Details for Patent: 8,530,509

Which drugs does patent 8,530,509 protect, and when does it expire?

Patent 8,530,509 protects TPOXX and is included in one NDA.

This patent has thirty-four patent family members in twelve countries.

Summary for Patent: 8,530,509

Title:	Compounds, compositions and methods for treatment and prevention of orthopoxvirus infections and associated diseases
Abstract:	Methods of using di, tri, and tetracyclic acylhydrazide derivatives and analogs, as well as pharmaceutical compositions containing the same, for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the orthopoxvirus.
Inventor(s):	Jordan; Robert (Corvallis, OR), Bailey; Thomas R. (Phoenixville, PA), Rippin; Susan R. (Wilmington, DE), Dai; Dongcheng (Corvallis, OR)
Assignee:	Siga Technologies, Inc. (Corvallis, OR)
Application Number:	13/194,437
Patent Claim Types: see list of patent claims	Use; Composition; Compound;

Analyzing the Scope and Claims of United States Patent 8,530,509

Introduction to Patent 8,530,509

United States Patent 8,530,509, titled "Compounds, compositions and methods for treatment and prevention of orthopoxvirus infections and associated diseases," is a significant patent in the field of pharmaceuticals and virology. Here, we will delve into the scope, claims, and the broader patent landscape surrounding this invention.

Patent Overview

Publication Number and Authority

• The patent number is US8530509B2, and it was granted by the United States Patent and Trademark Office (USPTO)[4].

Invention Description

• The patent describes the use of di, tri, and tetracyclic acylhydrazide derivatives and their analogs, as well as compositions containing these compounds, for the treatment and prevention of orthopoxvirus infections and associated diseases. Orthopoxviruses include viruses such as smallpox, cowpox, and monkeypox[4].

Scope of the Invention

Compounds and Compositions

• The patent focuses on specific chemical compounds, particularly di, tri, and tetracyclic acylhydrazide derivatives. These compounds are described in detail, including their chemical structures and synthesis methods[4].

Therapeutic Uses

• The primary scope of the invention is the treatment and prevention of orthopoxvirus infections. The patent outlines various methods for using these compounds to inhibit the replication of orthopoxviruses and to treat or prevent diseases caused by these viruses[4].

Claims of the Patent

Independent Claims

• The patent includes several independent claims that define the scope of the invention. These claims cover the specific compounds, their compositions, and the methods for their use in treating or preventing orthopoxvirus infections[4].

Dependent Claims

• Dependent claims further specify the independent claims by detailing particular aspects of the compounds, such as their chemical structures, dosages, and administration methods. These claims help to narrow down the scope and ensure that the invention is clearly defined[4].

Patent Landscape Analysis

Competitors and Related Patents

• To understand the patent landscape, it is crucial to identify other patents and competitors in the same technology area. A patent landscape analysis would reveal other patents related to orthopoxvirus treatments, including those held by competitors like Siga Technologies Inc., which also works on similar compounds and methods[5].

Saturation in the Technology Area

• The technology area of orthopoxvirus treatments is relatively specialized but can be highly saturated. A comprehensive patent landscape analysis would help in identifying areas of high patent saturation and potential gaps where new innovations could be focused[3].

Global Dossier and International Patents

• The Global Dossier service provided by the USPTO allows users to see the patent family for a specific application, including related applications filed at participating IP Offices. This can help in understanding the global patent landscape for orthopoxvirus treatments and identifying potential international competitors[1].

Strategic Insights from Patent Landscape Analysis

Identifying Market Gaps

• A thorough patent landscape analysis can help in identifying market gaps and areas where current technologies are lacking. For example, if there is a high saturation of patents on certain types of compounds, it might be strategic to focus on newer inventive spaces or different approaches to treating orthopoxvirus infections[3].

Competitor Analysis

• By analyzing the patent portfolios of competitors, businesses can gain insights into the strategic directions of their competitors. This can include identifying abandoned technologies, as shown in Figure 3A and 3B of the patent landscape analysis, and understanding where competitors are focusing their resources[3].

Tools and Resources for Patent Search

USPTO Resources

• The USPTO provides several tools and resources for conducting patent searches, including the Patent Public Search tool, Global Dossier, and the Patent and Trademark Resource Centers (PTRCs). These resources can be invaluable in conducting a thorough patent landscape analysis[1].

International Patent Databases

• Searching international patent databases such as those provided by the European Patent Office (EPO), Japan Patent Office (JPO), and the World Intellectual Property Organization (WIPO) can provide a global perspective on the patent landscape for orthopoxvirus treatments[1].

Conclusion

United States Patent 8,530,509 is a significant contribution to the field of virology and pharmaceuticals, particularly in the treatment and prevention of orthopoxvirus infections. Understanding the scope and claims of this patent, as well as the broader patent landscape, is crucial for businesses and researchers looking to innovate in this area.

Key Takeaways

• Specific Compounds: The patent focuses on di, tri, and tetracyclic acylhydrazide derivatives and their analogs.
• Therapeutic Uses: The primary use is the treatment and prevention of orthopoxvirus infections.
• Patent Landscape: The technology area is specialized but can be highly saturated, requiring a comprehensive analysis to identify market gaps and competitor strategies.
• Global Perspective: Utilizing global patent databases and services like Global Dossier can provide a broader understanding of the international patent landscape.
• Strategic Insights: Patent landscape analysis can help in making long-term decisions about technology direction and resource allocation.

FAQs

Q: What is the main focus of United States Patent 8,530,509?

• The main focus is on the use of di, tri, and tetracyclic acylhydrazide derivatives and their analogs for treating and preventing orthopoxvirus infections.

Q: How can one conduct a thorough patent landscape analysis for this technology area?

• By using tools like the USPTO's Patent Public Search, Global Dossier, and international patent databases, and analyzing the patent portfolios of competitors.

Q: What are the benefits of using the Global Dossier service?

• The Global Dossier service allows users to see the patent family for a specific application, including related applications filed at participating IP Offices, and provides access to file histories, classification, and citation data.

Q: How can businesses use patent landscape analysis to make strategic decisions?

• By identifying market gaps, understanding competitor strategies, and recognizing areas of high patent saturation, businesses can make informed decisions about where to focus their resources.

Q: What resources are available for searching international patents related to orthopoxvirus treatments?

• Resources include the European Patent Office (EPO), Japan Patent Office (JPO), World Intellectual Property Organization (WIPO), and other international intellectual property offices.

Sources

1. USPTO - Search for patents: https://www.uspto.gov/patents/search
2. USA.gov - U.S. Patent and Trademark Office (USPTO): https://www.usa.gov/agencies/u-s-patent-and-trademark-office
3. AcclaimIP - Patent Landscape Analysis: https://www.acclaimip.com/patent-landscaping/patent-landscape-analysis-uncovering-strategic-insights/
4. Google Patents - US8530509B2: https://patents.google.com/patent/US8530509B2/en
5. Unified Patents - US-4061763-A: https://portal.unifiedpatents.com/patents/patent/US-4061763-A

Drugs Protected by US Patent 8,530,509

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
Siga Technologies	TPOXX	tecovirimat	SOLUTION;INTRAVENOUS	214518-001	May 18, 2022		RX	Yes	Yes	8,530,509		Y

International Family Members for US Patent 8,530,509

Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
European Patent Office	1638938		301177	Netherlands
European Patent Office	1638938		2022C/521	Belgium
European Patent Office	1638938		122022000032	Germany
European Patent Office	1638938		2290024-5	Sweden