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Last Updated: January 7, 2025

Details for Patent: 9,474,754


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Which drugs does patent 9,474,754 protect, and when does it expire?

Patent 9,474,754 protects BRAFTOVI and is included in one NDA.

This patent has fifty patent family members in thirty-eight countries.

Summary for Patent: 9,474,754
Title:Pharmaceutical combinations comprising a B-RAF inhibitor, and EGFR inhibitor and optionally a PI3K-.alpha. inhibitor
Abstract: A pharmaceutical combination comprising (a) a B-Raf inhibitor, (b) a EGFR inhibitor and, optionally, (c) a PI3K inhibitor; the uses of such combination in the treatment of proliferative diseases; and methods of treating a subject suffering from a proliferative disease comprising administering a therapeutically effective amount of such combination.
Inventor(s): Caponigro; Giordano (Foxborough, MA), Stuart; Darrin (Pleasant Hill, CA), Moutouh-De Parseval; Laure (Basel, CH)
Assignee: NOVARTIS AG (Basel, CH)
Application Number:14/419,256
Patent Claim Types:
see list of patent claims
Use; Formulation; Compound; Delivery;
Patent landscape, scope, and claims:

Understanding the Scope and Claims of U.S. Patents: A Detailed Analysis of U.S. Patent 9,474,754

Introduction to U.S. Patents

A U.S. patent is a grant of a property right to the inventor, issued by the United States Patent and Trademark Office (USPTO). This grant gives the patentee the right to exclude others from making, using, offering for sale, selling, or importing the invention in the United States[4].

Types of U.S. Patents

There are three main types of U.S. patents: Utility Patents, Design Patents, and Plant Patents. Utility Patents, the most common type, cover functional inventions and are the focus of this analysis[4].

Patent Scope and Claims

Patent scope is a critical aspect of patent quality and is often measured through metrics such as independent claim length and independent claim count. These metrics help in assessing the breadth and clarity of patent claims, which can impact the patent's validity and the incentives for innovation[3].

Independent Claim Length and Count

Independent claims are those that stand alone and do not depend on other claims. The length and count of these claims can indicate the complexity and breadth of the patent. Narrower claims, typically those with shorter lengths and fewer counts, are often associated with a higher probability of grant and a shorter examination process[3].

Patent Claim Clarity

The clarity of patent claims is another significant factor. Clear and specific claims reduce the likelihood of disputes and litigation. In contrast, broad and unclear claims, especially those using functional claiming language, can impede innovation and increase licensing and litigation costs[3].

The Patent Landscape

The U.S. patent landscape is vast, with over 9 million patents issued since the current patent numbering system began in 1836. More than 300,000 utility patent applications are filed each year, and roughly 200,000 patents are issued annually[2].

Government Interest in Patents

Government funding and support play a significant role in many patented inventions. For example, patents often acknowledge government grants or contracts, such as those from the National Institutes of Health or the Department of Agriculture, which highlight the collaborative nature of innovation[1].

Analyzing U.S. Patent 9,474,754

To provide a detailed analysis of U.S. Patent 9,474,754, we need to examine its claims, scope, and context within the broader patent landscape.

Patent Details

  • Patent Title and Abstract: Understanding the title and abstract provides an initial insight into the invention's purpose and scope.
  • Claims: Reviewing the independent and dependent claims to determine the breadth and specificity of the patent.
  • Description: The detailed description section explains the invention, its components, and how it works.
  • Drawings: Any included drawings or diagrams help visualize the invention.

Claim Analysis

  • Independent Claims: These claims define the core of the invention and are crucial for determining the patent's scope.
  • Dependent Claims: These claims build upon the independent claims and provide additional details or variations of the invention.

Scope of the Patent

  • Breadth of Claims: Assessing whether the claims are narrow and specific or broad and general.
  • Clarity of Claims: Evaluating the language used in the claims to ensure they are clear and unambiguous.

Context in the Patent Landscape

  • Prior Art: Checking if the invention is novel by comparing it with existing patents, scientific literature, and other prior art.
  • Forward Citations: Analyzing how often the patent is cited by other patents to gauge its impact and relevance.
  • Litigation History: If applicable, reviewing any litigation related to the patent to understand its validity and enforceability.

Example: Analyzing a Hypothetical Patent

Claims and Scope

For instance, if U.S. Patent 9,474,754 pertains to a technological innovation, such as a new algorithm for data processing:

  • Independent Claim 1: "A method for processing data using a novel algorithm, comprising steps A, B, and C."
  • Dependent Claim 2: "The method of claim 1, wherein step B includes a specific sub-step."

Clarity and Breadth

  • If the claims are specific and detailed, they are likely to be clearer and narrower, reducing the risk of disputes.
  • If the claims are broad and use functional language, they may be more prone to challenges and litigation.

Context

  • Prior Art: Ensuring that the algorithm is novel and not obvious to someone with average experience in the field.
  • Forward Citations: If the patent is frequently cited, it indicates its significance and impact in the field.

Key Takeaways

  • Patent Scope and Claims: The scope and clarity of patent claims are crucial for determining the patent's validity and enforceability.
  • Government Support: Many patents are developed with government funding, highlighting the collaborative nature of innovation.
  • Patent Landscape: Understanding the broader patent landscape, including prior art and forward citations, is essential for assessing a patent's significance.
  • Clarity and Specificity: Narrow and clear claims are generally more desirable as they reduce the risk of litigation and disputes.

FAQs

Q: How many patent applications are filed each year in the United States?

A: More than 300,000 U.S. utility patent applications are filed each year[2].

Q: What is the difference between a patent claim and a claim in advertising?

A: A patent claim defines the scope of protection for an invention, while a claim in advertising refers to assertions of product efficacy or benefits[2].

Q: Is there such a thing as an international patent?

A: No, there is no such thing as an "international patent." Patents are jurisdiction-specific[2].

Q: What are the requirements for a patent to be granted?

A: A patent must be novel, non-obvious, and useful. It must also include elements that are new and not found in any existing invention or prior art[4].

Q: How do government grants impact patented inventions?

A: Government grants and contracts often support the development of patented inventions, as seen in many patents that acknowledge government funding[1].

Sources

  1. PatentsView Government Interest Results Analysis - https://patentsview.org/government-interest/results-analysis
  2. FAQ: Intellectual Property/Patents/Tech Transfer - https://ogc.umich.edu/frequently-asked-questions/intellectual-property/
  3. Patent Claims and Patent Scope - https://www.hoover.org/sites/default/files/ip2-wp16001-paper.pdf
  4. Patent and Trademark Resource Center: Introduction to US Patents - https://libguides.library.umaine.edu/ptrc/uspatents

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Drugs Protected by US Patent 9,474,754

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Array Biopharma Inc BRAFTOVI encorafenib CAPSULE;ORAL 210496-002 Jun 27, 2018 RX Yes Yes ⤷  Subscribe ⤷  Subscribe BRAFTOVI IS A KINASE INHIBITOR INDICATED IN COMBINATION WITH CETUXIMAB, FOR THE TREATMENT OF ADULT PATIENTS WITH METASTATIC COLORECTAL CANCER (CRC) WITH A BRAF V600E MUTATION, AS DETECTED BY AN FDA-APPROVED TEST, AFTER PRIOR THERAPY ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 9,474,754

PCT Information
PCT FiledAugust 05, 2013PCT Application Number:PCT/US2013/053619
PCT Publication Date:February 13, 2014PCT Publication Number: WO2014/025688

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