Details for Patent: 8,486,894
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Which drugs does patent 8,486,894 protect, and when does it expire?
Patent 8,486,894 protects KORSUVA and is included in one NDA.
This patent has forty-nine patent family members in twenty-five countries.
Summary for Patent: 8,486,894
| Title: | Synthetic peptide amides and dimeric forms thereof |
| Abstract: | The invention relates to synthetic peptide amides that are ligands of the kappa opioid receptor and particularly to agonists of the kappa opioid receptor that exhibit low P.sub.450 CYP inhibition and low penetration into the brain. The synthetic peptide amides of the invention conform to the structure: ##STR00001## wherein Xaa is a D-amino acid and G is selected from the following three groups: ##STR00002## The compounds are useful in the prophylaxis and treatment of pain, pruritis and inflammation associated with a variety of diseases and conditions. |
| Inventor(s): | Schteingart; Claudio D. (San Diego, CA), Menzaghi; Frederique (Rye, NY), Jiang; Guangcheng (San Diego, CA), Alexander; Roberta Vezza (San Diego, CA), Sueiras-Diaz; Javier (La Jolla, CA), Spencer; Robert H. (New Hope, PA), Chalmers; Derek T. (Riverside, CT), Luo; Zhiyong (New City, NY) |
| Assignee: | Cara Therapeutics, Inc. (Shelton, CT) |
| Application Number: | 12/773,992 |
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Patent Claim Types: see list of patent claims | Use; Composition; Formulation; Dosage form; |
Drugs Protected by US Patent 8,486,894
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cara Therap | KORSUVA | difelikefalin acetate | SOLUTION;INTRAVENOUS | 214916-001 | Aug 23, 2021 | RX | Yes | Yes | 8,486,894 | ⤷ Subscribe | TREATMENT OF MODERATE-TO-SEVERE PRURITUS ASSOCIATED WITH CHRONIC KIDNEY DISEASE (CKD-AP) IN ADULTS UNDERGOING HEMODIALYSIS (HD) | ⤷ Subscribe | ||||
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 8,486,894
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| European Patent Office | 2064228 | ⤷ Subscribe | 301199 | Netherlands | ⤷ Subscribe |
| European Patent Office | 2064228 | ⤷ Subscribe | CA 2022 00045 | Denmark | ⤷ Subscribe |
| European Patent Office | 2064228 | ⤷ Subscribe | PA2022522 | Lithuania | ⤷ Subscribe |
| European Patent Office | 2064228 | ⤷ Subscribe | LUC00282 | Luxembourg | ⤷ Subscribe |
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
