Details for Patent: 9,090,558

Which drugs does patent 9,090,558 protect, and when does it expire?

Patent 9,090,558 protects VUMERITY and is included in one NDA.

This patent has fifty-two patent family members in twenty-six countries.

Summary for Patent: 9,090,558

Title:	Prodrugs of fumarates and their use in treating various diseases
Abstract:	The present invention provides compounds of formula (I), ##STR00001## wherein: R.sub.1 is unsubstituted C.sub.1-C.sub.6 alkyl; L.sub.a is substituted or unsubstituted C.sub.1-C.sub.6 alkyl linker, substituted or unsubstituted C.sub.3-C.sub.10 carbocycle, substituted or unsubstituted heterocycle comprising one or two 5- or 6-member rings and 1-4 heteroatoms selected from N, O and S, or substituted or unsubstituted heteroaryl comprising one or two 5- or 6-member rings and 1-4 heteroatoms selected from N, O and S; and R.sub.2 and R.sub.3 are each, independently, H, substituted or unsubstituted C.sub.1-C.sub.6 alkyl, or substituted or unsubstituted C.sub.6-C.sub.10 aryl; or alternatively, R.sub.2 and R.sub.3, together with the nitrogen atom to which they are attached, form a substituted or unsubstituted heteroaryl comprising one or two 5- or 6-member rings and 1-4 heteroatoms selected from N, O and S or a substituted or unsubstituted heterocycle comprising one or two 5- or 6-member rings and 1-4 heteroatoms selected from N, O and S. The invention also provides pharmaceutical compositions and methods for treating neurological diseases, such as multiple sclerosis.
Inventor(s):	Zeidan; Tarek A. (Watertown, MA), Duncan; Scott (Bedford, MA), Hencken; Christopher P. (Boston, MA), Wynn; Thomas Andrew (Lexington, MA), Sanrame; Carlos N. (Lexington, MA)
Assignee:	Alkermes Pharma Ireland Limited (Dublin, IE)
Application Number:	14/180,687
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 9,090,558
Patent Claim Types: see list of patent claims	Use;

Drugs Protected by US Patent 9,090,558

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
Biogen Inc	VUMERITY	diroximel fumarate	CAPSULE, DELAYED RELEASE;ORAL	211855-001	Oct 29, 2019		RX	Yes	Yes						METHOD OF TREATING MULTIPLE SCLEROSIS

International Family Members for US Patent 9,090,558

Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
European Patent Office	2970101		301165	Netherlands
European Patent Office	2970101		PA2022003	Lithuania
European Patent Office	2970101		2022C/507	Belgium