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Last Updated: December 22, 2024

ABITREXATE Drug Patent Profile


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When do Abitrexate patents expire, and what generic alternatives are available?

Abitrexate is a drug marketed by Abic and is included in four NDAs.

The generic ingredient in ABITREXATE is methotrexate sodium. There are twenty drug master file entries for this compound. Twenty-eight suppliers are listed for this compound. Additional details are available on the methotrexate sodium profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Abitrexate

A generic version of ABITREXATE was approved as methotrexate sodium by HIKMA on September 16th, 1986.

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Summary for ABITREXATE
US Patents:0
Applicants:1
NDAs:4
Raw Ingredient (Bulk) Api Vendors: 137
Clinical Trials: 96
DailyMed Link:ABITREXATE at DailyMed
Drug patent expirations by year for ABITREXATE
Recent Clinical Trials for ABITREXATE

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
City of Hope Medical CenterPhase 2
Children's Oncology GroupPhase 2/Phase 3
Children's Oncology GroupPhase 1/Phase 2

See all ABITREXATE clinical trials

US Patents and Regulatory Information for ABITREXATE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Abic ABITREXATE methotrexate sodium INJECTABLE;INJECTION 089161-001 Mar 10, 1987 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Abic ABITREXATE methotrexate sodium INJECTABLE;INJECTION 089356-001 Jul 17, 1987 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Abic ABITREXATE methotrexate sodium INJECTABLE;INJECTION 089354-001 Jul 17, 1987 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Abic ABITREXATE methotrexate sodium INJECTABLE;INJECTION 089355-001 Jul 17, 1987 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

ABITREXATE Market Analysis and Financial Projection Experimental

Methotrexate Drug Market Dynamics and Financial Trajectory

Introduction to Methotrexate

Methotrexate is a versatile medication widely used in the treatment of various severe health conditions, including cancer, autoimmune diseases, and ectopic pregnancies. Its broad application and FDA approval have made it a significant player in the pharmaceutical market.

Current Market Size and Growth

As of 2022, the global methotrexate drug market was valued at USD 532.4 million, with a Compound Annual Growth Rate (CAGR) of 2.7%. This market is expected to grow and reach a valuation of USD 622.8 million by 2028[1].

However, looking ahead to a longer forecast period, the market is projected to expand more significantly. By 2034, the methotrexate drug market is anticipated to reach a valuation of USD 1,058 million, growing at a CAGR of 5.5% from 2024 to 2034[3].

Key Drivers of Market Growth

Increasing Prevalence of Chronic Diseases

The rising prevalence of chronic diseases such as autoimmune disorders and cancer globally is a major driver of the methotrexate market. Health professionals are increasingly prescribing methotrexate as an effective treatment for these conditions, contributing to its growing demand[3].

Growing Geriatric Population

The aging population is another significant factor driving the demand for methotrexate. Older individuals are more prone to chronic diseases, and the growing geriatric population is expected to continue fueling the market growth[3].

Rise of Biosimilars

The increasing need for affordable alternative drugs, such as biosimilars, is also driving the methotrexate market. Biosimilars offer patients access to treatments that are similar to branded drugs but at a lower cost, making methotrexate more accessible to a wider population[3].

Advances in Drug Delivery Systems

Improvements in drug delivery systems, particularly injectable formulations, are enhancing patient compliance and convenience. These advancements are expected to contribute to the market's growth by making methotrexate administration easier and safer[3].

Increasing Healthcare Spending and Infrastructure

In emerging nations, the surge in healthcare spending and infrastructure improvements are creating favorable conditions for the methotrexate market. This includes the development of more patient-compliant and safe injectable technologies[3].

Market Challenges

Impact of COVID-19

The COVID-19 pandemic had a significant impact on the methotrexate market. Strict lockdowns and supply chain disruptions led to a scarcity of Active Pharmaceutical Ingredients (APIs) needed to manufacture methotrexate, resulting in reduced market growth during the pandemic period[1].

High Cost and Side Effects

While not specific to methotrexate, the high cost of treatments and side effects associated with cancer therapies can act as restraints for the broader market. However, methotrexate's established efficacy and relatively lower cost compared to some newer therapies mitigate these concerns to some extent[4].

Regional Market Dynamics

United States

The U.S. market is expected to register a CAGR of 5.7% from 2024 to 2034. The rising concerns about cancer and autoimmune diseases, along with expanding healthcare expenditure and a shift toward value-based care, are key factors driving growth in this region[3].

China

China's methotrexate market is projected to grow at a CAGR of 5.9% during the forecast period. The increasing healthcare infrastructure and spending in China are expected to support this growth[3].

Other Regions

Other regions, such as the United Kingdom, Japan, and South Korea, are also expected to see significant growth, with CAGRs ranging from 5.7% to 7.0% during the forecast period[3].

Competitive Landscape

The methotrexate market is characterized by the presence of several key players. Some of the prominent companies include:

  • Pfizer Inc.: Known for its strong generics and branded business portfolios[1].
  • Amneal Pharmaceuticals, Inc.: An integrated specialty pharmaceutical company with a diverse portfolio of generic and branded drugs[1].
  • Other significant players in the broader pharmaceutical market, such as Bristol-Myers Squibb Company, AstraZeneca plc, and Roche Holdings AG, also play a role in the methotrexate market[4].

Recent Developments and Trends

Precision Medicine

The advancement of precision medicine is expected to optimize dosage methods and improve treatment outcomes for methotrexate. Personalized medical care based on individual patient characteristics is gaining traction, which could further drive the demand for methotrexate[3].

Integrative Medicine

The increasing interest in integrative medicine, which combines traditional Western medicine with complementary therapies, is also expected to create lucrative opportunities for the methotrexate market in regions like the United States[3].

Financial Trajectory

The financial trajectory of the methotrexate market is positive, driven by the factors mentioned above. Here are some key financial projections:

  • 2022: The market was valued at USD 532.4 million[1].
  • 2024: The market is projected to be valued at USD 621.3 million[3].
  • 2028: The market is expected to reach USD 622.8 million[1].
  • 2034: The market is anticipated to reach USD 1,058 million, growing at a CAGR of 5.5% from 2024 to 2034[3].

Key Takeaways

  • The methotrexate market is driven by the increasing prevalence of chronic diseases, a growing geriatric population, and advances in drug delivery systems.
  • The market faced challenges during the COVID-19 pandemic but is expected to recover and grow significantly.
  • Regional markets, particularly in the U.S., China, and other emerging nations, are expected to drive growth.
  • Key players are investing in research and development to optimize treatment outcomes.
  • Precision medicine and integrative medicine trends are likely to further boost the market.

FAQs

Q: What is the current market size of the methotrexate drug market? A: As of 2022, the global methotrexate drug market was valued at USD 532.4 million[1].

Q: What is the projected CAGR for the methotrexate market from 2024 to 2034? A: The methotrexate market is expected to grow at a CAGR of 5.5% from 2024 to 2034[3].

Q: Which regions are expected to drive the growth of the methotrexate market? A: The United States, China, and other emerging nations are expected to drive the growth of the methotrexate market[3].

Q: How has the COVID-19 pandemic affected the methotrexate market? A: The COVID-19 pandemic led to supply chain disruptions and a scarcity of APIs, negatively impacting the market growth during the pandemic period[1].

Q: What are some of the key drivers of the methotrexate market? A: Key drivers include the increasing prevalence of chronic diseases, a growing geriatric population, the rise of biosimilars, and advances in drug delivery systems[3].

Sources

  1. Business Research Insights: "5 Prominent Players in the Methotrexate Drug Market, 2023"
  2. ACS Publications: "Multiparametric High-Content Cell Painting Identifies Copper ..."
  3. Future Market Insights: "Methotrexate Drug Market Size, Share, Trends & Forecast by 2034"
  4. InsightAce Analytic: "Head and Neck Cancer Market Share, Size, Growth and Forecast to 2031"

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