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Last Updated: November 17, 2024

Details for Patent: 8,357,697

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Which drugs does patent 8,357,697 protect, and when does it expire?

Patent 8,357,697 protects INGREZZA and INGREZZA SPRINKLE and is included in two NDAs.

This patent has eighteen patent family members in fifteen countries.

Summary for Patent: 8,357,697

Title:	Substituted 3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-A]isoquin- olin-2-ol compounds and methods relating thereto
Abstract:	Substituted 3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquin- olin-2-ol compounds are disclosed that are inhibitors of the vesicular monoamine transporter 2 (VMAT2). The compounds of this invention have the structure: ##STR00001## wherein R.sub.1 is as defined herein, including stereoisomers and pharmaceutically acceptable salts and solvates thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use in a subject in need thereof.
Inventor(s):	Gano; Kyle W. (San Diego, CA)
Assignee:	Neurocrine Biosciences, Inc. (San Diego, CA)
Application Number:	13/237,709
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 8,357,697
Patent Claim Types: see list of patent claims	Use; Composition;

Drugs Protected by US Patent 8,357,697

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
Neurocrine	INGREZZA	valbenazine tosylate	CAPSULE;ORAL	209241-001	Apr 11, 2017	AB	RX	Yes	No	⤷ Sign Up	⤷ Sign Up				A METHOD OF TREATING HUNTINGTON'S CHOREA	⤷ Sign Up
Neurocrine	INGREZZA	valbenazine tosylate	CAPSULE;ORAL	209241-001	Apr 11, 2017	AB	RX	Yes	No	⤷ Sign Up	⤷ Sign Up				TREATMENT OF TARDIVE DYSKINESIA	⤷ Sign Up
Neurocrine	INGREZZA	valbenazine tosylate	CAPSULE;ORAL	209241-003	Apr 23, 2021	AB	RX	Yes	No	⤷ Sign Up	⤷ Sign Up				A METHOD OF TREATING HUNTINGTON'S CHOREA	⤷ Sign Up
Neurocrine	INGREZZA	valbenazine tosylate	CAPSULE;ORAL	209241-003	Apr 23, 2021	AB	RX	Yes	No	⤷ Sign Up	⤷ Sign Up				TREATMENT OF TARDIVE DYSKINESIA	⤷ Sign Up
Neurocrine	INGREZZA	valbenazine tosylate	CAPSULE;ORAL	209241-002	Oct 4, 2017	AB	RX	Yes	Yes	⤷ Sign Up	⤷ Sign Up				TREATMENT OF TARDIVE DYSKINESIA	⤷ Sign Up
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

International Family Members for US Patent 8,357,697

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Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Australia	2007317242	⤷ Sign Up
Brazil	PI0718247	⤷ Sign Up
Canada	2668689	⤷ Sign Up
China	101553487	⤷ Sign Up
Cyprus	1113838	⤷ Sign Up
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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