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Last Updated: July 16, 2024

Details for Patent: 8,361,977


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Which drugs does patent 8,361,977 protect, and when does it expire?

Patent 8,361,977 protects SPINRAZA and is included in one NDA.

This patent has thirty-one patent family members in twelve countries.

Summary for Patent: 8,361,977
Title:Compositions and methods for modulation of SMN2 splicing
Abstract: Disclosed herein are compounds, compositions and methods for modulating splicing of SMN2 mRNA in a cell, tissue or animal. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders, including spinal muscular atrophy.
Inventor(s): Baker; Brenda F. (Carlsbad, CA), Krainer; Adrian R. (Huntington Station, NY), Hua; Yimin (Jericho, NY)
Assignee: Isis Pharmaceuticals, Inc. (Carlsbad, CA)
Application Number:11/993,609
Patent Claim Types:
see list of patent claims
Compound; Composition;

Drugs Protected by US Patent 8,361,977

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Biogen Idec SPINRAZA nusinersen sodium SOLUTION;INTRATHECAL 209531-001 Dec 23, 2016 RX Yes Yes ⤷  Sign Up ⤷  Sign Up Y Y ⤷  Sign Up
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 8,361,977

PCT Information
PCT FiledJune 23, 2006PCT Application Number:PCT/US2006/024469
PCT Publication Date:January 04, 2007PCT Publication Number: WO2007/002390

International Family Members for US Patent 8,361,977

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 1910395 ⤷  Sign Up CA 2017 00054 Denmark ⤷  Sign Up
European Patent Office 1910395 ⤷  Sign Up 300905 Netherlands ⤷  Sign Up
European Patent Office 2548560 ⤷  Sign Up 300902 Netherlands ⤷  Sign Up
European Patent Office 2548560 ⤷  Sign Up PA2017037 Lithuania ⤷  Sign Up
European Patent Office 2548560 ⤷  Sign Up CA 2017 00055 Denmark ⤷  Sign Up
European Patent Office 2548560 ⤷  Sign Up 122017000100 Germany ⤷  Sign Up
European Patent Office 1910395 ⤷  Sign Up 122017000099 Germany ⤷  Sign Up
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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