8,188,113

Title:	Dihydropyridopyrimidinyl, dihydronaphthyidinyl and related compounds useful as kinase inhibitors for the treatment of proliferative diseases
Abstract:	The present invention relates to novel dihydropyridopyrimidinyl, dihydronaphthyridinyl, and related compounds which are kinase inhibitors and modulator useful for the treatment of various diseases. More particularly, the invention is concerned with such compounds, kinase/compound adducts, methods of treating diseases, and methods of synthesis of the compounds. Preferably, the compounds are useful for the modulation of kinase activity of Raf kinases and disease polymorphs thereof. Compounds of the present invention find utility in the treatment of mammalian cancers and especially human cancers including but not limited to malignant melanoma, colorectal cancer, ovarian cancer, papillary thyroid carcinoma, non small cell lung cancer, and mesothelioma. Compounds of the present invention also find utility in the treatment of rheumatoid arthritis and retinopathies including diabetic retinal neuropathy and macular degeneration.
Inventor(s):	Flynn; Daniel L. (Lawrence, KS), Petillo; Peter A. (Lawrence, KS), Kaufman; Michael D. (Lawrence, KS), Patt; William C. (Lawrence, KS)
Assignee:	Deciphera Pharmaceuticals, Inc. (Lawrence, KS)
Application Number:	11/854,354
Patent Claim Types: see list of patent claims	Composition; Compound;

Drugs Protected by US Patent 8,188,113

Glossary

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
Deciphera Pharms	QINLOCK	ripretinib	TABLET;ORAL	213973-001	May 15, 2020		RX	Yes	Yes	⤷ Sign Up	⤷ Sign Up	Y	Y			⤷ Sign Up
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

International Family Members for US Patent 8,188,113

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Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Australia	2007296441	⤷ Sign Up
Australia	2007296450	⤷ Sign Up
Brazil	122012012032	⤷ Sign Up
Brazil	PI0716844	⤷ Sign Up
Brazil	PI0716981	⤷ Sign Up
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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