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Last Updated: December 26, 2024

ADVIL MIGRAINE LIQUI-GELS Drug Patent Profile


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When do Advil Migraine Liqui-gels patents expire, and what generic alternatives are available?

Advil Migraine Liqui-gels is a drug marketed by Haleon Us Holdings and is included in one NDA.

The generic ingredient in ADVIL MIGRAINE LIQUI-GELS is ibuprofen. There are sixty-four drug master file entries for this compound. Two hundred and forty suppliers are listed for this compound. Additional details are available on the ibuprofen profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Advil Migraine Liqui-gels

A generic version of ADVIL MIGRAINE LIQUI-GELS was approved as ibuprofen by STRIDES PHARMA on September 24th, 1986.

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Drug patent expirations by year for ADVIL MIGRAINE LIQUI-GELS
Recent Clinical Trials for ADVIL MIGRAINE LIQUI-GELS

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
Brigham and Women's HospitalPhase 4
National Headache FoundationPhase 1
VA Connecticut Healthcare SystemPhase 1

See all ADVIL MIGRAINE LIQUI-GELS clinical trials

Pharmacology for ADVIL MIGRAINE LIQUI-GELS

US Patents and Regulatory Information for ADVIL MIGRAINE LIQUI-GELS

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Haleon Us Holdings ADVIL MIGRAINE LIQUI-GELS ibuprofen CAPSULE;ORAL 020402-002 Mar 16, 2000 OTC Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

EU/EMA Drug Approvals for ADVIL MIGRAINE LIQUI-GELS

Company Drugname Inn Product Number / Indication Status Generic Biosimilar Orphan Marketing Authorisation Marketing Refusal
Recordati Rare Diseases Pedea ibuprofen EMEA/H/C/000549
Treatment of a haemodynamically significant patent ductus arteriosus in preterm newborn infants less than 34 weeks of gestational age.
Authorised no no no 2004-07-28
>Company >Drugname >Inn >Product Number / Indication >Status >Generic >Biosimilar >Orphan >Marketing Authorisation >Marketing Refusal

ADVIL MIGRAINE LIQUI-GELS Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Advil Migraine Liqui-Gels

Introduction to Advil Migraine Liqui-Gels

Advil Migraine Liqui-Gels are a formulation of ibuprofen designed specifically to target and relieve migraine pain and associated symptoms such as nausea, photophobia, and phonophobia. These liquid-filled capsules are clinically proven and FDA-approved for over-the-counter (OTC) use, making them a popular choice for migraine sufferers.

Efficacy and Safety Profile

Advil Migraine Liqui-Gels have demonstrated significant efficacy in clinical trials. A study involving 729 migraine sufferers showed that ibuprofen liquigels were superior to placebo in relieving pain, ancillary symptoms, and limitation of activity. The headache response rates at 2 hours were 64%, 72%, and 72% for 200mg, 400mg, and 600mg doses, respectively, compared to 50% for the placebo group[1].

The safety profile of Advil Migraine Liqui-Gels is favorable, especially when used as directed. Ibuprofen at OTC doses has a low incidence of serious gastrointestinal (GI) events and minimal risk of causing renal and cardiovascular events. Clinical studies have confirmed that ibuprofen has a low risk of acute liver damage and is generally well tolerated at lower OTC doses[2].

Market Size and Growth

The market for Advil Migraine Liqui-Gels is part of the broader ibuprofen and pain relief markets, which are experiencing significant growth.

  • The global Advil market was valued at $21.01 billion in 2023 and is projected to reach $31.03 billion by 2031, growing at a CAGR of 5.1% during the forecast period[4].
  • The ibuprofen API market, which includes the active ingredient in Advil Migraine Liqui-Gels, was valued at over $715 million in 2024 and is expected to cross $936 million by 2037, growing at a CAGR of more than 2.1%[3].

Driving Factors

Several factors are driving the growth of the Advil Migraine Liqui-Gels market:

Rising Prevalence of Chronic Illnesses

The increasing prevalence of chronic illnesses such as fibromyalgia, arthritis, and migraines is a significant driver. As the global population ages, the demand for effective and easily accessible pain management treatments like Advil Migraine Liqui-Gels increases[4].

Expanding Distribution Channels

The growth of distribution networks, including pharmacies, supermarkets, and online retailers, has made OTC painkillers like Advil Migraine Liqui-Gels more accessible to consumers. The rise in e-commerce, particularly post-COVID-19, has further boosted sales by allowing customers to purchase products conveniently from home[4].

Marketing and Promotional Strategies

Effective marketing and promotional strategies have played a crucial role in increasing customer awareness and adoption of Advil Migraine Liqui-Gels. Strategic alliances and partnerships between manufacturers and retailers have enhanced product visibility and helped maintain a competitive edge in the pain relief market[4].

Regional Market Dynamics

North America

The North American market is expected to see notable growth due to the rising prevalence of migraines, which is partly attributed to the sedentary lifestyle of the population. In the US, ibuprofen has been an OTC drug for over 25 years, making it a well-established and trusted option for managing migraine headaches[3].

Europe

Europe has a strong healthcare system and a large customer base that is aware of pain management options. Countries like Germany, France, and the UK have a high propensity for self-medication, driving demand for Advil Migraine Liqui-Gels[4].

Asia-Pacific

The Asia-Pacific region shows varied growth trends due to differing healthcare access and lifestyle changes. Western drugs, including Advil Migraine Liqui-Gels, are becoming more accepted, and healthcare spending is increasing in countries like China and India[4].

Middle East and Africa

The market in the Middle East and Africa is growing gradually due to urbanization and changing consumer habits, despite challenges with healthcare infrastructure[4].

Latin America

Latin America is also experiencing growth driven by consumers' demand for reliable pain relief options, increasing disposable income, and growing health consciousness[4].

Regulatory Environment

The regulatory environment plays a critical role in the market dynamics of Advil Migraine Liqui-Gels. Strict regulations by agencies like the FDA require significant investment in research and development to ensure safety and efficacy. These regulations can slow the time to market for new formulations and increase compliance costs, which can impact profit margins[4].

Competitive Landscape

The market for Advil Migraine Liqui-Gels faces competition from other pain relief medications, including Tylenol products that contain acetaminophen. However, Advil Migraine Liqui-Gels have a unique advantage as the only FDA-approved OTC migraine medicine in a liquid-filled capsule, which targets pain at the source[5].

Price Sensitivity

Consumers' price sensitivity is a significant challenge. The rising costs of living and healthcare have made consumers more frugal, often opting for cheaper alternatives. This necessitates marketing strategies that highlight the effectiveness and added value of Advil Migraine Liqui-Gels compared to generic or cheaper options[4].

Financial Trajectory

Given the growth drivers and market dynamics, the financial trajectory for Advil Migraine Liqui-Gels is positive.

  • The increasing demand for pain management treatments, coupled with expanding distribution channels and effective marketing strategies, is expected to drive revenue growth.
  • The projected CAGR of 5.1% for the Advil market and over 2.1% for the ibuprofen API market indicates a stable and growing financial outlook[3][4].

Key Takeaways

  • Efficacy and Safety: Advil Migraine Liqui-Gels are clinically proven to relieve migraine pain and associated symptoms with a favorable safety profile.
  • Market Growth: The market is driven by the rising prevalence of chronic illnesses, expanding distribution channels, and effective marketing strategies.
  • Regional Dynamics: North America, Europe, Asia-Pacific, Middle East and Africa, and Latin America each present unique growth opportunities.
  • Regulatory Environment: Strict regulations impact the time to market and compliance costs but ensure safety and efficacy.
  • Competitive Landscape: Advil Migraine Liqui-Gels face competition but maintain a unique market position as the only FDA-approved OTC migraine medicine in a liquid-filled capsule.

FAQs

Q: What is the active ingredient in Advil Migraine Liqui-Gels?

A: The active ingredient in Advil Migraine Liqui-Gels is ibuprofen[5].

Q: Are Advil Migraine Liqui-Gels FDA-approved?

A: Yes, Advil Migraine Liqui-Gels are FDA-approved for OTC use[5].

Q: How do Advil Migraine Liqui-Gels compare to Tylenol products?

A: Advil Migraine Liqui-Gels contain ibuprofen, which targets pain at the source, whereas Tylenol products contain acetaminophen, which blocks pain signals. Tylenol is not indicated for migraine headaches[5].

Q: What are the common side effects of Advil Migraine Liqui-Gels?

A: When used as directed, Advil Migraine Liqui-Gels have a low incidence of serious side effects. However, higher doses of ibuprofen can be associated with gastrointestinal side effects[2].

Q: How is the market for Advil Migraine Liqui-Gels expected to grow in the future?

A: The market for Advil Migraine Liqui-Gels is expected to grow at a CAGR of over 5% driven by increasing demand for pain management treatments, expanding distribution channels, and effective marketing strategies[4].

Sources

  1. Kellstein, D. E., et al. "Ibuprofen in the treatment of migraine: a review of the evidence." Headache: The Journal of Head and Face Pain, vol. 40, no. 7, 2000, pp. 539-546[1].
  2. Haleon Health Partner. "Advil Liqui-Gels - Haleon Health Partner." Haleon Health Partner, 2023[2].
  3. Research Nester. "Ibuprofen API Market Size & Share, Growth Trends 2037." Research Nester, 2024[3].
  4. Verified Market Research. "Advil Market Size, Share, Trends, Opportunities And Forecast." Verified Market Research, 2023[4].
  5. Advil. "Advil Migraine Relief (Ibuprofen): Dosage & Ingredients." Advil, 2023[5].

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